DAF-FM DA (NO荧光探针)(S0019)

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DAF-FM DA (NO荧光探针)

产品编号: S0019

产品包装:>100次
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>100次

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718.00 10

价格: ¥ 718.00

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产品编号 产品名称 产品包装 产品价格
S0019 DAF-FM DA (NO荧光探针) >100次 718.00元

DAF-FM DA即3-Amino,4-aminomethyl-2′,7′-difluorescein, diacetate，也称DAF-FM diacetate或4-Amino,5-
aminomethyl-2′,7′-difluorescein, diacetate。DAF-FM DA是最新一代用于一氧化氮定量检测的荧光探针，比以前比较常用的一氧化氮荧光检测探针DAF-2 diacetate有多方面的改进。首先，DAF-FM DA和DAF-2 diacetate相比，最后和一氧化氮反应形成的荧光产物受pH值的影响小，在pH值大于5.5时不受pH值的影响。其次，DAF-FM DA和DAF-2 diacetate相比，前者产生的荧光更加稳定，不容易淬灭，这样更加便于检测。另外，DAF-FM DA和DAF-2 diacetate相比，前者对一氧化氮的检测灵敏度更高，相同条件下检测灵敏度可以提高接近2倍，最低检测浓度可以达到3nM。

DAF-FM DA (NO荧光探针)(S0019)

   DAF-FM DA可以穿过细胞膜(cell-permeable)，进入细胞后可以被细胞内的酯酶催化形成不能穿过细胞膜的DAF-FM。DAF-FM本身仅有很弱的荧光，但在和一氧化氮反应后可以产生强烈荧光，激发波长为495nm，发射波长为515nm。DAF-FM DA检测一氧化氮的机制可以参考上图。任何可以检测fluorescein的仪器，包括荧光显微镜、激光共聚焦显微镜、流式细胞仪、荧光分光光度计或荧光酶标仪都可以用于该荧光探针的检测。右图为DAF-FM在不同浓度一氧化氮存在时的发射荧光扫描图谱(fluorescence emission spectra)。
DAF-FM DA的分子量为496.4，分子式为C25H18F2N2O7，HPLC分析纯度大于98%。
本DAF-FM DA为溶解于DMSO的淡黄色溶液，浓度为5mM。

DAF-FM DA (NO荧光探针)(S0019)

  本荧光探针适合于检测细胞内的一氧化氮水平，可以进行实时检测。如果收集细胞后再装载探针，通常至少可以检测100个样品。

包装清单：

产品编号 产品名称 包装
S0019-1 DAF-FM DA(NO荧光探针)5mM 20μl
S0019-2 DAF-FM DA稀释液 50ml
— 说明书 1份

保存条件：
-20℃保存，DAF-FM DA需避光保存，一年有效。
注意事项：
BSA和酚红(phenol red)对本荧光探针的检测有干扰，需避免。
第一次使用时请分装成小包装后-20℃保存，以避免反复冻融。
荧光探针应随用随配。配制好的探针工作液应立即使用，不能以后再用。
DAF-FM DA在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内，可以20-25℃水浴温育片刻至全部融解后使用。
      本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。

使用说明：
1. 装载探针
对于刺激时间较短(通常为2小时以内)的细胞，先装载探针，后用适当的阳性对照及自己感兴趣的药物刺激细胞。对于细胞刺激时间较长(通常为6小时以上)的细胞，先用适当的阳性对照及自己感兴趣的药物刺激细胞，后装载探针。
原位装载探针：本方法仅适用于贴壁培养细胞。按照1:1000比例，用本试剂盒提供的DAF-FM DA稀释液稀释DAF-FM DA，使终浓度为5微摩尔/升。去除细胞培养液，加入适当体积稀释好的DAF-FM DA。加入的体积以能充分盖住细胞为宜，通常对于六孔板的一个孔加入稀释好的DAF-FM DA的体积为1毫升。37℃细胞培养箱内孵育20分钟。用PBS(pH7.4)洗涤细胞三次，以充分去除未进入细胞内的DAF-FM DA。
收集细胞后装载探针：按照1:1000比例，用本试剂盒提供的DAF-FM DA稀释液稀释DAF-FM DA，使终浓度为5微摩尔/升。细胞收集后，用稀释好的DAF-FM DA重悬细胞，细胞浓度为一百万至二千万/毫升，37℃细胞培养箱内孵育20分钟。上述操作可以在离心管内进行。每隔3-5分钟颠倒混匀一下，使探针和细胞充分接触。用PBS(pH7.4)洗涤细胞三次，以充分去除未进入细胞内的DAF-FM DA。直接用适当的阳性对照或自己感兴趣的药物刺激细胞，或把细胞等分成若干份后再刺激细胞。
2. 检测
对于原位装载探针的样品可以用激光共聚焦显微镜直接观察(用普通的荧光显微镜观察效果相对较差)，或收集细胞后用荧光分光光度计、荧光酶标仪或流式细胞仪检测。对于收集细胞后装载探针的样品可以用荧光分光光度计、荧光酶标仪或流式细胞仪检测，用激光共聚焦显微镜直接观察也可以。
3. 参数设置
使用495nm激发波长，515nm发射波长，实时、逐时间点或单时间点检测刺激前后荧光的强弱。DAF-FM和 一氧化氮反应产物的荧光光谱和fluorescein非常相似，可以用检测fluorescein的参数设置进行检测，用检测FITC的参数设置进行检测也可以。
4. 其它说明
上述推荐的DAF-FM DA的工作浓度为5微摩尔/升，对于某些细胞，如果发现没有刺激的阴性对照细胞荧光也比较强，可以按照1:2000-1:5000的比例稀释DAF-FM DA，使装载探针时DAF-FM DA的浓度为1-2.5微摩尔/升。相反，如果发现用感兴趣的药物刺激后荧光较弱，可以把DAF-FM DA的工作浓度为调整为10微摩尔/升，以提高检测的灵敏度。另外，探针装载的时间也可以根据情况在15-60分钟内适当进行调整。

DAF-FM DA (NO荧光探针)(S0019)

相关产品请点击如下按钮：
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62. Li J, Wang Y, Wang Y, Wen X, Ma XN, Chen W, Huang F, Kou J, Qi LW, Liu B, Liu K.
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction.
J Mol Cell Cardiol . 2015 Sep;86:62-74. (IF 4.133)

63. Liu L, Wang D, Wang J, Ji H, Zhang Y.
NOAD, a novel nitric oxide donor, induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma Bel-7402 cells.
Toxicol In Vitro . 2015 Oct;29(7):1289-97. (IF 2.959)

64. Wang M, Chen M, Ding Y, Zhu Z, Zhang Y, Wei P, Wang J, Qiao Y, Li L, Li Y, Wen A.
Pretreatment with β-Boswellic Acid Improves Blood Stasis Induced Endothelial Dysfunction: Role of eNOS Activation.
SCI REP-UK . 2015 Oct 20;5:15357. (IF 3.998)

65. Liu J, Jin X, Zhao N, Ye X, Ying C.
Bisphenol A promotes X-linked inhibitor of apoptosis protein-dependent angiogenesis via G protein-coupled estrogen receptor pathway.
J Appl Toxicol . 2015 Nov;35(11):1309-17. (IF 2.997)

66. Zhang G, Wong YH, Zhang Y, He LS, Xu Y, Qian PY.
Nitric oxide inhibits larval settlement in Amphibalanus amphitrite cyprids by repressing muscle locomotion and molting.
Proteomics . 2015 Nov;15(22):3854–64. (IF 3.254)

67. Zhang Y, Shi H, Liang S, Ning G, Xu N, Lu J, Liu X, Lin F.
MoARG1, MoARG5,6 and MoARG7 involved in arginine biosynthesis are essential for growth, conidiogenesis, sexual reproduction, and pathogenicity in Magnaporthe oryzae.
Microbiol Res . 2015 Nov;180:11-22. (IF 3.97)

68. Zhang GH, Chao M, Hui LH, Xu DL, Cai WL, Zheng J, Gao M, Zhang MX, Wang J, Lu QH.
Poly(ADP-ribose)Polymerase 1 Inhibition Protects Against Age-Dependent Endothelial Dysfunction.
CLIN EXP PHARMACOL P  . 2015 Dec;42(12):1266–74 . (IF 2.092)

69. Zhao W, Wu C, Chen X.
Cryptotanshinone Inhibits oxidized LDL-Induced Adhesion Molecule Expression via ROS Dependent NF-κB Pathways.
CELL ADHES MIGR . 2016;10(3):248-58. (IF 3.694)

70. Ma Y, Zhao P, Zhu J, Yan C, Li L, Zhang H, Zhang M, Gao X, Fan X.
Naoxintong Protects Primary Neurons from Oxygen-Glucose Deprivation/Reoxygenation
EVID-BASED COMPL ALT . 2016;2016:5815946. (IF 1.813)

71. Lu C, Zhou F, Wu S, Liu L, Xing D,2.
Phototherapy-Induced Antitumor Immunity: Long-Term Tumor Suppression Effects via Photoinactivation of Respiratory Chain Oxidase-Triggered Superoxide Anion Burst.
ANTIOXID REDOX SIGN . 2016 Feb;24(5):249-62. (IF 6.323)

72. Ren B, Qin W, Wu F, Wang S, Pan C, Wang L, Zeng B, Ma S, Liang J.
Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type2 diabetic rats.
Eur J Pharmacol . 2016 Feb 15;773:13-23. (IF 3.263)

73. Li Y, Xu J, Jiang F, Jiang Z, Liu C, Li L, Luo Y, Lu R, Mu Y, Liu Y, Xue B.
G protein-coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice.
NEUROGASTROENT MOTIL . 2016 Mar;28(3):432–42 . (IF 2.946)

74. Zou P, Xia Y, Chen W, Chen X, Ying S, Feng Z, Chen T, Ye Q, Wang Z, Qiu C, Yang S, Liang G.
EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.
ONCOTARGET . 2016 Apr 5;7(14):18050-64. (IF 5.168)

75. Liu Z, Jiang C, Zhang J, Liu B, Du Q.
Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities.
J Diabetes . 2016 May;8(3):324–35 . (IF 3.28)

76. Quan YY, Qin GQ, Huang H, Liu YH, Wang XP, Chen TS.
Dominant roles of Fenton reaction in sodium nitroprusside-induced chondrocyte apoptosis.
FREE RADICAL BIO MED . 2016 May;94:135-44. (IF 6.17)

77. Zhang Y, Chen S, Hao X, Su JQ, Xue X, Yan Y, Zhu YG, Ye J.
Transcriptomic Analysis Reveals Adaptive Responses of an Enterobacteriaceae Strain LSJC7 to ArsenicExposure.
Front Microbiol . 2016 May 2;7:636. (IF 4.235)

78. Zou P, Xia Y, Ji J, Chen W, Zhang J, Chen X, Rajamanickam V, Chen G, Wang Z, Chen L, Wang Y, Yang S, Liang G.
Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.
Cancer Lett . 2016 May 28;375(1):114-26. (IF 7.36)

79. Batumalaie K, Amin MA, Murugan DD, Sattar MZ, Abdullah NA.
Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction throughsuppression of oxidative stress and inflammation.
SCI REP-UK . 2016 Jun 2;6:27236. (IF 3.998)

80. Li DD, Yang CC, Liu P, Wang Y, Sun Y.
Effect of Nitric Oxide on the Antifungal Activity of Oxidative Stress and Azoles Against Candida albicans.
Indian J Microbiol . 2016 Jun;56(2):214-8. (IF 1.83)

81. Liao Z, Yan Y, Dong H, Zhu Z, Jiang Y, Cao Y.
Endogenous nitric oxide accumulation is involved in the antifungal activity of Shikonin against Candidaalbicans.
EMERG MICROBES INFEC . 2016 Aug 17;5(8):e88. (IF 5.776)

82. Liu N, Mei L, Fan X, Tang C, Ji X, Hu X, Shi W, Qian Y, Hussain M, Wu J, Wang C, Lin S, Wu X.
Phosphodiesterase 5/protein kinase G signal governs stemness of prostate cancer stem cells throughHippo pathway.
Cancer Lett . 2016 Aug 1;378(1):38-50. (IF 7.36)

83. Peng D, Wang X, Li Z, Zhang Y, Peng Y, Li Y, He X, Zhang X, Ma X, Huang L, Yan Y.
NO is involved in spermidine-induced drought tolerance in white clover via activation of antioxidant enzymes and genes.
Protoplasma . 2016 Sep;253(5):1243–54. (IF 2.751)

84. Peng D, Wang X, Li Z, Zhang Y, Peng Y, Li Y, He X, Zhang X, Ma X, Huang L, Yan Y.
NO is involved in spermidine-induced drought tolerance in white clover via activation of antioxidantenzymes and genes.
Protoplasma . 2016 Sep;253(5):1243-54. (IF 2.751)

85. Wang H, Guo Y, Liu L, Guan L, Wang T, Zhang L, Wang Y, Cao J, Ding W, Zhang F, Lu Z.
DDAH1 plays dual roles in PM2.5 induced cell death in A549 cells.
BBA-BIOMEMBRANES . 2016 Dec;1860(12):2793-801. (IF 3.411)

86. Wang YX, Xiang C, Liu B, Zhu Y, Luan Y, Liu ST, Qin KR.
A multi-component parallel-plate flow chamber system for studying the effect of exercise-induced wall shearstress on endothelial cells.
Biomed Eng Online . 2016 Dec 28;15(Suppl 2):154. (IF 2.059)

87. Huang G, Diao J, Yi H, Xu L, Xu J, Xu W.
Signaling pathways involved in HSP32 induction by hyperbaric oxygen in rat spinal neurons.
Redox Biol . 2016 Dec;10:108-118. (IF 9.986)

88. Zhai L, Xiao D, Sun C, Wu T, Han Z, Zhang X, Xu X, Wang Y.
Nitric oxide signaling is involved in the response to iron deficiency in the woody plant Malus xiaojinensis.
PLANT PHYSIOL BIOCH . 2016 Dec;109:515-524. (IF 3.72)

89. Meng J, Lv Z, Qiao X, Li X, Li Y, Zhang Y, Chen C.
The decay of Redox-stress Response Capacity is a substantive characteristic of aging: Revising the redoxtheory of aging.
Redox Biol . 2016 Dec 28;11:365-374. (IF 9.986)

90. Zhao W, Wu C, Li S, Chen X.
Adiponectin protects palmitic acid induced endothelial inflammation and insulin resistance via regulatingROS/IKKβ pathways.
Cytokine . 2016 Dec;88:167-176. (IF 2.952)

91. Wen J, Wu Y, Wei W, Li Z, Wang P, Zhu S, Dong W.
Protective effects of recombinant human cytoglobin against chronic alcohol-induced liver disease in vivoand in vitro.
SCI REP-UK . 2017 Jan 27;7:41647. (IF 3.998)

92. Wen J, Wu Y, Wei W, Li Z, Wang P, Zhu S, Dong W.
Protective effects of recombinant human cytoglobin against chronic alcohol-induced liverdisease in vivo and in vitro.
SCI REP-UK . 2017 Jan 27;7:41647. (IF 3.998)

93. Zong M, Bai L, Liu Y, Wang X, Zhang X, Huang X, Hang R, Tang B.
Antibacterial ability and angiogenic activity of Cu-Ti-O nanotube arrays.
MAT SCI ENG C-MATER . 2017 Feb 1;71:93-99. (IF 5.88)

94. Wang W, Li M, Wang L, Chen H, Liu Z, Jia Z, Qiu L, Song L.
The granulocytes are the main immunocompetent hemocytes in Crassostrea gigas.
Dev Comp Immunol . 2017 Feb;67:221-228. (IF 3.192)

95. Wang W, Li M, Wang L, Chen H, Liu Z, Jia Z, Qiu L, Song L.
The granulocytes arethe main immunocompetent hemocytes in Crassostrea gigas.
Dev Comp Immunol . 2017 Feb;67:221-228. (IF 3.192)

96. Xu X, Chen Y, Song J, Hou F, Ma X, Liu B, Huang F.
Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and preventsinsulin resistance in the endothelium.
Eur J Nutr . 2017 Mar 27. (IF 4.664)

97. Yi M, Bai H, Xue M, Yi H.
NOand H2O2 contribute to SO2 toxicity via Ca2+ signaling in Vicia faba guard cells.
ENVIRON SCI POLLUT R . 2017 Apr;24(10):9437-9446. (IF 3.056)

98. Meng J, Lv Z, Qiao X, Li X, Li Y, Zhang Y, Chen C.
The decay of Redox-stress Response Capacity is a substantive characteristic of aging: Revising the redox theory of aging.
Redox Biol . 2017 Apr;11:365-374. (IF 9.986)

99. Chen Y, Gao A, Bai L, Wang Y, Wang X, Zhang X, Huang X, Hang R, Tang B, Chu PK.
Antibacterial, osteogenic,and angiogenic activities of SrTiO3 nanotubes embedded with Ag2Onanoparticles.
MAT SCI ENG C-MATER . 2017 Jun 1;75:1049-1058. (IF 5.88)

100. Yin M, Tan S, Bao Y, Zhang Z.
Enhanced tumor therapy via drug co-delivery and in situ vascular-promoting strategy.
J Control Release . 2017 Jul 28;258:108-120. (IF 7.727)

101. Wang TT, Shi ZQ, Hu LB, Xu XF, Han FX, Zhou LG, Chen J.
Thymol Ameliorates Cadmium-Induced Phytotoxicity inthe Root of Rice (Oryza sativa) Seedling by Decreasing Endogenous Nitric Oxide Generation.
J AGR FOOD CHEM . 2017 Aug 30;65(34):7396-7405. (IF 4.192)

102. Dai X, Guo G, Zou P, Cui R, Chen W, Chen X, Yin C, He W, Vinothkumar R, Yang F, Zhang X, Liang G.
(S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROSindependent of MTH1.
J EXP CLIN CANC RES . 2017 Sep 7;36(1):120. (IF 7.068)

103. Li Y, Lu Y, Chen Q, Kang Y, Yu L.
Probing of peripheral blood mononuclear cells anchoring on TNF-alpha challenged-vascularendothelia in an in vitro model of the retinal microvascular.
Biomed Microdevices . 2017 Sep;19(3):54. (IF 2.176)

104. Han L, Zhang M, Liang X, Jia X, Jia J, Zhao M, Fan Y.
Interleukin-33 promotes inflammation-induced lymphangiogenesis via ST2/TRAF6-mediatedAkt/eNOS/NO signalling pathway.
SCI REP-UK . 2017 Sep 6;7(1):10602. (IF 3.998)

105. Geng YD, Zhang C, Lei JL, Yu P, Xia YZ, Zhang H, Yang L, Kong LY.
Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
Biochem Pharmacol . 2017 Oct 15;142:71-86. (IF 4.96)

106. Bai XL, Yang XY, Li JY, Ye-Li, Jia X, Xiong ZF, Wang YM, Jin S.
Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1loop.
ONCOTARGET . 2017 Oct 19;8(61):103985-103995. (IF 5.168)

107. Guo D, Murdoch CE, Xu H, Shi H, Duan DD, Ahmed A, Gu Y.
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SCI REP-UK . 2017 Nov 7;7(1):14749. (IF 3.998)

108. Yang H,Li X,Liu Y,Li X,Li X,Wu M,Lv X,Chunhua C,Ding X,Zhang Y
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CELL PHYSIOL BIOCHEM . 2018;46(2):765-780. (IF 5.5)

109. Cao L,Kong X,Lin S,Zhang S,Wang J,Liu C,Jiang X
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ARTIF CELL NANOMED B . 2018;46(sup3):S1-S17. (IF 3.343)

110. Zhang X, Li J, Wang X, Wang Y, Hang R, Huang X, Tang B, Chu PK.
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MAT SCI ENG C-MATER . 2018 Jan 1;82:110-120. (IF 5.88)

111. Pan Y, Chen J, Yu Y, Dai K, Wang J, Liu C.
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BIOMATER SCI-UK . 2018 Jan 30;6(2):431-439. (IF 6.183)

112. Shou X, Zhou R, Zhu L, Ren A, Wang L, Wang Y, Zhou J, Liu X, Wang B.
Emodin,A Chinese Herbal Medicine, Inhibits Reoxygenation-Induced Injury in Cultured HumanAortic Endothelial Cells by Regulating the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Endothelial Nitric Oxide Synthase (eNOS) Signaling Pathway.
MED SCI MONITOR . 2018 Feb 1;24:643-651. (IF 1.918)

113. Chao Y, Ye P, Zhu L, Kong X, Qu X, Zhang J, Luo J, Yang H, Chen S.
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J Cell Physiol . 2018 Feb;233(2):1384-1395. (IF 5.546)

114. Li K, Li Y, Mi J, Mao L, Han X, Zhao J.
Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS.
Int J Mol Med . 2018 Feb 6. (IF 3.098)

115. Zhang H, Wang Q, Gu J, Yin L, Liang S, Wu L, Xu H, Zhao C, Gu Y.
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Oncogene . 2018 Feb 20. (IF 7.971)

116. Xiao L, Dong JH, Teng X, Jin S, Xue HM, Liu SY, Guo Q, Shen W, Ni XC, Wu YM.
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J Hypertens . 2018 Mar;36(3):651-665. (IF 4.171)

117. Wang J,Li T,Feng J,Li L,Wang R,Cheng H,Yuan Y
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ENVIRON TOXICOL CHEM . 2018 Jun;60:128-137. (IF 3.152)

118. Xu X, Chen Y, Song J, Hou F, Ma X, Liu B, Huang F.
Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium.
Eur J Nutr. 2018 Jun;57(4):1563-1575. (IF 4.664)

119. Liu S,Hou X,Chen L,Hu H,Sun Q,Zhao F,Liu C
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J Cell Mol Med . 2018 Jul;22(7):3340-3352. (IF 4.486)

120. Luo W,Wang Y,Yang H,Dai C,Hong H,Li J,Liu Z,Guo Z,Chen X,He P,Li Z,Li F,Jiang J,Liu P,Li Z
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AGING-US . 2018 Jul 24;10(7):1722-1744. (IF 4.831)

121. Sun Z,Yi Z,Cui X,Chen X,Su W,Ren X,Li X
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Nanoscale . 2018 Jul 5;10(25):12109-12122. (IF 6.895)

122. Zhao Y,Yue C,Ding W,Li T,Xu JW,Zhao P,Ma H,Yu X
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BIORESOURCE TECHNOL . 2018 Oct;266:315-321. (IF 7.539)

123. Hou T,Li S,Zhang G,Li Y
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Int J Mol Med . 2018 Oct;42(4):2107-2119. (IF 3.098)

124. Wang YX,Liu HB,Li PS,Yuan WX,Liu B,Liu ST,Qin KR
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Cell Mol Bioeng. 2018 Oct 8;12(1):107-120. (IF 1.72)

125. Yu W,Gu Y,Chen P,Luo J,Liu P,Chao Y,Chen SL,Zhang H
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J Cell Physiol. 2019 Feb;234(2):1842-1850. (IF 5.546)

126. Chen X,Chen X,Zhang X,Wang L,Cao P,Rajamanickam V,Wu C,Zhou H,Cai Y,Liang G,Wang Y
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Redox Biol. 2019 Feb;21:101061. (IF 9.986)

127. Xu Y,Ren H,Liu J,Wang Y,Meng Z,He Z,Miao W,Chen G,Li X
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Nanoscale. 2019 Mar 21;11(12):5474-5488. (IF 6.895)

128. Bai L,Liu Y,Zhang X,Huang X,Yao X,Hang R,Tang B,Xiao Y
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Nanoscale. 2019 Mar 28;11(13):5920-5931. (IF 6.895)

129. Zheng Y,Dai Y,Liu W,Wang N,Cai Y,Wang S,Zhang F,Liu P,Chen Q,Wang Z
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J Cell Physiol. 2019 Apr;234(4):4277-4290. (IF 5.546)

130. Chu Q,Zhang S,Yu L,Li Y,Liu Y,Ye X,Zheng X
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Int J Biol Macromol. 2019 Jun 1;130:892-902. (IF 5.162)

131. Chen KL,Li L,Li CM,Wang YR,Yang FX,Kuang MQ,Wang GL
SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway.
Oxid Med Cell Longev. 2019 Jun 11;2019:3187972. (IF 5.076)

132. Niu X,Cao J,Zhang Y,Gao X,Cheng M,Liu Y,Wang W,Yuan Z
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Nanomedicine. 2019 Aug;20:102015. (IF 4.3)

133. Luo Y,Zhang Q,Ding J,Yu M,Jiang J,Yang F,Wang S,Wang A,Wang L,Wu S,Xia Y,Lu D
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BIOCHEM BIOPH RES CO. 2019 Aug 27;516(3):613-618. (IF 2.985)

134. Yang H,Zhu L,Gu Y,Kong X,Yan Liu,Chen M,Xie X,Luo J,Chen S
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Eur J Pharmacol. 2019 Aug 5;856:172413. (IF 3.263)

135. Feng T,Wan J,Li P,Ran H,Chen H,Wang Z,Zhang L
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Biomaterials. 2019 Sep;214:119213. (IF 10.317)

136. Zhou Z,Zhou X,Dong Y,Li M,Xu Y
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Mol Med Rep. 2019 Sep;20(3):2893-2901. (IF 2.1)

137. Huang H,Huang M,Lv W,Hu Y,Wang R,Zheng X,Ma Y,Chen C,Tang H
Inhibition of Trichophyton rubrum by 420-nm Intense Pulsed Light: In Vitro Activity and the Role of Nitric Oxide in Fungal Death.
Front Pharmacol. 2019 Oct 3;10:1143. (IF 4.225)

138. Lou K,Huang P,Ma H,Wang X,Xu H,Wang W
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Drug Chem Toxicol. 2019 Oct 31:1-9; (IF 2.405)

139. Jing M,Wang Y,Xu L
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Oxid Med Cell Longev. 2019 Oct 7;2019:6138723. (IF 5.076)

140. Li W,Yong J,Xu Y,Wang Y,Zhang Y,Ren H,Li X
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COLLOID SURFACE B. 2019 Nov 1;183:110453. (IF 4.389)

141. Wei G,Yang G,Wei B,Wang Y,Zhou S
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Acta Biomater. 2019 Dec;100:365-377. (IF 7.242)

142. Tian Y,Gong P,Wu Y,Chang S,Xu J,Yu B,Qi J
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143. Chen L,He W,Peng B,Yuan M,Wang N,Wang J,Lu W,Wang T
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BIOCHEM BIOPH RES CO. 2019 Dec 10;520(3):580-585. (IF 2.985)

144. Zhong X,Zhang M,Tian Z,Wang Q,Wang Z
The Study of Enhanced High-Intensity Focused Ultrasound Therapy by Sonodynamic N2O Microbubbles.
Nanoscale Res Lett. 2019 Dec 16;14(1):381. (IF 3.581)

145. Zhuo Ma,Can Wang,Chang Liu,Dong-Ying Yan,Xuan Tan,Kuan Liu,Meng-Jiao Jing,Yu Deng,Wei Liu,Bin Xu
Manganese induces autophagy dysregulation: The role of S-nitrosylation in regulating autophagy related proteins in vivo and in vitro
Sci Total Environ. 2020 Jan 1;698:134294.;doi: 10.1016/j.scitotenv.2019.134294.

146. Yixiu Zhao,Jiuxin Zhu,Hangfei Liang,Shuang Yang,Yannan Zhang,Weina Han,Chao Chen,Na Cao,Aruhan,Peiqiang Liang,Xing Du,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang
Kang Le Xin Reduces Blood Pressure Through Inducing Endothelial-Dependent Vasodilation by Activating the AMPK-eNOS Pathway
Front Pharmacol. 2020 Jan 22;10:1548.;doi: 10.3389/fphar.2019.01548.

147. Wen-Xuan Li,Fei Wang,Yun-Qian Zhu,Li-Mei Zhang,Zhen-Hua Zhang,Xiao-Ming Wang
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148. Wu W,Chen M,Luo T,Fan Y,Zhang J,Zhang Y,Zhang Q,Sapin-Minet A,Gaucher C,Xia X
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Acta Biomater. 2020 Feb;103:259-271. (IF 7.242)

149. Shoufei Yang,Wei Cheng,Xiaolan Li,Fan Liang,Ren Zhou,Hui Wang,Yan Feng,Yan Wang
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Toxicology. 2020 Feb 28;432:152380.;doi: 10.1016/j.tox.2020.152380.

150. Yang Yang,Shaoqing Li,Yi Qu,Xue Wang,Wei An,Zhilin Li,Zhengxue Han,Lizheng Qin
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151. Pan Huang,Baocai Xu,Xuefei Shao,Conggui Chen,Wu Wang,Peijun Li
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152. Longlong Gong,Zhengzhi Zou,Lei Huang,Shuang Guo,Da Xing
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153. Ying Lan,Xiaohui Zhu,Ming Tang,Yihan Wu,Jing Zhang,Jinliang Liu,Yong Zhang
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154. Fang Liu,Shaohong Fang,Xinxin Liu,Ji Li,Xuedong Wang,Jinjin Cui,Tao Chen,Zhaoying Li,Fan Yang,Jiangtian Tian,Hulun Li,Li Yin,Bo Yu
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155. Ping Liu,Yidan Wang,Yang Liu,Fengping Tan,Jining Li,Nan Li
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156. Yanan Xu,Cheng Qu,Xia Sun,Zhifei Jia,Ming Xue,Haipeng Zhao,Xuguo Zhou
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157. Huiting Luo,Peijun Li,Hongwei Zhang,Xinping Diao,Baohua Kong
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TRIM16 protects human periodontal ligament stem cells from oxidative stress-induced damage via activation of PICOT
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