世界*实验材料供应商 Schircks上海金畔生物为其中国代理， Schircks在一直是行业的*,一直为广大科研客户提供zui为的产品和服务,上海金畔生物一直秉承为中国科研客户带来的产品，的服务，Schircks就是为了给广大科研客户带来更加完善的产品和服务,您的满意将是我们zui大的收获
Schircks中国代理, Schircks上海代理， Schircks北京代理，Schircks广东代理， Schircks江苏代理Schircks湖北代理,Schircks天津,Schircks黑龙江代理,Schircks内蒙古代理,Schircks吉林代理,Schircks福建代理,Schircks江苏代理, Schircks浙江代理, Schircks四川代理,
Schircks Laboratories由B. Schircks博士在瑞士成立，1980合成蝶啶。该公司是独立经营的。schircks实验室已经停止生产四氢生物蝶呤。BIOMARIN已经接管了美国市场，默克雪兰诺公司欧洲市场。他们将继续扩大。他们是负责供应（盐酸沙丙蝶呤呤）片剂（含量）。
超过100的schircks实验室其他蝶啶类化合物主要用于科学和临床诊断应用的合成。我们不断开发和改进合成，并开始新的合成，以满足世界各地的研究和开发小组的需求。
世界*实验材料供应商 Schircks上海金畔生物为其中国代理， Schircks在一直是行业的*,一直为广大科研客户提供zui为的产品和服务,上海金畔生物一直秉承为中国科研客户带来的产品，的服务，Schircks就是为了给广大科研客户带来更加完善的产品和服务,您的满意将是我们zui大的收获
Schircks中国代理, Schircks上海代理， Schircks北京代理，Schircks广东代理， Schircks江苏代理Schircks湖北代理,Schircks天津,Schircks黑龙江代理,Schircks内蒙古代理,Schircks吉林代理,Schircks福建代理,Schircks江苏代理, Schircks浙江代理, Schircks四川代理,
Schircks Laboratories由B. Schircks博士在瑞士成立，1980合成蝶啶。该公司是独立经营的。schircks实验室已经停止生产四氢生物蝶呤。BIOMARIN已经接管了美国市场，默克雪兰诺公司欧洲市场。他们将继续扩大。他们是负责供应（盐酸沙丙蝶呤呤）片剂（含量）。
超过100的schircks实验室其他蝶啶类化合物主要用于科学和临床诊断应用的合成。我们不断开发和改进合成，并开始新的合成，以满足世界各地的研究和开发小组的需求。
D A T A S H E E T
4-Ami0-methylpteroylpolyglutamates
Product No.'s 16.412 and 16.417
|
Product number |
|
|
|
|
|
16.412 |
|
|
16.417 |
|
|
|||||||||
|
Description |
|
|
|
|
|
|
|
yellow-orange powder |
|
yellow-orange powder |
||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||
|
Solubility in H2O |
|
|
|
|
|
|
|
|
very soluble |
|
|
very soluble |
||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
||||||||
|
pH of a 1 mM solution in |
|
|
|
|
5.7 |
|
|
5.9 |
|
|
|
|||||||||
|
water |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
HPLC |
|
column |
|
|
|
Waters Spherisorb S5 ODS1 |
|
Waters Spherisorb S5 ODS1 |
||||||||||||
|
Conditions |
|
|
|
|
|
|
|
|
|
|
4.6×150 mm |
|
|
4.6×150 mm |
||||||
|
|
|
eluant |
|
|
10 mM Na2HPO4 pH 7.0 / Methanol |
|
10 mM Na2HPO4 pH 6.0 |
|||||||||||||
|
|
|
|
|
|
|
|
|
(19:1) |
|
|
|
|
|
|
|
|
|
|||
|
|
|
flow rate |
|
|
|
|
|
|
|
1.0 ml/min |
|
|
1.0 ml/min |
|||||||
|
|
|
wavelength |
|
|
|
|
|
|
|
254 nm |
|
|
|
254 nm |
||||||
|
|
|
solution |
|
|
|
|
|
|
|
0.6 mg/ml H2O |
|
|
1.4 mg/ml H2O |
|||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|||||||||
|
Purity: HPLC |
|
|
|
|
|
|
|
97.0% – 99.5% |
|
|
97.0% – 99.5% |
|||||||||
|
|
|
|
|
|
|
|
||||||||||||||
|
Stability |
|
powder |
|
|
APA-Glun substances are light sensitive |
and very hygroscopic. |
||||||||||||||
|
|
|
solutions |
|
|
No degradation was observed in a |
|
1 mM solution in water left open |
|||||||||||||
|
|
|
|
|
|
|
1 mM solution in water left open for |
|
degrades at rate 0.11% / 3 days. |
||||||||||||
|
|
|
|
|
|
|
3 days. |
|
|
|
|
|
|
|
|
|
|||||
|
|
|
|
|
|
|
|
|
|||||||||||||
|
Storage |
|
|
|
|
|
Keep the powder dry in vials at –20°C |
or colder. These compounds can be |
|||||||||||||
|
|
|
|
|
|
|
transported without the use of dry ice. In tightly closed vials they are stable |
||||||||||||||
|
|
|
|
|
|
|
at ambient temperature for several weeks. |
|
|
|
|
||||||||||
|
|
|
|
|
|
||||||||||||||||
|
Safety Information |
|
|
|
Methotrexate is toxic1) and probably also its derivatives. Our products are |
||||||||||||||||
|
|
|
|
|
|
|
sold for laboratory use only. |
|
|
|
|
|
|
|
|
||||||
|
|
|
|
|
|
|
|||||||||||||||
|
Literature |
|
|
|
|
1)Please refer to entries for folic acid and methotrexate in the Merck Index. |
|||||||||||||||
|
|
|
|
|
|
|
2)Godwin H.A., et al, The Synthesis of Biologically Active Pteroyloligo-γ-L- |
||||||||||||||
|
|
|
|
|
|
|
glutamates (Folic Acid Conjugates). J. Biol. Chem., 247, (1972), 2266-2271 |
||||||||||||||
|
|
|
|
|
|
|
(UV-absorption). |
|
|
|
|
|
|
|
|
|
|||||