Carboxy-PTIO (一氧化氮清除剂)(S1547)

Carboxy-PTIO (一氧化氮清除剂)

产品编号: S1547

产品包装:50mg
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5mg 50mg

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2605.00 10

价格: ¥ 2605.00

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产品编号 产品名称 产品包装 产品价格
S1546 Carboxy-PTIO (一氧化氮清除剂) 5mg 436.00元
S1547 Carboxy-PTIO (一氧化氮清除剂) 50mg 2605.00元

Carboxy-PTIO,是一种常用的一氧化氮清除剂,可以用于抑制一氧化氮信号通路。本Carboxy-PTIO为钾盐(Carboxy-PTIO potassium salt)。carboxy-PTIO可以和NO反应生成carboxy-PTI衍生物,同时产生亚硝酸盐或硝酸盐,从而起到清除NO的作用。
Carboxy-PTIO的分子量为315.39,分子式为C14H16KN2O4,CAS Number:148819-94-7。本产品为进口分装,纯度大于98%。
Carboxy-PTIO水溶性很好,溶解度大于20mg/ml,可溶于一些常见缓冲液如PBS等,也可溶于无水乙醇、甲醇、DMSO、二甲基甲酰胺。
包装清单:

产品编号 产品名称 包装
S1547 Carboxy-PTIO(一氧化氮清除剂) 50mg
说明书 1份

保存条件:
-20℃保存。
注意事项:
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
1. Carboxy-PTIO常见使用浓度为0.1-10mM。实际的最佳工作浓度请参考相关文献,或根据实验目的,以及所培养的特定细胞和组织,通过实验进行摸索和优化。

Carboxy-PTIO (一氧化氮清除剂)(S1547)

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使用本产品的文献:

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Chondroitin sulfate N-acetylgalactosaminyltransferase-2 contributes to the replication of infectious bursal disease virus via interaction with the capsid protein VP2.
VIRUSES-BASEL . 2015 Mar 23;7(3):1474-91. (IF 3.816)

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The Anti-apoptotic Effect of Polypeptide from Chlamys farreri (PCF) in UVB-Exposed HaCaT Cells Involves Inhibition of iNOS and TGF-β1.
Cell Biochem Biophys . 2015 Mar;71(2):1105-15. (IF 2.073)

4. Song LJ, Luo H, Fan WH, Wang GP, Yin XR, Shen S, Wang J, Jin Y, Zhang W, Gao H, Liu Q, Wang WL, Feng B, Yu CX.
Oxadiazole-2-oxides may have other functional targets, in addition to SjTGR, through which they causemortality in Schistosoma japonicum.
PARASITE VECTOR . 2016 Jan 20;9:26. (IF 2.824)

5. Guo Y, Deng Y, Huang Z, Luo Q, Peng Y, Chen J, Jiang H, Ye J, Li J.
EBP50 induces apoptosis in macrophages by upregulating nitric oxide production to eliminate intracellularMycobacterium tuberculosis.
SCI REP-UK . 2016 Jan 5;6:18961. (IF 3.998)

6. An XZ, Zhao ZG, Luo YX, Zhang R, Tang XQ, Hao D, Zhao X, Lv X, Liu D.
Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer.
ONCOTARGET . 2016 Apr 26;7(17):24719-33. (IF 5.168)

7. Chen XH, Liu SR, Peng B, Li D, Cheng ZX, Zhu JX, Zhang S, Peng YM, Li H, Zhang TT, Peng XX.
Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens.
Front Immunol . 2017 Mar 6;8:207. (IF 5.085)

8. Liu L,Huang Z,Chen J,Wang J,Wang S
Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells.
J EXP CLIN CANC RES . 2018 Jul 9;37(1):142. (IF 7.068)

9. Liu L,Huang Z,Chen J,Wang J,Wang S
Protein phosphatase 2A mediates JS-K-induced apoptosis by affecting Bcl-2 family proteins in human hepatocellular carcinoma HepG2 cells.
J Cell Biochem . 2018 Aug;119(8):6633-6643. (IF 4.237)

10. Huang Z,Liu L,Chen J,Cao M,Wang J
JS-K as a nitric oxide donor induces apoptosis via the ROS/Ca2+/caspase-mediated mitochondrial pathway in HepG2 cells.
Biomed Pharmacother . 2018 Nov;107:1385-1392. (IF 4.545)

11. Shang XY,Chen JJ,Song XY,Wang W,Chen Y,Yao GD,Song SJ
Daphnegiravone D from Daphne giraldii Nitsche induces p38-dependent apoptosis via oxidative and nitrosative stress in hepatocellular carcinoma cells.
Biomed Pharmacother . 2018 Nov;107:1426-1433. (IF 4.545)

12. Wang G,Zhao H,Zheng B,Li D,Yuan Y,Han Q,Tian Z,Zhang J
TLR2 Promotes Monocyte/Macrophage Recruitment Into the Liver and Microabscess Formation to Limit the Spread of Listeria Monocytogenes.
Front Immunol. 2019 Jun 26;10:1388. (IF 5.085)

13. Mengwen Xue,Liang Han,Weikun Qian,Jie Li,Tao Qin,Ying Xiao,Qingyong Ma,Jiguang Ma,Xin Shen
Nitric Oxide Stimulates Acute Pancreatitis Pain via Activating the NF- κ B Signaling Pathway and Inhibiting the Kappa Opioid Receptor
Oxid Med Cell Longev. 2020 May 7;2020:9230958.;doi: 10.1155/2020/9230958.

14. Fujun Jin,Rongze Wang,Yexuan Zhu,Jingyi Chen,Wei Cao,Yiliang Wang,Yanting Wu,Xiaowei Song,Yunsheng Huang,Jun Dong,Zhe Ren
A novel quinolinylmethyl substituted ethylenediamine compound exerts anti-cancer effects via stimulating the accumulation of reactive oxygen species and NO in hepatocellular carcinoma cells
Eur J Pharmacol. 2020 Oct 15;885:173497.;doi: 10.1016/j.ejphar.2020.173497.