Fluo-3 AM (钙离子荧光探针, 5mM)(S1056)

Fluo-3 AM (钙离子荧光探针, 5mM)

产品编号: S1056

产品包装:20μl
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20μl

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568.00 10

价格: ¥ 568.00

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S1056 Fluo-3 AM (钙离子荧光探针, 5mM) 20μl 568.00元

Fluo-3 AM是最常用的检测细胞内钙离子浓度的荧光探针之一。分子式为C51H50Cl2N2O23,分子量为1129.85。
Fluo-3和Fura-2相比,其优点是:一方面可以被氩离子激光(argon-ion laser)的488nm激发光激发,便于检测;另一方面,Fluo-3和钙离子结合后荧光变化更强,即对钙离子浓度变化的检测更加灵敏;同时,Fluo-3和钙离子的结合能力较弱,这样可以比Fura-2检测到细胞内更高浓度的钙离子水平;此外,对于细胞内的钙离子的即时变化反应得更加准确,减小了因为和钙离子解离速度慢而导致的荧光变化滞后。
本Fluo-3 AM (钙离子荧光探针) 是配制于无水DMSO (anhydrous DMSO)中的储存液,浓度为5mM
Fluo-3 AM是一种可以穿透细胞膜的荧光染料。Fluo-3 AM的荧光非常弱,其荧光不会随钙离子浓度升高而增强。Fluo-3 AM进入细胞后可以被细胞内的酯酶剪切形成Fluo-3,从而被滞留在细胞内。Fluo-3可以和钙离子结合,结合钙离子后可以产生较强的荧光,最大激发波长为506nm,最大发射波长为526nm。实际检测时推荐使用的激发波长为488nm左右,发射波长为525-530nm。Fluo-3的激发光谱和发射光谱参考下图。

Fluo-3 AM (钙离子荧光探针, 5mM)(S1056)

用于细胞内钙离子检测时,Fluo-3 AM的常用浓度为0.5-5μM。通常用含有0.5-5μM的Fluo-3 AM适当溶液和细胞一起在20-37℃孵育15-60分钟进行荧光探针装载,随后适当洗涤,洗涤后可以考虑适当再孵育20-30分钟以确保Fluo-3 AM在细胞内完全转变成Fluo-3。
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产品编号 产品名称 包装
S1056 Fluo-3 AM(钙离子荧光探针, 5mM) 20μl
说明书 1份

保存条件:
-20℃避光保存,6个月有效。
注意事项:
本Fluo-3 AM在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
荧光染料均存在淬灭问题,请尽量注意避光,以减缓荧光淬灭。
      本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Fluo-3 AM (钙离子荧光探针, 5mM)(S1056)

相关产品请点击如下按钮:
钙离子等检测
小分子荧光探针

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1. Park S, Ahn IS, Kwon DY, Ko BS, Jun WK.
Increased Glucagon-like peptide-1 secretion may be involved in anti-diabetic effects of ginsenosides.
BIOSCI BIOTECH BIOCH . 2008 Nov;72(11):2815-23. (IF 1.516)

2. Li H, Wang L, Ye L, Mao Y, Xie X, Xia C, Chen J, Lu Z, Song J.
Influence of Pseudomonas aeruginosa quorum sensing signal molecule N-(3-oxododecanoyl) homoserine lactone on mast cells.
MED MICROBIOL IMMUN . 2009 May;198(2):113-21. (IF 1.961)

3. Kuang CY, Yu Y, Guo RW, Qian DH, Wang K, Den MY, Shi YK, Huang L.
Silencing stromal interaction molecule 1 by RNA interference inhibits the proliferation andmigration of endothelial progenitor cells.
BIOCHEM BIOPH RES CO . 2010;398(2):315-20. (IF 2.985)

4. Shi Y, Song M, Guo R, Wang H, Gao P, Shi W, Huang L.
Knockdown of stromal interaction molecule 1 attenuates hepatocyte growth factor-inducedendothelial progenitor cell proliferation.
EXP BIOL MED . 2010 Mar;235(3):317-25. (IF 3.139)

5. Li C, Sun Y, Yi K, Ma Y, Sun Y, Zhang W, Zhou X.
Detection of nerve growth factor (NGF) and its specific receptor (TrkA) in ejaculated bovine sperm, and the effects of NGF on sperm function.
Theriogenology . 2010 Dec;74(9):1615-22. (IF 2.094)

6. Jin H, Zhong X, Wang Z, Huang X, Ye H, Ma S, Chen Y, Cai J.
Sonodynamic effects of hematoporphyrin monomethyl ether on CNE-2 cells detected by atomicforce microscopy.
J Cell Biochem . 2011 Jan;112(1):169-78. (IF 4.237)

7. Wang M, Ruan Y, Chen Q, Li S, Wang Q, Cai J.
Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca2+ concentration.
Eur J Pharmacol . 2011 Jan 10;650(1):41-7. (IF 3.263)

8. Li X, Ye X, Li X, Sun X, Liang Q, Tao L, Kang X, Chen J.
Salidroside protects against MPP+-induced apoptosis in PC12 cells by inhibiting the NO pathway.
Brain Res . 2011 Mar 25;1382:9-18. (IF 2.733)

9. Yang F, Zhang M, He W, Chen P, Cai X, Yang L, Gu N, Wu J.
Controlled release of Fe3O4 nanoparticles in encapsulated microbubbles to tumor cells viasonoporation and associated cellular bioeffects.
Small . 2011 Apr 4;7(7):902-10. (IF 11.459)

10. Jiang S, Zu Y, Wang Z, Zhang Y, Fu Y.
Involvement of mitochondrial permeability transition pore opening in 7-xylosyl-10-deacetylpaclitaxel-induced apoptosis.
Planta Med . 2011 Jul;77(10):1005-12. (IF 2.687)

11. Gao X, Luo Z, Xiang T, Wang K, Li J, Wang P.
Dihydroartemisinin induces endoplasmic reticulum stress-mediated apoptosis in HepG2 humanhepatoma cells.
TUMORI . 2011 Nov-Dec;97(6):771-80. (IF 1.233)

12. Tan Q, Li Y, Wu J, Mei H, Zhao C, Zhang J.
An optimized molecular inclusion complex of diferuloylmethane: enhanced physical properties and biologicalactivity.
INT J NANOMED . 2012;5:5385-93. (IF 5.115)

13. Zhang HY, Wang WX,Yin H, Zhao XM, Du YG.
Oligochitosan induces programmed cell death in tobacco suspension cells.
Carbohydrate Polymers .2012Feb;87(3):2270-8. (IF 6.044)

14. Zhao L, Ju D, Gao Q, Zheng X, Yang G.
Over-expression of Nkx2.5 and/or cardiac α-actin inhibit the contraction ability of ADSCs-derivedcardiomyocytes.
Mol Biol Rep . 2012 Mar;39(3):2585-95. (IF 1.402)

15. Che T, Sun H, Li J, Yu X, Zhu D, Xue B, Liu K, Zhang M, Kunze W, Liu C.
Oxytocin hyperpolarizes cultured duodenum myenteric intrinsic primary afferent neurons by opening BK(Ca) channels through IP3 pathway.
J Neurochem . 2012 May;121(4):516-25. (IF 4.066)

16. Zhang J, Song W, Guo J, Zhang J, Sun Z, Ding F, Gao M.
Toxic effect of different ZnO particles on mouse alveolar macrophages.
J Hazard Mater . 2012 Jun 15;219-220:148-55. (IF 9.038)

17. Zhang L, Li K, Bing Ma L, Gong SB, Wang GY, Liu Y, Ji XY, Xu L, Liu SK, Chen P, Ouyang RY, Xiang XD.
Effects and Mechanism of Arsenic Trioxide on Reversing the Asthma Pathologies Including Th17-IL-17 Axis in a Mouse Model.
IRAN J ALLERGY ASTHM . 2012 Jun;11(2):133-45. (IF 1.109)

18. Jin H, Yang P, Cai J, Wang J, Liu M.
Photothermal effects of folate-conjugated Au nanorods on HepG2 cells.
APPL MICROBIOL BIOT . 2012 Jun;94(5):1199-208. (IF 3.53)

19. Li SP, Xie WL, Cai HH, Cai JY, Yang PH.
Hydroxyl radical scavenging mechanism of human erythrocytes by quercetin-germanium (IV)complex.
Eur J Pharm Sci . 2012 Aug 30;47(1):28-34. (IF 3.616)

20. Li XY, Jing CQ, Zang XY, Yang S, Wang JJ.
Toxic cytological alteration and mitochondrial dysfunction in PC12 cells induced by 1-octyl-3-methylimidazolium chloride.
Toxicol In Vitro . 2012 Oct;26(7):1087-92. (IF 2.959)

21. Lu N, Zhan M, Gao C, Wu G, Zhang H.
I4, a new synthetic sulfonylurea compound, inhibits the action of TXA2 in vivo and in vitro on platelets and aorta vascular smooth muscle.
Thromb Res . 2012 Oct;130(4):e209-15. (IF 2.869)

22. Liang D, Zhou Q, Zhang J, Gong W, Xu C, Li B, Wang Y, Li J.
A novel chenodeoxycholic acid-verticinone ester induces apoptosis and cell cycle arrest in HepG2 cells.
Steroids . 2012 Nov;77(13):1381-90. (IF 1.948)

23. Zhang H, Shao D, Wu Y, Cai C, Hu C, Shou X, Dai B, Ye B, Wang M, Jia X.
Apoptotic responses of Carassius auratus lymphocytes to nodularin exposure in vitro.
FISH SHELLFISH IMMUN . 2012 Dec;33(6):1229-37. (IF 3.298)

24. Ouyang JS, Li YP, Li CY, Cai C, Chen CS, Chen SX, Chen YF, Yang L, Xie YP.
Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelialcells.
FREE RADICAL RES . 2012 Dec;46(12):1437-45. (IF 2.839)

25. Tan Q, Wu J, Li Y, Mei H, Zhao C, Zhang J.
A supermolecular curcumin for enhanced antiproliferative and proapoptotic activities: molecular characteristics,computer modeling and in vivo pharmacokinetics.
Nanotechnology . 2013 Jan 25;24(3):035102. (IF 3.551)

26. Li Z, Pan X, Wang T, Wang PN, Chen JY, Mi L.
Comparison of the killing effects between nitrogen-doped and pure TiO2 on HeLa cells with visible lightirradiation.
Nanoscale Res Lett . 2013 Feb 22;8(1):96. (IF 3.581)

27. Pi J, Jin H, Liu R, Song B, Wu Q, Liu L, Jiang J, Yang F, Cai H, Cai J.
Pathway of cytotoxicity induced by folic acid modified selenium nanoparticles in MCF-7 cells.
APPL MICROBIOL BIOT . 2013 Feb;97(3):1051-62. (IF 3.53)

28. Zhu XL, Qin XQ, Xiang Y, Tan YR, Qu XP, Liu HJ.
Adipokine adiponectin is a potential protector to human bronchial epithelial cell for regulating proliferation, wound repair and apoptosis: comparison with leptin and resistin.
Peptides . 2013 Feb;40:34-41. (IF 2.843)

29. Jiang L, Lan T, Chen Y, Sang J, Li Y, Wu M, Tao Y, Wang Y, Qian H, Gu L.
PKG II inhibits EGF/EGFR-induced migration of gastric cancer cells.
PLoS One . 2013 Apr 16;8(4):e61674. (IF 2.74)

30. Ma G, Zhou J, Tian C, Jiang D, Fang D, Chen H.
Luminol electrochemiluminescence for the analysis of active cholesterol at the plasma membrane in singlemammalian cells.
Anal Chem . 2013 Apr 16;85(8):3912-7. (IF 6.785)

31. Li M, Tan SY, Zhang J, You HX.
Effects of paeonol on intracellular calcium concentration and expression of RUNX3 in LoVo human colon cancercells.
Mol Med Rep . 2013 May;7(5):1425-30. (IF 2.1)

32. Chen Y, Chen JW, Zhai JH, Wang Y, Wang SL, Li X.
Antitumor activity and toxicity relationship of annonaceous acetogenins.
Food Chem Toxicol . 2013 May 24;58C:394-400. (IF 4.679)

33. Yang D, Lü X, Hong Y, Xi T, Zhang D.
The molecular mechanism of mediation of adsorbed serum proteins to endothelial cells adhesion and growth onbiomaterials.
Biomaterials . 2013 Jul;34(23):5747-58. (IF 10.317)

34. Xu M, Lu N, Zhang H, Dai Q, Wei L, Li Z, You Q, Guo Q.
Wogonin induced cytotoxicity in human hepatocellular carcinoma cells by activation of unfolded protein responseand inactivation of AKT.
Hepatol Res . 2013 Aug;43(8):890-905. (IF 3.165)

35. Liang S, Su WW, Wang YG, Peng W, Nie YC, Li PB.
Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal liver cell apoptosis.
Int J Mol Med . 2013 Aug;32(2):323-30. (IF 3.098)

36. Zhu K,Guo X, Guo X, Peng W, Zhou H.
Protective effects of wheat germ protein isolate hydrolysates (WGPIH) against hydrogen peroxide-induced oxidative stress in PC12 cells.
Food Research International .2013 Aug;53(1):297-303. (IF 3.579)

37. Xin J, Zhan Y, Liu M, Hu H, Xia L, Nie Y, Wu K, Liang J, Tian J.
ApoG2 induces ER stress-dependent apoptosis in gastric cancer cells in vitro and its real-time evaluation bybioluminescence imaging in vivo.
Cancer Lett . 2013 Aug 19;336(2):260-9. (IF 7.36)

38. Chen Z, Pan X, Georgakilas AG, Chen P, Hu H, Yang Y, Tian S, Xia L, Zhang J, Cai X,Ge J, Yu K, Zhuang J.
Tetramethylpyrazine (TMP) protects cerebral neurocytes and inhibits glioma by down regulating chemokinereceptor CXCR4 expression.
Cancer Lett . 2013 Aug 19;336(2):281-9. (IF 7.36)

39. Chen G, Zhang P, Huang T, Yu W, Lin J, Li P, Chen K.
Polysaccharides from Rhizopus nigricans mycelia induced apoptosis and G2/M arrest in BGC-823 cells.
Carbohydrate Polymers . 2013 Sep 12;97(2):800-8. (IF 6.044)

40. Zhang L, Liu J, Wang X, Li Z, Zhang X, Cao P, She X, Dai Q, Tang J, Liu Z.
Upregulation of cytoskeleton protein and extracellular matrix protein induced by stromal-derived nitric oxide promotes lung cancer invasion and metastasis.
Curr Mol Med . 2014;14(6):762-71. (IF 1.6)

41. Tong J, Zhou XD, Perelman JM, Kolosov VP.
Effect of epithelium ATP release on cyclic pressure-induced airway mucus secretion.
BIOSCIENCE REP . 2014 Feb 1;34(1). pii: e00088. (IF 2.942)

42. Tian J, Cheng J, Zhang J, Ye L, Zhang F, Dong Q, Wang H, Fu F.
Protection of pyruvate against glutamate excitotoxicity is mediated by regulating DAPK1 protein complex.
PLoS One . 2014 Apr 22;9(4):e95777. (IF 2.74)

43. Wu J, Chen W, Yin Y, Zheng Z, Zou G.
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Biometals . 2014 Jun;27(3):445-58. (IF 2.479)

44. Zhang S, Nie S, Huang D, Huang J, Feng Y, Xie M.
Ganoderma atrum polysaccharide evokes antitumor activity via cAMP-PKA mediated apoptotic pathway and down-regulation of Ca(2+)/PKC signal pathway.
Food Chem Toxicol . 2014 Jun;68:239-46. (IF 4.679)

45. Xu SY, Hu YF, Li WP, Wu YM, Ji Z, Wang SN, Li K, Pan SY.
Intermittent hypothermia is neuroprotective in an in vitro model of ischemic stroke.
Int J Biol Sci . 2014 Jul 29;10(8):873-81. (IF 4.858)

46. Ding Y, Dai X, Zhang Z, Jiang Y, Ma X, Cai X, Li Y.
Proanthocyanidins protect against early diabetic peripheral neuropathy by modulating endoplasmic reticulum stress.
J Nutr Biochem . 2014 Jul;25(7):765-72. (IF 4.873)

47. Guo Y, Wang W, Dong Y, Zhang Z, Zhou Y, Chen G.
Carbon disulfide induces rat testicular injury via mitochondrial apoptotic pathway.
Chemosphere . 2014 Aug;108:367-75. (IF 5.778)

48. Yang Y, Li D, Katirai F, Zhang B, Xu Y, Xiong P, Gong F, Zheng F.
Basophil activation through ASGM1 stimulation triggers PAF release and anaphylaxis-like shock in mice.
Eur J Immunol . 2014 Aug;44(8):2468-77. (IF 4.404)

49. Duan Y, Wang Z, Zhang H, He Y, Fan R, Cheng Y, Sun G, Sun X.
Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, MAPK pathway activation and decreased CREB phosphorylation in mice hippocampus: reversal by procyanidins extracted from the lotus seedpod.
Food Funct . 2014 Sep;5(9):2289-97. (IF 4.171)

50. Zhao Y, Zhou J, Xing D.
Phytochrome B-mediated activation of lipoxygenase modulates an excess red light-induced defence response in Arabidopsis.
J Exp Bot . 2014 Sep;65(17):4907-18. (IF 5.908)

51. Li S, Zhang S, Jin X, Tan X, Lou J, Zhang X, Zhao Y.
Singly protonated dehydronorcantharidin silver coordination polymer induces apoptosis of lung cancer cells via reactive oxygen species-mediated mitochondrial pathway.
Eur J Med Chem . 2014 Oct 30;86:1-11. (IF 5.572)

52. Zhong L, Wang L, Xu L, Liu Q, Jiang L, Zhi Y, Lu W, Zhou P.
The role of nitric oxide synthase signaling pathway in the Zn-induced cellular responses in MCF-7 cells.
ENVIRON TOXICOL CHEM . 2014 Nov;38(3):783-91. (IF 3.152)

53. Wang Y, Yuan L, Yao C, Ding L, Li C, Fang J, Sui K, Liu Y, Wu M.
A combined toxicity study of zinc oxide nanoparticles and vitamin C in food additives.
Nanoscale . 2014 Dec 21;6(24):15333-42. (IF 6.895)

54. Lu M, Sun L, Zhou J, Zhao Y, Deng X.
Dihydroartemisinin-Induced Apoptosis is Associated with Inhibition of Sarco/Endoplasmic Reticulum Calcium ATPase Activity in Colorectal Cancer.
Cell Biochem Biophys . 2015;73(1):137-45. (IF 2.073)

55. Zhong L, Wang L, Xu L, Liu Q, Jiang L, Zhi Y, Lu W, Zhou P.
The role of NOS-mediated ROS accumulation in an early phase Cu-induced acute cytotoxicity in MCF-7 cells.
Biometals . 2015 Feb;28(1):113-22. (IF 2.479)

56. Li M, Wang N, Gong HQ, Li WZ, Liao XH, Yang XL, He HP, Cao DS, Zhang TC.
Ca2⁺ signal-induced cardiomyocyte hypertrophy through activation of myocardin.
Gene . 2015 Feb 15;557(1):43-51. (IF 2.984)

57. Zhong L, Wang L, Xu L, Liu Q, Jiang L, Zhi Y, Lu W, Zhou P.
The role of NOS-mediated ROS accumulation in an early phase Cu-induced acute cytotoxicity in MCF-7 cells.
Biometals . 2015 Feb;28(1):113-22. (IF 2.479)

58. Hu XL, Gao LY, Niu YX, Tian X, Wang J, Meng WH, Zhang Q, Cui C, Han L, Zhao QC.
Neuroprotection by Kukoamine A against oxidative stress may involve N-methyl-D-aspartate receptors.
BBA-BIOMEMBRANES . 2015 Feb;1850(2):287-98. (IF 3.411)

59. Huang S, Ren Y, Wang P, Li Y, Wang X, Zhuang H, Fang R, Wang Y, Liu N, Hehir M, Zhou JX.
Transcription Factor CREB is Involved in CaSR-mediated Cytoskeleton Gene Expression.
ANAT REC . 2015 Mar;298(3):501-12. (IF 1.634)

60. Zhong L, Wang L, Xu L, Liu Q, Jiang L, Zhi Y, Lu W, Zhou P.
The role of nitric oxide synthase in an early phase Cd-induced acute cytotoxicity in MCF-7 cells.
Biol Trace Elem Res . 2015 Mar;164(1):130-8. (IF 2.639)

61. Zeng Z, Leng T, Feng X, Sun H, Inoue K, Zhu L, Xiong ZG.
Silencing TRPM7 in mouse cortical astrocytes impairs cell proliferation and migration via ERK and JNK signaling pathways.
PLoS One . 2015 Mar 23;10(3):e0119912. (IF 2.74)

62. Liu Z, Zhou Z, Wang L, Jiang S, Wang W, Zhang R, Song L.
The immunomodulation mediated by a delta-opioid receptor for [Met(5)]-enkephalin in oyster Crassostrea gigas.
Dev Comp Immunol . 2015 Apr;49(2):217-24. (IF 3.192)

63. Zhang J, Song J, Wu D, Wang J, Dong W.
Hesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species, ATP and calcium.
Med Oncol . 2015 Apr;32(4):101. (IF 2.834)

64. Wang B, Li C, Huai R, Qu Z.
Overexpression of ANO1/TMEM16A, an arterial Ca2+-activated Cl- channel, contributes to spontaneous hypertension.
J Mol Cell Cardiol . 2015 May;82:22-32. (IF 4.133)

65. Chen J, Hu Z, Zhuan L, Xiao H, Zhang Y, Yang J.
Intracellular calcium concentration of corpus cavernosum smooth muscle cells is decreased by the overexpression of PnNOS gene in adipose tissue-derived stem cells.
Andrologia . 2015 Aug;47(6):711-9. (IF 1.951)

66. Hu XL, Guo LP, Song Q, Zhang Q, Chen Y, Wang J, Meng WH, Zhao QC.
Kukoamine B, an amide alkaloid, protects against NMDA-induced neurotoxicity and potential mechanisms in vitro.
Neurochem Int . 2015 Aug;87:66-76. (IF 3.881)

67. Li Z, Zhang Y, Peng D, Wang X, Peng Y, He X, Zhang X, Ma X, Huang L, Yan Y.
Polyamine regulates tolerance to water stress in leaves of white clover associated with antioxidant defense and dehydrin genes via involvement in calcium messenger system and hydrogen peroxide signaling.
Front Physiol . 2015 Oct 12;6:280. (IF 3.367)

68. Wang J, Ming H, Chen R, Ju JM, Peng WD, Zhang GX, Liu CF.
CIH-induced neurocognitive impairments are associated with hippocampal Ca(2+) overload, apoptosis, and dephosphorylation of ERK1/2 and CREB that are mediated by overactivation of NMDARs.
Brain Res . 2015 Nov 2;1625:64-72. (IF 2.733)

69. Tian X, Chang L, Ma G, Wang T, Lv M, Wang Z, Chen L, Wang Y, Gao X, Zhu Y.
Delineation of platelet activation pathway of Scutellarein revealed its intracellular target as Protein Kinase C.
Biol Pharm Bull . 2016;39(2):181-91. (IF 1.863)

70. Tang QF, Sun J, Yu H, Shi XJ, Lv R, Wei HC, Yin PH.
The Zuo Jin Wan Formula Induces Mitochondrial Apoptosis of Cisplatin-Resistant Gastric Cancer Cells viaCofilin-1.
EVID-BASED COMPL ALT . 2016;2016:8203789. (IF 1.813)

71. Luo D, Ni Q, Ji A, Gu W, Wu J, Jiang C.
Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and
Biomed Res Int . 2016;2016:2581061. (IF 2.276)

72. Zhao F, Fu L, Yang W, Dong Y, Yang J, Sun S, Hou Y.
Cardioprotective effects of baicalein on heart failure via modulation of Ca2+ handling proteins in vivo and in vitro.
Life Sci . 2016 Jan;145:213-23. (IF 3.647)

73. Zhao F, Fu L, Yang W, Dong Y, Yang J, Sun S, Hou Y.
Cardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitro.
Life Sci . 2016 Jan 15;145:213-23. (IF 3.647)

74. Wu M, Wu D, Wang C, Guo Z, Li B, Zuo Z.
Hexabromocyclododecane exposure induces cardiac hypertrophy and arrhythmia by inhibiting miR-1expression via up-regulation of the homeobox gene Nkx2.5.
J Hazard Mater . 2016 Jan 25;302:304-13. (IF 9.038)

75. Du C, Li Y, Guo Y, Han M, Zhang W, Qian H.
The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors.
BIOCHEM BIOPH RES CO . 2016 Jan 22;469(4):1146-52. (IF 2.985)

76. Tao K, Wang B, Feng D, Zhang W, Lu F, Lai J, Huang L, Nie T, Yang Q.
Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress.
Neurosci Bull . 2016 Feb;32(1):61-9. (IF 4.326)

77. Yang L, Sui W, Li Y, Qi X, Wang Y, Zhou Q, Gao H.
Substance P Inhibits Hyperosmotic Stress-Induced Apoptosis in Corneal Epithelial Cells through theMechanism of Akt Activation and Reactive Oxygen Species Scavenging via the Neurokinin-1 Receptor.
PLoS One . 2016 Feb 22;11(2):e0149865. (IF 2.74)

78. Wang MD, Wu H, Huang S, Zhang HL, Qin CJ, Zhao LH, Fu GB, Zhou X, Wang XM, Tang L, Wen W, Yang W, Tang SH, Cao D, Guo LN, Zeng M, Wu MC, Yan HX, Wang HY.
HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress.
ONCOTARGET . 2016 Feb 9;7(6):6711-26. (IF 5.168)

79. Chang R, Zhou R, Qi X, Wang J, Wu F, Yang W, Zhang W, Sun T, Li Y, Yu J.
Protective effects of aloin on oxygen and glucose deprivation-induced injury in PC12 cells.
Brain Res Bull . 2016 Mar;121:75-83. (IF 3.37)

80. Lv S, Xu QY, Sun EC, Zhang JK, Wu DL.
Dissection and integration of the autophagy signaling network initiated by bluetongue virus
SCI REP-UK . 2016 Mar 15;6:23130. (IF 3.998)

81. He C, Jiang S, Jin H, Chen S, Lin G, Yao H, Wang X, Mi P, Ji Z, Lin Y, Lin Z, Liu G.
Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediatedcancer-specific cytotoxicity.
Biomaterials . 2016 Mar;83:102-14. (IF 10.317)

82. Sun X, Shi X, Lu L, Jiang Y, Liu B.
Stimulus-dependent neuronal cell responses in SH-SY5Y neuroblastoma cells.
Mol Med Rep . 2016 Mar;13(3):2215-20. (IF 2.1)

83. He B, Yuan L, Dai W, Gao W, Zhang H, Wang X, Fang W, Zhang Q.
Dynamic bio-adhesion of polymer nanoparticles on MDCK epithelial cells and its impact on
Nanoscale . 2016 Mar 21;8(11):6129-45. (IF 6.895)

84. Zhao M, Li H, Liu X, Wei J, Ji J, Yang S, Hu Z, Wei S.
Response of Human Osteoblast to n-HA/PEEK–Quantitative Proteomic Study of Bio-effects of Nano-Hydroxyapatite Composite.
SCI REP-UK . 2016 Mar 9;6:22832. (IF 3.998)

85. Wu XT, Sun LW, Qi HY, Shi H, Fan YB.
The bio-response of osteocytes and its regulation on osteoblasts under vibration.
Cell Biol Int . 2016 Apr;40(4):397-406. (IF 2.571)

86. Jiang Q, Liu Y, Duan D, Gou M, Wang H, Wang J, Li Q, Xiao R.
Anti-angiogenic activities of CRBGP from buccal glands of lampreys (Lampetra japonica).
Biochimie . 2016 Apr;123:7-19. (IF 3.413)

87. Chen X, Sun FJ, Wei YJ, Wang LK, Zang ZL, Chen B, Li S, Liu SY, Yang H.
Increased Expression of Transient Receptor Potential Vanilloid 4 in Cortical Lesions of Patients with FocalCortical Dysplasia.
CNS Neurosci Ther . 2016 Apr;22(4):280-90. (IF 4.074)

88. Zhang C, Lu T, Wang GD, Ma C, Zhou YF.
Costunolide, an active sesquiterpene lactone, induced apoptosis via ROS-mediated
Biomed Pharmacother . 2016 May;80:253-9. (IF 4.545)

89. Zhou X, Wei Y, Qiu S, Xu Y, Zhang T, Zhang S.
Propofol Decreases Endoplasmic Reticulum Stress-Mediated Apoptosis in Retinal Pigment Epithelial Cells.
PLoS One . 2016 Jun 16;11(6):e0157590. (IF 2.74)

90. Li M, He HP, Gong HQ, Zhang J, Ma WJ, Zhou H, Cao DS, Wang N, Zhang TC.
NFATc4 and myocardin synergistically up-regulate the expression of LTCC α1C in ET-1-inducedcardiomyocyte hypertrophy.
Life Sci . 2016 Jun 15;155:11-20. (IF 3.647)

91. Song X, Zhang Y, Wang H, Wen H, Zhao C, Lan Y, Pan L, Zhang C, Cheng M.
Stereoselectivity of tradinterol’s inhibition on proliferation of airway smooth muscle cells induced by acetylcholine through suppressing Ca(2+) signalling.
J Physiol Pharmacol . 2016 Jun;67(3):363-75. (IF 2.644)

92. Liu Y, Wang XC, Hu D, Huang SR, Li QS, Li Z, Qu Y.
Heat shock protein 70 protects PC12 cells against ischemia-hypoxia/reoxygenation by maintainingintracellular Ca(2+) homeostasis.
Neural Regen Res . 2016 Jul;11(7):1134-40. (IF 3.171)

93. Meng X, Li X, Wang X, Gao J, Yang H, Chen H.
Potential allergenicity response to structural modification of irradiated bovine α-lactalbumin.
Food Funct . 2016 Jul 13;7(7):3102-10. (IF 4.171)

94. Liu M, Feng LX, Sun P, Liu W, Wu WY, Jiang BH, Yang M, Hu LH, Guo DA, Liu X.
A Novel Bufalin Derivative Exhibited Stronger Apoptosis-Inducing Effect than Bufalin in A549 Lung CancerCells and Lower Acute Toxicity in Mice.
PLoS One . 2016 Jul 26;11(7):e0159789. (IF 2.74)

95. Gong H, Liu L, Ni CX, Zhang Y, Su WJ, Lian YJ, Peng W, Zhang JP, Jiang CL.
Dexamethasone rapidly inhibits glucose uptake via non-genomic mechanisms in contracting myotubes.
Arch Biochem Biophys . 2016 Aug 1;603:102-9. (IF 3.391)

96. Jiang Y, Gou H, Zhu J, Tian S, Yu L.
Lidocaine inhibits the invasion and migration of TRPV6-expressing cancer cells by TRPV6 downregulation.
Oncol Lett . 2016 Aug;12(2):1164-1170. (IF 2.311)

97. Wang Y, Wang D, Zhang L, Ye F, Li M, Wen K.
Role of JAK-STAT pathway in reducing cardiomyocytes hypoxia/reoxygenation injury induced by S1Ppostconditioning.
Eur J Pharmacol . 2016 Aug 5;784:129-36. (IF 3.263)

98. Bi C, Jiang Y, Fu T, Hao Y, Zhu X, Lu Y.
Naringin inhibits lipopolysaccharide-induced damage in human umbilical vein endothelial cells viaattenuation of inflammation, apoptosis and MAPK pathways.
Cytotechnology . 2016 Aug;68(4):1473-87. (IF 1.777)

99. Chen C, Huang L, Zhang G, Li Y, Li L, Bai X, Liu W, Wang H, Li J.
STK33 potentiates the malignancy of hypopharyngeal squamous carcinoma: Possible relation to calcium.
Cancer Biol Ther . 2016 Sep;17(9):976-84. (IF 3.659)

100. Guo L, Lv G, Qiu L, Yang H, Zhang L, Yu H, Zou M, Lin J.
Insights into anticancer activity and mechanism of action of a ruthenium(II) complex in human esophagealsquamous carcinoma EC109 cells.
Eur J Pharmacol . 2016 Sep 5;786:60-71. (IF 3.263)

101. Cai Q, Ma T, Li C, Tian Y, Li H.
Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury throughERK1/2 Signaling Pathway.
Int J Biol Sci . 2016 Oct 26;12(12):1415-1426. (IF 4.858)

102. Cui X, Liang T, Liu C, Yuan Y, Qian J.
Correlation of particle properties with cytotoxicity and cellular uptake of hydroxyapatite nanoparticles inhuman gastric cancer cells.
MAT SCI ENG C-MATER . 2016 Oct 1;67:453-60. (IF 5.88)

103. Sun T, Guo Z, Liu CJ, Li MR, Li TP, Wang X, Yuan DJ.
Preservation of CGRP in myocardium attenuates development of cardiac dysfunction in diabetic rats.
Int J Cardiol . 2016 Oct 1;220:226-34. (IF 3.229)

104. Liu Z, Gan L, Wu T, Feng F, Luo D, Gu H, Liu S, Sun C.
Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 inmouse adipose.
Cell Death Dis . 2016 Nov 24;7(11):e2487. (IF 6.304)

105. Liu Z, Zhou Z, Wang L, Qiu L, Zhang H, Wang H, Song L.
CgA1AR-1 acts as an alpha-1 adrenergic receptor in oyster Crassostrea gigas mediating both cellular andhumoral immune response.
FISH SHELLFISH IMMUN . 2016 Nov;58:50-58. (IF 3.298)

106. Tu LY, Bai HH, Cai JY, Deng SP.
The mechanism of kaempferol induced apoptosis and inhibited proliferation in human cervical cancer SiHacell: From macro to nano.
Scanning . 2016 Nov;38(6):644-653. (IF 1.33)

107. Pi J, Huang L, Yang F, Jiang J, Jin H, Liu J, Su X, Wu A, Cai H, Yang P, Cai J.
Atomic force microscopy study of ionomycin-induced degranulation in RBL-2H3 cells.
Scanning . 2016 Nov;38(6):525-534. (IF 1.33)

108. Liu Z, Gu H, Gan L, Xu Y, Feng F, Saeed M, Sun C.
Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brownadipose tissue.
ONCOTARGET . 2016 Dec 20.doi: 10.18632/oncotarget.14035. [Epub ahead of print] (IF 5.168)

109. Zhang J, Wang Y, Sun KM, Fang K, Tang X.
A study of oxidative stress induced by two polybrominated diphenyl ethers inhe rotifer Brachionusplicatilis.
Mar Pollut Bull . 2016 Dec 15;113(1-2):408-413. (IF 4.049)

110. Hu L, Sun J, Li H, Wang L, Wei Y, Wang Y, Zhu Y, Huo H, Tan Y.
Differential mechanistic investigation of protective effects from imperatorin and sec-O-glucosylhamaudolagainst arsenic trioxide-induced cytotoxicity in vitro.
Toxicol In Vitro . 2016 Dec;37:97-105. (IF 2.959)

111. Liu Z, Zhou Z, Wang L, Dong W, Qiu L, Song L.
The cholinergic immune regulation mediated by a novel muscarinic acetylcholine receptor through TNFpathway in oyster Crassostrea gigas.
Dev Comp Immunol . 2016 Dec;65:139-48. (IF 3.192)

112. Liu Y, Zhi D, Li M, Liu D, Wang X, Wu Z, Zhang Z, Fei D, Li Y, Zhu H, Xie Q, Yang H, Li H.
Shengmai Formula suppressed over-activated Ras/MAPK pathway in C. elegans by opening mitochondrialpermeability transition pore via regulating cyclophilin D.
SCI REP-UK . 2016 Dec 16;6:38934. (IF 3.998)

113. Jiang F, Zhou JY, Wu J, Tian F, Zhu XX, Zhu CL, Yang BL, Chen YG.
Yangyin Runchang Decoction Improves Intestinal Motility in Mice with Atropine/Diphenoxylate-Induced Slow-Transit Constipation.
EVID-BASED COMPL ALT . 2017;2017:4249016. (IF 1.813)

114. Wang X, Guo Q, Tao L, Zhao L, Chen Y, An T, Chen Z, Fu R.
E platinum, a newly synthesized platinum compound, induces apoptosis through ROS-triggered ER stressin gastric carcinoma cells.
MOL CARCINOGEN . 2017 Jan;56(1):218-231. (IF 3.825)

115. Wu XT, Sun LW, Yang X, Ding D, Han D, Fan YB.
The potential role of spectrin network in the mechanotransduction of MLO-Y4 osteocytes.
SCI REP-UK . 2017 Jan 23;7:40940. (IF 3.998)

116. Chen Y, Huang L, Zhang H, Diao X, Zhao S, Zhou W.
Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention ofMitochondrial Dysfunction After Subarachnoid Hemorrhage.
Mol Neurobiol . 2017 Jan;54(1):392-405. (IF 4.5)

117. Dai J, Wu S, Kong Y, Chi Z, Si L, Sheng X, Cui C, Fang J, Zhang J, Guo J.
Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects of the mTOR Inhibitor Everolimusagainst Melanoma.
SCI REP-UK . 2017 Jan 5;7:39597. (IF 3.998)

118. Chen Y, Huang L, Zhang H, Diao X, Zhao S, Zhou W.
Reduction in Autophagy by(-)-Epigallocatechin-3-Gallate (EGCG):a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage.
Mol Neurobiol . 2017 Jan;54(1):392-405. (IF 4.5)

119. Dai J, Wu S, Kong Y, Chi Z, Si L, Sheng X, Cui C, Fang J, Zhang J, Guo J.
Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects ofthe mTOR InhibitorEverolimus against Melanoma.
SCI REP-UK . 2017 Jan 5;7:39597. doi: 10.1038/srep39597. (IF 3.998)

120. Wu XT, Sun LW, Yang X, Ding D, Han D, Fan YB.
The potential role of spectrin network inthe mechanotransduction of MLO-Y4 osteocytes.
SCI REP-UK . 2017 Jan 23;7:40940. (IF 3.998)

121. Wang X, Guo Q, Tao L, Zhao L, Chen Y, An T, Chen Z, Fu R.
E platinum,a newly synthesized platinum compound, induces apoptosis through ROS-triggeredER stress in gastric carcinoma cells.
MOL CARCINOGEN . 2017 Jan;56(1):218-231. (IF 3.825)

122. Qiu Y, Yu Q, Shi K, Zhang M, Zhou X, Yang Y, Liu Y, Tang J, Wang X, He Q.
Cell-penetrating peptides induce apoptosis and necrosis through specific mechanism and causeimpairment of Na+-K+-ATPase and mitochondria.
Amino Acids . 2017 Jan;49(1):75-88. (IF 3.063)

123. Liu Q, Ji X, Ge Z, Diao H, Chang X, Wang L, Wu Q.
Role of connexin 43 in cadmium-induced proliferation of human prostate epithelial cells.
J Appl Toxicol . 2017 Feb 8. doi: 10.1002/jat.3441. (IF 2.997)

124. Liu Z, Gu H, Gan L, Xu Y, Feng F, Saeed M, Sun C.
Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in micebrown adipose tissue.
ONCOTARGET . 2017 Feb 7;8(6):9267-9279. (IF 5.168)

125. Hu Y, Zhang C, Li S, Jiao Y, Qi T, Wei G, Han G.
Effects of Photodynamic Therapy Using Yellow LED-light with Concomitant Hypocrellin B on Apoptotic Signaling in Keloid Fibroblasts.
Int J Biol Sci . 2017 Feb 25;13(3):319-326. (IF 4.858)

126. Ye W, Zhu S, Liao C, Xiao J, Wu Q, Lin Z, Chen J.
Advanced oxidation protein products induce apoptosis of human chondrocyte through reactiveoxygen species-mediated mitochondrial dysfunction and endoplasmic reticulum stress pathways.
FUND CLIN PHARMACOL . 2017 Feb;31(1):64-74. (IF 2.754)

127. Guo H, Guan H, Yang W, Liu H, Hou H, Chen X, Liu Z, Zang C, Liu Y, Liu J.
Pro-apoptotic and anti-proliferative effects of corn silk extract on human colon cancer cell lines.
Oncol Lett . 2017 Feb;13(2):973-978. (IF 2.311)

128. Jiang Q, Li Q, Han J, Gou M, Zheng Y, Li B, Xiao R, Wang J.
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration andinvasion of human HeyA8 cells via FAK pathway.
Int J Biol Macromol . 2017 Mar;96:652-668. (IF 5.162)

129. Wang C, Qi S, Liu C, Yang A, Fu W, Quan C, Duan P, Yu T, Yang K.
Mitochondrial Dysfunction and Ca2+ Overload in Injured Sertoli Cells Exposed to Bisphenol A.
Environ Toxicol . 2017 Mar;32(3):823-831. (IF 3.118)

130. Jiang Q, Li Q, Han J, Gou M, Zheng Y, Li B, Xiao R, Wang J.
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway.
Int J Biol Macromol . 2017 Mar;96:652-668. (IF 5.162)

131. Wang XP, Yu X, Yan XJ, Lei F, Chai YS, Jiang JF, Yuan ZY, Xing DM, Du LJ.
TRPM8 inthe negative regulation ofTNFα expression during cold stress.
SCI REP-UK . 2017 Mar 23;7:45155. (IF 3.998)

132. Wang P, Gao YM, Sun X, Guo N, Li J, Wang W, Yao LP, Fu YJ.
Hepatoprotective effect of 2′-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway.
Food Chem Toxicol . 2017 Apr;102:129-142. (IF 4.679)

133. Xiang W, Liao W, Yi Z, He X, Ding Y.
25-Hydroxyvitamin D-1-α-hydroxylasein apoliporotein E knockout mice:The role of protectingvascular smooth muscle cell from calcification.
Biomed Pharmacother . 2017 Apr;88:971-977. (IF 4.545)

134. Zhu J, Li ZG, Wang BQ, Tong XL, Peng QH.
[Effect of Qibai Pingfei capsule medicated serum on protein expressions of KATP channel in pulmonary arterial smooth muscle cells via nitric oxide].
《中国中药杂志》 . 2017 Apr;42(7):1376-1381.

135. Lu Y, Gu Y, Ding X, Wang J, Chen J, Miao C.
Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved inthe protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis.
PLoS One . 2017 May 23;12(5):e0178098. (IF 2.74)

136. Gu C, Yao J, Sun P.
Dynamin 3 suppresses growth and induces apoptosis of hepatocellular carcinoma cells by activating inducible nitric oxide synthase production.
Oncol Lett . 2017 Jun;13(6):4776-4784. (IF 2.311)

137. Li C, Li L, Lin B, Fang Y, Yang H, Liu H, Xi Z.
Tris (1,3-dichloro-2-propyl) phosphate induces toxicity by stimulating CaMK2 in PC12 cells.
Environ Toxicol . 2017 Jun;32(6):1784-1791. (IF 3.118)

138. Huang YF, Zhu DJ, Chen XW, Chen QK, Luo ZT, Liu CC, Wang GX, Zhang WJ, Liao NZ.
Curcumin enhances the effects of irinotecan on colorectal cancer cells throughthe generation of reactive oxygen species and activation ofthe endoplasmic reticulum stress pathway.
ONCOTARGET . 2017 Jun 20;8(25):40264-40275. (IF 5.168)

139. Yang K, Jiang X, Su Q, Wang J, Li C, Xia Y, Cheng S, Qin Q, Cao X, Chen C, Tu B.
Disruption of glutamate neurotransmitter transmission is modulated by SNAP-25 in benzo[a]pyrene-induced neurotoxic effects.
Toxicology . 2017 Jun 1;384:11-22. (IF 4.099)

140. Zhao T, Chang L, Zhang B, Lu M, Wang X, Orgah JO, Wang Y, Tian X, Yang J, Fan G, Zhang B, Zhu Y.
Specific Combination of Salvianolic Acids As Core Active Ingredients of Danhong Injection for Treatment of Arterial Thrombosis andIts Derived Dry Gangrene.
Front Pharmacol . 2017 Jun 13;8:361. (IF 4.225)

141. Xu Z, Lu Y, Wang J, Ding X, Chen J, Miao C.
The protective effect of propofol against TNF-α-induced apoptosis was mediated via inhibitingiNOS/NO production and maintaining intracellular Ca2+ homeostasis in mouse hippocampal HT22 cells.
Biomed Pharmacother . 2017 Jul;91:664-672. (IF 4.545)

142. Zhu G, Tao L, Wang R, Xue Y, Wang X, Yang S, Sun X, Gao G, Mao Z, Yang Q.
Endoplasmic reticulum stress mediates distinct impacts of sevoflurane on different subfields of immature hippocampus.
J Neurochem . 2017 Jul;142(2):272-285. (IF 4.066)

143. Zhao K, Li G, Yao Y, Zhou Y, Li Z, Guo Q, Lu N.
Activation of phospholipase C-γ1and translocation of phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase contribute to GL-V9-induced apoptosis in human gastric cancer cells.
Exp Cell Res . 2017 Jul 1;356(1):8-19. (IF 3.383)

144. Xiang QD, Yu Q, Wang H, Zhao MM, Liu SY, Nie SP, Xie MY.
Immunomodulatory Activity of Ganoderma atrum Polysaccharide on Purified T Lymphocytes through Ca2+/CaNand Mitogen-Activated Protein Kinase Pathway Based on RNA Sequencing.
J AGR FOOD CHEM . 2017 Jul 5;65(26):5306-5315. (IF 4.192)

145. Liu S, Fei W, Shi Q, Li Q, Kuang Y, Wang C, He C, Hu X.
CHAC2, downregulated in gastric and colorectal cancers, acted asa tumor suppressor inducingapoptosis and autophagy through unfolded protein response.
Cell Death Dis . 2017 Aug 24;8(8):e3009. (IF 6.304)

146. Qiu LY, Duan GL, Yan YF, Li YY, Wang H, Xiao L, Liao ZP, Chen HP.
Sasanquasaponin induces increase of Cl /HCO3 exchange of anion exchanger 3 and promotesintracellular Cl efflux in hypoxia/reoxygenation cardiomyocytes.
Mol Med Rep . 2017 Sep;16(3):2953-2961. (IF 2.1)

147. Zhang X, Xu L, Tian H, Wang C, Wang W, Ru S.
Monocrotophos,an organophosphorus insecticide, disrupts the expression of HpNetrin andits receptor neogenin during early development inthe sea urchin (Hemicentrotus pulcherrimus).
Neurotoxicology . 2017 Sep;62:130-137. (IF 3.105)

148. Qiu L, Ma Y, Luo Y, Cao Z, Lu H.
Protective effects of isorhamnetin on N2a cell against endoplasmic reticulum stress-inducedinjury is mediated by PKCε.
Biomed Pharmacother . 2017 Sep;93:830-836. (IF 4.545)

149. Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Cell Tissue Res . 2017 Sep;369(3):455-465. (IF 4.044)

150. Zhang Y, Wang L, Feng H, Hu G, Wang L, Liu J, Gao X, Shang J, Zhu T, Tang S, Jia G.
Effects of 1,4-naphthoquinone aged carbon black particles onthe cell membrane of humanbronchial epithelium.
ENVIRON TOXICOL CHEM . 2017 Sep;54:21-27. (IF 3.152)

151. Chen LD, Liu ZH, Zhang LF, Yao JN, Wang CF.
Sanggenon C induces apoptosis of colon cancer cells via inhibition ofNO production, iNOSexpression and ROS activation ofthe mitochondrial pathway.
Oncol Rep . 2017 Oct;38(4):2123-2131. (IF 3.417)

152. Xu W, Guan R, Shi F, Du A, Hu S.
Structural analysis and immunomodulatory effect of polysaccharide from Atractylodismacrocephalae Koidz. on bovine lymphocytes.
CARBOHYD POLYM . 2017 Oct 15;174:1213-1223. (IF 7.182)

153. Xiang Y, Jing Z, Haixia W, Ruitao Y, Huaixiu W, Zenggen L, Lijuan M, Yiping W, Yanduo T.
Antiproliferative Activity of Phenylpropanoids Isolated from Lagotis brevituba Maxim.
Phytother Res . 2017 Oct;31(10):1509-1520. (IF 4.087)

154. Lin H, Ma X, Wang BC, Zhao L, Liu JX, Pu FF, Hu YQ, Hu HZ, Shao ZW.
Edaravone ameliorates compression-induced damage in rat nucleus pulposus cells.
Life Sci . 2017 Nov 15;189:76-83. (IF 3.647)

155. Li N, Xu P, Jing WX, Hwang JS, Wang L.
Toxic effects of Pb2+ entering sperm through Ca2+ channels inthe freshwater crab Sinopotamonhenanense.
Aquat Toxicol . 2017 Nov;192:24-29. (IF 4.344)

156. Li Y, Chen Y, Huang H, Shi M, Yang W, Kuang J, Yan J.
Autophagy mediated by endoplasmic reticulum stress enhances the caffeine-induced apoptosis of hepatic stellate cells.
Int J Mol Med . 2017 Nov;40(5):1405-1414. (IF 3.098)

157. Sun N, Jin Z, Li D, Yin H, Lin S.
An Exploration ofthe Calcium-Binding Mode of Egg White Peptide, Asp-His-Thr-Lys-Glu,andIn Vitro Calcium Absorption Studies of Peptide-Calcium Complex.
J AGR FOOD CHEM . 2017 Nov 8;65(44):9782-9789. (IF 4.192)

158. Xu N, An J.
Formononetin ameliorates mast cell-mediated allergic inflammation via inhibition of histaminerelease and production of pro-inflammatory cytokines.
Exp Ther Med. 2017 Dec;14(6):6201-6206. (IF 1.785)

159. Jianfei L, Min W, Chunlai M, Bicui C, Jiming Z, Bin W.
The Ca2+/CaMKK2 axis mediates the telbivudine induced upregulation of creatine kinase: Implications for mechanism of antiviral nucleoside analogs’ side effect.
Biochem Pharmacol . 2017 Dec 15;146:224-232. (IF 4.96)

160. Wu DP, Lin TY, Bai LR, Huang JL, Zhou Y, Zhou N, Zhong SL, Gao S, Yin XX.
Enhanced phototoxicity of photodynamic treatment by Cx26-composed GJIC via ROS-,calcium-and lipid peroxide-mediated pathways.
J Biophotonics . 2017 Dec;10(12):1586-1596. (IF 3.032)

161. Yao H, Yuan Z, Wei G, Chen C, Duan J, Li Y, Wang Y, Zhang C, Liu Y.
Thevetiaflavone from Wikstroemia indica ameliorates PC12 cells injury induced by OGD/R via improving ROS mediated mitochondrial dysfunction.
Mol Med Rep . 2017 Dec;16(6):9197-9202. (IF 2.1)

162. Chen X,Wu Q,Sun P,Zhao Y,Zhu M,Miao C
Propofol Disrupts Aerobic Glycolysis in Colorectal Cancer Cells via Inactivation of the NMDAR-CAMKII-ERK Pathway.
CELL PHYSIOL BIOCHEM. 2018;46(2):492-504. (IF 5.5)

163. Yang H,Li X,Liu Y,Li X,Li X,Wu M,Lv X,Chunhua C,Ding X,Zhang Y
Crocin Improves the Endothelial Function Regulated by Kca3.1 Through ERK and Akt Signaling Pathways.
CELL PHYSIOL BIOCHEM. 2018;46(2):765-780. (IF 5.5)

164. Du Y,Fu M,Wang YT,Dong Z
Neuroprotective Effects of Ginsenoside Rf on Amyloid-β-Induced Neurotoxicity in vitro and in vivo.
J Alzheimers Dis. 2018;64(1):309-322. (IF 3.909)

165. Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T.
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation,and InducesApoptosis in A549 Lung Adenocarcinoma Cells.
Oxid Med Cell Longev . 2018 Jan 11;2018:3853409. (IF 5.076)

166. Yan D, Zhu D, Zhao X, Su J.
SHP-2 restricts apoptosis induced by chemotherapeutic agents via Parkin-dependent autophagy in cervical cancer.
Cancer Cell Int . 2018 Jan 15;18:8. (IF 4.175)

167. Maryam A,Mehmood T,Yan Q,Li Y,Khan M,Ma T
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Oxid Med Cell Longev . 2018 Jan 11;2018:3853409. (IF 5.076)

168. Dong X, Gao X, Dai Y, Ran N, Yin H.
Serum exosomes can restore cellular function in vitro and be used for diagnosis in dysferlinopathy.
Theranostics . 2018 Feb 2;8(5):1243-1255. (IF 8.579)

169. Li Z, Tang Y, Zhu S, Li D, Han X, Gu G, Xing N, Ren J, Guo Z, Jiao W, Yan L, Xu Z, Zhang W.
Ethanol extract of Patrinia scabiosaefolia induces the death of human renal cell carcinoma 786-Ocells via SIRT-1 and mTOR signaling-mediated metabolic disruptions.
Oncol Rep . 2018 Feb;39(2):764-772. (IF 3.417)

170. Shen XY, Luo T, Li S, Ting OY, He F, Xu J, Wang HQ.
Quercetin inhibits okadaic acid-induced tau protein hyperphosphorylation through the Ca2+ calpain p25 CDK5 pathway in HT22 cells.
Int J Mol Med . 2018 Feb;41(2):1138-46. (IF 3.098)

171. Shen XY,Luo T,Li S,Ting OY,He F,Xu J,Wang HQ
Quercetin inhibits okadaic acid-induced tau protein hyperphosphorylation through the Ca2+‑calpain‑p25‑CDK5 pathway in HT22 cells.
Int J Mol Med. 2018 Feb;41(2):1138-1146. (IF 3.098)

172. Liu L, Chang X, Zhang Y, Wu C, Li R, Tang L, Zhou Z.
Fluorochloridone induces primary cultured Sertoli cells apoptosis: Involvement of ROS and intracellular calcium ions-mediated ERK1/2 activation.
Toxicol In Vitro . 2018 Mar;47:228-237. (IF 2.959)

173. Huang RZ, Huang XC, Zhang B, Jia HY, Liao ZX, Wang HS.
16-O-caffeoyl-16-hydroxylhexadecanoic acid, a medicinal plant-derived phenylpropanoid, inducesapoptosis in human hepatocarcinoma cells through ROS-dependent endoplasmic reticulum stress.
Phytomedicine . 2018 Mar 1;41:33-44. (IF 4.268)

174. Zhao P, Chang RY, Liu N, Wang J, Zhou R, Qi X, Liu Y, Ma L, Niu Y, Sun T, Li YX, He YP, Yu JQ.
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat HippocampalNeurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Cell Mol Neurobiol . 2018 Mar;38(2):529-540. (IF 3.606)

175. Guo C, Ma R, Liu X, Chen T, Li Y, Yu Y, Duan J, Zhou X, Li Y, Sun Z.
Silica nanoparticles promote oxLDL-induced macrophage lipid accumulation and apoptosis viaendoplasmic reticulum stress signaling.
Sci Total Environ . 2018 Mar 10;631-632:570-579. (IF 6.551)

176. Ma K, Shi W, Xu M, Liu J, Zhang F.
Genome-Wide Identification and Characterization of Long Non-Coding RNA in Wheat Roots in Response to Ca2+ Channel Blocker.
Front Plant Sci . 2018 Mar 6;9:244. (IF 4.402)

177. Hu M, Zhao W, Li H, Gu J, Yan Q, Zhou X, Pan Z, Cui G, Jiao X.
Immunization with recombinant Salmonella expressing SspH2-EscI protects mice against wildtype Salmonella infection.
BMC Vet Res . 2018 Mar 9;14(1):79. (IF 1.835)

178. Wang Z,Cui R,Wang K
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Exp Ther Med . 2018 Mar;15(3):2818-2823. (IF 1.785)

179. Liu Y,Wang H,Yang M,Liu N,Zhao Y,Qi X,Niu Y,Sun T,Li Y,Yu J
Cistanche deserticola polysaccharides protects PC12 cells against OGD/RP-induced injury.
Biomed Pharmacother . 2018 Mar;99:671-680. (IF 4.545)

180. Zhao P,Chang RY,Liu N,Wang J,Zhou R,Qi X,Liu Y,Ma L,Niu Y,Sun T,Li YX,He YP,Yu JQ
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Cell Mol Neurobiol . 2018 Mar;38(2):529-540. (IF 3.606)

181. Hu M,Zhao W,Li H,Gu J,Yan Q,Zhou X,Pan Z,Cui G,Jiao X
Immunization with recombinant Salmonella expressing SspH2-EscI protects mice against wild type Salmonella infection.
BMC Vet Res. 2018 Mar 9;14(1):79. (IF 1.835)

182. Yang Y, Chen Q, Jia S, He L, Wang A, Li D, Li Y, Li X.
Involvement of TRPV1 inthe expression and release of calcitonin gene-related peptide induced by rutaecarpine.
Mol Med Rep . 2018 Apr;17(4):5168-5174. (IF 2.1)

183. Yu H,Yang X,Tang X,Tang R
Effects of spontaneous recurrent seizures on cognitive function via modulation of SNAREs expression.
Int J Neurosci. 2018 Apr;128(4):376-383. (IF 2.107)

184. Guo C, Wang J, Jing L, Ma R, Liu X, Gao L, Cao L, Duan J, Zhou X, Li Y, Sun Z.
Mitochondrial dysfunction, perturbations of mitochondrial dynamics and biogenesis involved in endothelial injury induced by silica nanoparticles.
Environ Pollut . 2018 May;236:926-936. (IF 6.792)

185. Jia Y, Yang B, Dong W, Liu Z, Lv Z, Jia Z, Qiu L, Wang L, Song L.
A serotonin receptor (Cg5-HTR-1) mediating immune response in oyster Crassostrea gigas.
Dev Comp Immunol . 2018 May;82:83-93. (IF 3.192)

186. Jia Y,Miao Y,Yue M,Shu M,Wei Z,Dai Y
Tetrandrine attenuates the bone erosion in collagen-induced arthritis rats by inhibiting osteoclastogenesis via spleen tyrosine kinase.
FASEB J. 2018 Jun;32(6):3398-3410. (IF 4.966)

187. Liao C,Xu D,Liu X,Fang Y,Yi J,Li X,Guo B
Iridium (III) complex-loaded liposomes as a drug delivery system for lung cancer through mitochondrial dysfunction.
INT J NANOMED. 2018 Jul 30;13:4417-4431. (IF 5.115)

188. Tao X,Li N,Liu F,Hu Y,Liu J,Zhang YM
In vitro examination of microglia-neuron crosstalk with BV2 cells, and primary cultures of glia and hypothalamic neurons.
Heliyon . 2018 Aug 22;4(8):e00730.

189. Yin H,Zhao L,Wang Y,Li S,Huo H,Chen H
Duck enteritis virus activates CaMKKβ-AMPK to trigger autophagy in duck embryo fibroblast cells via increased cytosolic calcium.
Virol J . 2018 Aug 6;15(1):120. (IF 2.579)

190. Zhu SY,Zhuang JS,Wu Q,Liu ZY,Liao CR,Luo SG,Chen JT,Zhong ZM
Advanced oxidation protein products induce pre-osteoblast apoptosis through a nicotinamide adenine dinucleotide phosphate oxidase-dependent, mitogen-activated protein kinases-mediated intrinsic apopto
Aging Cell. 2018 Aug;17(4):e12764. (IF 7.238)

191. Guo C,Ma R,Liu X,Chen T,Li Y,Yu Y,Duan J,Zhou X,Li Y,Sun Z
Silica nanoparticles promote oxLDL-induced macrophage lipid accumulation and apoptosis via endoplasmic reticulum stress signaling.
Sci Total Environ. 2018 Aug 1;631-632:570-579. (IF 6.551)

192. Guo X,Zheng M,Pan R,Zang B,Jin M
Hydroxysafflor Yellow A Suppresses Platelet Activating Factor-Induced Activation of Human Small Airway Epithelial Cells.
Front Pharmacol. 2018 Aug 3;9:859. (IF 4.225)

193. Qiao Y,Zheng H,Li L,Zhang J,Li Y,Li S,Zhu R,Zhou J,Zhao S,Jiang Y,Lou H
Terpenoids with vasorelaxant effects from the Chinese liverwort Scapania carinthiaca.
BIOORG MED CHEM LETT. 2018 Aug 7;26(14):4320-4328. (IF 2.572)

194. Cheng X,Feng H,Wu H,Jin Z,Shen X,Kuang J,Huo Z,Chen X,Gao H,Ye F,Ji X,Jing X,Zhang Y,Zhang T,Qiu W,Zhao R
Targeting autophagy enhances apatinib-induced apoptosis via endoplasmic reticulum stress for human colorectal cancer.
Cancer Lett . 2018 Sep 1;431:105-114. (IF 7.36)

195. Cui P,Lin S,Jin Z,Zhu B,Song L,Sun N
In vitro digestion profile and calcium absorption studies of a sea cucumber ovum derived heptapeptide-calcium complex.
Food Funct. 2018 Sep 19;9(9):4582-4592. (IF 4.171)

196. Li J,Ma L,Liao X,Liu D,Lu X,Chen S,Ye X,Ding T
Ultrasound-Induced Escherichia coli O157:H7 Cell Death Exhibits Physical Disruption and Biochemical Apoptosis.
Front Microbiol . 2018 Oct 16;9:2486. (IF 4.235)

197. Ma LQ,Yu Y,Chen H,Li M,Ihsan A,Tong HY,Huang XJ,Gao Y
Sweroside Alleviated Aconitine-Induced Cardiac Toxicity in H9c2 Cardiomyoblast Cell Line.
Front Pharmacol . 2018 Oct 25;9:1138. (IF 4.225)

198. Yuan XL,Zhao YP,Huang J,Liu JC,Mao WQ,Yin J,Peng BW,Liu WH,Han S,He XH
A Kv1.3 channel-specific blocker alleviates neurological impairment through inhibiting T-cell activation in experimental autoimmune encephalomyelitis.
CNS Neurosci Ther. 2018 Oct;24(10):967-977. (IF 4.074)

199. Zhang C,Xie L,Guan F,Cui Y
3H-1,2-dithiole-3-thione protects PC12 cells against amyloid beta 1-42 (Aβ1-42) induced apoptosis via activation of the ERK1/2 pathway.
Life Sci . 2018 Nov 15;213:74-81. (IF 3.647)

200. Tang R,Li ZP,Li MX,Li DW,Ye HB,Su KM,Lin H,Zhang WT
Pro-inflammatory role of transient receptor potential canonical channel 6 in the pathogenesis of chronic rhinosinusitis with nasal polyps.
INT FORUM ALLERGY RH. 2018 Nov;8(11):1334-1341. (IF 2.611)

201. Ding X,Ju X,Lu Y,Chen W,Wang J,Miao C,Chen J
Angiotensin II-mediated suppression of synaptic proteins in mouse hippocampal neuronal HT22 cell was inhibited by propofol: role of calcium signaling pathway.
J Anesth. 2018 Dec;32(6):856-865. (IF 1.628)

202. Song X,Liu Y,Dong L,Wang Y
Stromal-Interacting Molecule 1 (Stim1)/Orai1 Modulates Endothelial Permeability in Ventilator-Induced Lung Injury.
MED SCI MONITOR. 2018 Dec 27;24:9413-9423. (IF 1.918)

203. Cheng Q,Fang L,Feng D,Tang S,Yue S,Huang Y,Han J,Lan J,Liu W,Gao L,Luo Z
Memantine ameliorates pulmonary inflammation in a mice model of COPD induced by cigarette smoke combined with LPS.
Biomed Pharmacother. 2019 Jan;109:2005-2013. (IF 4.545)

204. Hu Q,Niu Q,Song H,Wei S,Wang S,Yao L,Li YP
Polysaccharides from Portulaca oleracea L. regulated insulin secretion in INS-1 cells through voltage-gated Na+ channel.
Biomed Pharmacother. 2019 Jan;109:876-885. (IF 4.545)

205. Tan Q,Zhang M,Geng L,Xia Z,Li C,Usman M,Du Y,Wei L,Bi H
Hormesis of methylmercury-human serum albumin conjugate on N9 microglia via ERK/MAPKs and STAT3 signaling pathways.
TOXICOL APPL PHARM . 2019 Jan 1;362:59-66. (IF 3.616)

206. Zhang X,Hong S,Qi S,Liu W,Zhang X,Shi Z,Chen W,Zhao M,Yin X
NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs.
MEDIAT INFLAMM. 2019 Feb 13;2019:6847087. (IF 3.758)

207. Liu SM,Xiao ZF,Li X,Zhao YN,Wu XM,Han J,Chen B,Li JY,Fan CX,Xu B,Xue XY,Xue WW,Yang Y,Dai JW
Vascular endothelial growth factor activates neural stem cells through epidermal growth factor receptor signal after spinal cord injury.
CNS Neurosci Ther. 2019 Mar;25(3):375-385. (IF 4.074)

208. Sun Z,Li Y,Zhou H,Cai M,Liu J,Gao S,Yang J,Tong L,Wang J,Zhou S,Hu Z,Wang Y,Wang K,Zhang L,Wang H,Zhang L,Shi F,Cao X,Zhang S,Ji Y,Zhao J
Simulated microgravity reduces intracellular-free calcium concentration by inhibiting calcium channels in primary mouse osteoblasts.
J Cell Biochem. 2019 Mar;120(3):4009-4020. (IF 4.237)

209. Wu DP,Ding CH,Bai LR,Zhou Y,Yang SM,Zhang F,Huang JL
Decreased phototoxicity of photodynamic therapy by Cx32/Cx26-composed GJIC: A “Good Samaritan” effect.
Lasers Surg Med. 2019 Mar;51(3):301-308.

210. Zhang M,Qiu S
Activation of GPR120 promotes the metastasis of breast cancer through the PI3K/Akt/NF-κB signaling pathway.
ANTI-CANCER DRUG. 2019 Mar;30(3):260-270. (IF 2.26)

211. Yang C,Li B,Wang G,Xing Y
The attenuation of myocardial hypertrophy by atorvastatin via the intracellular calcium signal and the p38 MAPK pathway.
INT J CLIN EXP PATHO. 2019 Mar 1;12(3):798-807. eCollection 2019. (IF 0.252)

212. Wang Z,Wang L,Prabhakar N,Xing Y,Rosenholm JM,Zhang J,Cai K
CaP coated mesoporous polydopamine nanoparticles with responsive membrane permeation ability for combined photothermal and siRNA therapy.
Acta Biomater. 2019 Mar 1;86:416-428. (IF 7.242)

213. Zhang Y,Feng T,Qu J,Sun N,Liu L
Toxicity and haemolytic activity of a newly described dinoflagellate, Heterocapsa bohainensis to the rotifer Brachionus plicatilis.
Harmful Algae. 2019 Apr;84:112-118. (IF 3.707)

214. Duan W,Hu J,Liu Y
Ketamine inhibits colorectal cancer cells malignant potential via blockage of NMDA receptor.
Exp Mol Pathol. 2019 Apr;107:171-178. (IF 2.28)

215. Zhong C,Mai Y,Gao H,Zhou W,Zhou D
Mitochondrial targeting of TR3 is involved in TPA induced apoptosis in breast cancer cells.
Gene. 2019 Apr 20;693:61-68. (IF 2.984)

216. Dong G,Liang F,Sun B,Wang C,Liu Y,Guan X,Yang B,Xiu C,Yang N,Liu F,Lu T,Han W
Presence and function of stress granules in atrial fibrillation.
PLoS One. 2019 Apr 3;14(4):e0213769. (IF 2.74)

217. Yingshi Ji,Yang Hu,Jinghong Ren,Rajesh Khanna,Yuan Yao,Yang Chen,Qi Li,Li Sun
CRMP2-derived Peptide ST2-104 (R9-CBD3) Protects SH-SY5Y Neuroblastoma Cells Against Aβ 25-35-induced Neurotoxicity by Inhibiting the pCRMP2/NMDAR2B Signaling Pathway
CHEM-BIOL INTERACT. 2019 May 25;305:28-39.;doi: 10.1016/j.cbi.2019.03.005. (IF 3.723)

218. Qin Y,Mao W,Pan L,Sun Y,Fan F,Zhao Y,Cui Y,Wei X,Kohama K,Li F,Gao Y
Inhibitory effect of recombinant human CXCL8(3-72)K11R/G31P on atherosclerotic plaques in a mouse model of atherosclerosis.
IMMUNOPHARM IMMUNOT. 2019 Jun;41(3):446-454. (IF 2.352)

219. Chen W,Ju XZ,Lu Y,Ding XW,Miao CH,Chen JW
Propofol improved hypoxia-impaired integrity of blood-brain barrier via modulating the expression and phosphorylation of zonula occludens-1.
CNS Neurosci Ther. 2019 Jun;25(6):704-713. (IF 4.074)

220. Li S,Dai Z,Yang D,Li W,Dai H,Sun B,Liu X,Xie X,Xu R,Zhao X
Targeting β2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2.
Am J Cancer Res. 2019 Jun 1;9(6):1293-1308. eCollection 2019. (IF 5.177)

221. Li M,Fang XZ,Zheng YF,Xie YB,Ma XD,Liu XT,Xia Y,Shao DH
Transient receptor potential vanilloid 4 is a critical mediator in LPS mediated inflammation by mediating calcineurin/NFATc3 signaling.
BIOCHEM BIOPH RES CO. 2019 Jun 11;513(4):1005-1012. (IF 2.985)

222. Wang M,Wu Y,Yu Y,Fu Y,Yan H,Wang X,Li T,Peng W,Luo D
Rutaecarpine prevented ox-LDL-induced VSMCs dysfunction through inhibiting overexpression of connexin 43.
Eur J Pharmacol. 2019 Jun 15;853:84-92. (IF 3.263)

223. Wang R,Wang R,Niu X,Cheng Y,Shang X,Li Y,Li S,Liu X,Shao J
Role of astrocytes-derived d-serine in PFOS-induced neurotoxicity through NMDARs in the rat primary hippocampal neurons.
Toxicology. 2019 Jun 15;422:14-24. (IF 4.099)

224. Qian Yang,Xixi Cai,Muchen Huang,Lee Jia,Shaoyun Wang
Immunomodulatory Effects of Pseudostellaria Heterophylla Peptide on Spleen Lymphocytes via a Ca 2+/CaN/NFATc1/IFN-γ Pathway
Food Funct. 2019 Jun 19;10(6):3466-3476.;doi: 10.1039/c9fo00577c. (IF 4.171)

225. Wang C,Ming B,Wu X,Wu T,Cai S,Hu P,Tang J,Tan Z,Liu C,Zhong J,Zheng F,Dong L
Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response.
EBioMedicine. 2019 Jul;45:578-587. (IF 5.736)

226. Bian X,Wu S,Yin X,Mu L,Yan F,Kong L,Guo Z,Wu L,Ye J
Lyn is involved in host defense against S. agalactiae infection and BCR signaling in Nile tilapia (Oreochromis niloticus).
Dev Comp Immunol. 2019 Jul;96:1-8. (IF 3.192)

227. Zhao H,Chen G,Liang H
Dual PI3K/mTOR Inhibitor, XL765, suppresses glioblastoma growth by inducing ER stress-dependent apoptosis.
ONCOTARGETS THER. 2019 Jul 8;12:5415-5424. (IF 3.337)

228. Wu DP,Bai LR,Lv YF,Zhou Y,Ding CH,Yang SM,Zhang F,Wang YY,Huang JL,Yin XX
A Novel Role of Connexin 40-Formed Channels in the Enhanced Efficacy of Photodynamic Therapy.
Front Oncol. 2019 Jul 9;9:595. (IF 4.848)

229. La X,Zhang L,Yang Y,Li H,Song G,Li Z
Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling.
Cell Signal. 2019 Aug;60:1-16. (IF 3.968)

230. Zhang G,Wang Z,Chen W,Cao Y,Wu J,Qiang G,Ji A,Wu J,Jiang C
Dual effects of gossypol on human hepatocellular carcinoma via endoplasmic reticulum stress and autophagy.
INT J BIOCHEM CELL B. 2019 Aug;113:48-57. (IF 3.673)

231. Fu S,Ding M,Liang Q,Yang Y,Chen M,Wei X,Wang A,Liao S,Ye J
The key differentially expressed genes and proteins related to immune response in the spleen of pufferfish (Takifugu obscurus) infected by Aeromonas hydrophila.
FISH SHELLFISH IMMUN. 2019 Aug;91:1-11. (IF 3.298)

232. Yang Y,Cong H,Du N,Han X,Song L,Zhang W,Li C,Tien P
Mitochondria Redistribution in Enterovirus A71 Infected Cells and Its Effect on Virus Replication.
Virol Sin. 2019 Aug;34(4):397-411. (IF 3.242)

233. Xiaoyu M,Xiuling D,Chunyu Z,Yi S,Jiangchao Q,Yuan Y,Changsheng L
Polyglutamic acid-coordinated assembly of hydroxyapatite nanoparticles for synergistic tumor-specific therapy.
Nanoscale. 2019 Aug 15;11(32):15312-15325. (IF 6.895)

234. Jiang R,Wang M,Shi L,Zhou J,Ma R,Feng K,Chen X,Xu X,Li X,Li T,Sun L
Panax ginseng Total Protein Facilitates Recovery from Dexamethasone-Induced Muscle Atrophy through the Activation of Glucose Consumption in C2C12 Myotubes.
Biomed Res Int. 2019 Aug 6;2019:3719643. (IF 2.276)

235. Li M,Xi P,Xu Y,Wang Z,Han X,Ren W,Phouthapane V,Miao J
Taurine Attenuates Streptococcus uberis-Induced Bovine Mammary Epithelial Cells Inflammation via Phosphoinositides/Ca2+ Signaling.
Front Immunol. 2019 Aug 7;10:1825. (IF 5.085)

236. Zhao C,He R,Shen M,Zhu F,Wang M,Liu Y,Chen H,Li X,Qin R
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells.
Front Pharmacol. 2019 Sep 3;10:968. (IF 4.225)

237. Deng Y,Wang J,Xie G,Zeng X,Li H
Circ-HIPK3 Strengthens the Effects of Adrenaline in Heart Failure by MiR-17-3p – ADCY6 Axis.
Int J Biol Sci. 2019 Sep 7;15(11):2484-2496. (IF 4.858)

238. Zhang L,Wu T,Olatunji OJ,Tang J,Wei Y,Ouyang Z
N6-(2-hydroxyethyl)-adenosine from Cordyceps cicadae attenuates hydrogen peroxide induced oxidative toxicity in PC12 cells.
Metab Brain Dis. 2019 Oct;34(5):1325-1334. (IF 2.726)

239. Ding XW,Sun X,Shen XF,Lu Y,Wang JQ,Sun ZR,Miao CH,Chen JW
Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca2+/CAMK II/ERK/NF-κB signaling pathway.
Acta Pharmacol Sin. 2019 Oct;40(10):1303-1313. (IF 5.064)

240. Song X,Wang F,Xu H,Liang G,Zhou L,Zhang L,Huang F,Jiang G
3-Deoxyglucosone Induces Glucagon-Like Peptide-1 Secretion from STC-1 Cells via Upregulating Sweet Taste Receptor Expression under Basal Conditions.
Int J Endocrinol. 2019 Oct 23;2019:4959646. (IF 2.299)

241. Liu Y,Li J,Chen H,Cai Y,Sheng T,Wang P,Li Z,Yang F,Gu N
Magnet-activatable nanoliposomes as intracellular bubble microreactors to enhance drug delivery efficacy and burst cancer cells.
Nanoscale. 2019 Oct 28;11(40):18854-18865. (IF 6.895)

242. Xu H,Cheng J,Wang X,Liu H,Wang S,Wu J,Xu B,Chen A,He F
Resveratrol pretreatment alleviates myocardial ischemia/reperfusion injury by inhibiting STIM1-mediated intracellular calcium accumulation.
J Physiol Biochem. 2019 Nov;75(4):607-618. (IF 2.952)

243. Song J,Tang Z,Li H,Jiang H,Sun T,Lan R,Wang T,Wang S,Ye Z,Liu J
Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.
J Sex Med. 2019 Nov;16(11):1708-1720. (IF 3.293)

244. Qi J,Wu Q,Zhu X,Zhang S,Chen X,Chen W,Sun Z,Zhu M,Miao C
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
ACTA BIOCH BIOPH SIN. 2019 Nov 18;51(11):1114-1122. (IF 2.836)

245. Feng Q,Liu C,Gao W,Geng XL,Dai N
Salidroside-Mitigated Inflammatory Injury of Hepatocytes with Non-Alcoholic Fatty Liver Disease via Inhibition TRPM2 Ion Channel Activation.
DIABET METAB SYND OB. 2019 Dec 27;12:2755-2763. (IF 2.842)

246. Junzhi Li,Ruining Cheng,Hong Wan
Overexpression of TGR5 alleviates myocardial ischemia/reperfusion injury via AKT/GSK-3β mediated inflammation and mitochondrial pathway
Biosci Rep. 2020 Jan 31;40(1):BSR20193482.;doi: 10.1042/BSR20193482.

247. Xiangnan Kong,Min Li,Kai Shao,Yinrong Yang,Qian Wang,Meijuan Cai
Progesterone induces cell apoptosis via the CACNA2D3/Ca2+/p38 MAPK pathway in endometrial cancer
Oncol Rep. 2020 Jan;43(1):121-132.;doi: 10.3892/or.2019.7396.

248. Chunxia Chen,Wan Chen,Zhihuan Nong,Yichu Nie,Xiaoyu Chen,Xiaorong Pan,Ying Guo,Meicun Yao,Wenbin Deng
Hyperbaric oxygen alleviated cognitive impairments in mice induced by repeated cerebral ischemia-reperfusion injury via inhibition of autophagy
Life Sci. 2020 Jan 15;241:117170.;doi: 10.1016/j.lfs.2019.117170.

249. Lin Che,Huan Yao,Chuan-Li Yang,Ni-Jun Guo,Jing Huang,Zi-Li Wu,Li-Yin Zhang,Yuan-Yuan Chen,Gang Liu,Zhong-Ning Lin,Yu-Chun Lin
Cyclooxygenase-2 modulates ER-mitochondria crosstalk to mediate superparamagnetic iron oxide nanoparticles induced hepatotoxicity: an in vitro and in vivo study
Nanotoxicology. 2020 Mar;14(2):162-180.;doi: 10.1080/17435390.2019.1683245.

250. Zi-Qi Liu,Na Liu,Si-Si Huang,Miao-Miao Lin,Shu Qin,Jun-Chao Wu,Zhong-Qin Liang,Zheng-Hong Qin,Yan Wang
NADPH protects against kainic acid-induced excitotoxicity via autophagy-lysosome pathway in rat striatum and primary cortical neurons
Toxicology. 2020 Apr 15;435:152408.;doi: 10.1016/j.tox.2020.152408.

251. Ru-Jia Xie,Xiao-Xia Hu,Lu Zheng,Shuang Cai,Yu-Si Chen,Yi Yang,Ting Yang,Bing Han,Qin Yang
Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes
World J Gastroenterol. 2020 Apr 7;26(13):1450-1462.;doi: 10.3748/wjg.v26.i13.1450.

252. Ke Wang,Yeliang Lou,Huang Xu,Xiaoming Zhong,Zhen Huang
Harpagide from Scrophularia protects rat cortical neurons from oxygen-glucose deprivation and reoxygenation-induced injury by decreasing endoplasmic reticulum stress
J Ethnopharmacol. 2020 May 10;253:112614.;doi: 10.1016/j.jep.2020.112614.

253. Fan Yang,Li Zou,Yong Wu,Zhihua Wu,Anshu Yang,Hongbing Chen,Xin Li
Structure and allergenicity assessments of bovine β-lactoglobulin treated by sonication-assisted irradiation
J Dairy Sci. 2020 May;103(5):4109-4120.;doi: 10.3168/jds.2019-17070.

254. Hu J,Duan W,Liu Y
Ketamine inhibits aerobic glycolysis in colorectal cancer cells by blocking the NMDA receptor-CaMK II-c-Myc pathway.
CLIN EXP PHARMACOL P . 2020 May;47(5):848-856. (IF 2.092)

255. Dong Xu,Yuxin Wan,Zhihao Li,Chunbao Wang,Qingxia Zou,Chang Du,Yingjun Wang
Tailorable hierarchical structures of biomimetic hydroxyapatite micro/nano particles promoting endocytosis and osteogenic differentiation of stem cells
Biomater Sci. 2020 Jun 21;8(12):3286-3300.;doi: 10.1039/d0bm00443j.

256. Zi-Qiang Liu,Da-Yong Zhou,Yu-Xin Liu,Man-Man Yu,Bing Liu,Liang Song,Xiu-Ping Dong,Hang Qi,Fereidoon Shahidi
Inhibitory effect of natural metal ion chelators on the autolysis of sea cucumber (Stichopus japonicus) and its mechanism
Food Res Int. 2020 Jul;133:109205.;doi: 10.1016/j.foodres.2020.109205.

257. Jia-Peng Li,Wei Wei,Xiao-Xue Li,Ming Xu
Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca 2+ release in vascular smooth muscle cells in diabetic mice
Life Sci. 2020 Aug 15;255:117758.;doi: 10.1016/j.lfs.2020.117758.

258. Jiaxin Li,Qian Zhou,Xin Zhou,Baodong Wei,Yingbo Zhao,Shujuan Ji
Calcium Treatment Alleviates Pericarp Browning of ‘Nanguo’ Pears by Regulating the GABA Shunt After Cold Storage
Front Plant Sci. 2020 Sep 15;11:580986.;doi: 10.3389/fpls.2020.580986.

259. Li Luo,SiYi Liu,Dan Zhang,Fu Wei,NiNa Gu,Yan Zeng,XiaoYing Chen,Shan Xu,ShuKe Liu,Tao Xiang
Chromogranin A (CGA)-derived polypeptide (CGA 47-66) inhibits TNF-α-induced vascular endothelial hyper-permeability through SOC-related Ca 2+ signaling
Peptides. 2020 Sep;131:170297.;doi: 10.1016/j.peptides.2020.170297.

260. Chunyuan Wang,Xianzong Meng,Meiling Meng,Min Shi,Wenping Sun,Xiaojing Li,Xiao Zhang,Ruihao Liu,Ying Fu,Laiyu Song
Oxidative stress activates the TRPM2-Ca 2+-NLRP3 axis to promote PM 2.5-induced lung injury of mice
Biomed Pharmacother. 2020 Oct;130:110481.;doi: 10.1016/j.biopha.2020.110481.

261. Tao Ren,Yi-Jun Tang,Mei-Fang Wang,Han-Sheng Wang,Yan Liu,Xin Qian,Chan Chang,Ming-Wei Chen
Triptolide induces apoptosis through the calcium/calmodulin‑dependent protein kinase kinaseβ/AMP‑activated protein kinase signaling pathway in non‑small cell lung cancer cells
Oncol Rep. 2020 Nov;44(5):2288-2296.;doi: 10.3892/or.2020.7763.

262. Yan Ma,Yizhen Shi,Xiaoting Zou,Qiujue Wu,Jianping Wang
Apoptosis induced by mercuric chloride is associated with upregulation of PERK-ATF4-CHOP pathway in chicken embryonic kidney cells
Poult Sci. 2020 Nov;99(11):5802-5813.;doi: 10.1016/j.psj.2020.06.084.