Hoechst 33258染色液(C1018)

Hoechst 33258染色液

产品编号: C1018

产品包装:50ml
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10ml 50ml

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349.00 10

价格: ¥ 349.00

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产品编号 产品名称 产品包装 产品价格
C1017 Hoechst 33258染色液 10ml 107.00元
C1018 Hoechst 33258染色液 50ml 349.00元

Hoechst 33258,也称bisBenzimide H 33258或HOE 33258。分子式为C25H24N6O·3HCl,分子量为533.88,CAS
Number 23491-45-4。
Hoechst 33258是一种可以穿透细胞膜的蓝色荧光染料,对细胞的毒性较低。
Hoechst 33258染色常用于细胞凋亡检测,染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33258也常用于普通的细胞核染色,或常规的DNA染色。
Hoechst 33258的最大激发波长为346nm,最大发射波长为460nm;Hoechst 33258和双链DNA结合后,最大激发波长为352nm,最大发射波长为461nm。
本Hoechst 33258染色液可直接用于固定细胞或组织的细胞核染色,也可直接用于活细胞或组织的细胞核染色。
包装清单:

产品编号 产品名称 包装
C1018 Hoechst 33258染色液 50ml
说明书 1份

保存条件:
-20℃避光保存,一年有效。
注意事项:
本Hoechst 33258 染色液的浓度经过碧云天的优化,确保可以满足各种常规染色的需要。如需使用特定浓度的Hoechst 33258,请选购碧云天的Hoechst 33258(C1011)。如需染色活细胞或培养的组织,请选购碧云天的Hoechst 33342活细胞染色液(100X) (C1027、C1028或C1029),效果更佳。
荧光染料都存在淬灭的问题,建议染色后尽量当天完成检测。活细胞或组织染色后宜立即观察。
为减缓荧光淬灭可以使用抗荧光淬灭封片液。抗荧光淬灭封片液(P0126)可以向碧云天订购。
Hoechst 33258对人体有害,请注意适当防护。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
1. 对于固定的细胞或组织:
a. 对于细胞或组织样品,固定后,适当洗涤去除固定剂。随后如果需要进行免疫荧光染色,则先进行免疫荧光染色,染色完毕后再按后续步骤进行Hoechst 33258染色。如果不需要进行其它染色,则直接进行后续的Hoechst 33258染色。
b. 对于贴壁细胞或组织切片,加入少量Hoechst 33258染色液,覆盖住样品即可。对于悬浮细胞,至少加入待染色样品体积3倍的染色液,混匀。室温放置3-5分钟。
c. 吸除Hoechst 33258染色液,用TBST、PBS或生理盐水洗涤2-3次,每次3-5分钟。
d. 直接在荧光显微镜下观察或封片后荧光显微镜下观察。细胞发生凋亡时,会看到凋亡细胞的细胞核呈致密浓染,或呈碎块状致密浓染。
2. 对于活细胞或培养的组织:
a. 加入适当量Hoechst 33258染色液,必须充分覆盖住待染色的样品,通常对于六孔板一个孔需加入1ml染色液,对于96孔板一个孔需加入100微升染色液。
b. 在适宜于细胞培养的温度培养20-30分钟。弃染色液,用PBS或培养液洗涤2-3次即可进行荧光检测。细胞发生凋亡时,在荧光显微镜下观察会看到凋亡细胞的细胞核呈致密浓染,或呈碎块状致密浓染。

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Hoechst 33258染色液(C1018)

相关产品请点击如下按钮:
荧光染色
细胞凋亡
细胞凋亡荧光探针

使用本产品的文献:

1. Zhu Chunlei, Zhang Chaodong and Wang Yunjie.
The study of apoptosis induced by methylene blue (MB) on C6 cell and MB enhances BCNU therapy of experimental rat C6 glioma.
《肿瘤》 . 2004;24(1):21-24.

2. Xin-xin Zhao, Li-juan Zhao, Wei-guo Xiao, Jing Lu, Pin-ting Yang and Qing-hong Yu.
C-myc antisense oligodexoynucleotides inhibite synoviocytes proliferation and induce synoviocytes apoptosis.
Chinese Journal of Rheumatology .2004 Feb;8(2):67-72.

3. Guiyun Wang and Xinming Guo.
Effects of radizx astragali on the nitric oxides, free radicals and apoptosis of thymus in aging mice.
Journal of Mudanjiang Medical College .2004 May;25(4):14-5.

4. Li-Xin Zhu, Jing Liu, You-Hua Xie, Yu-Ying Kong, Ye Ye, Chun-Lin Wang, Guang-Di Li, Yuan Wang.
Expression of hepatitis C virus envelope protein 2 induces apoptosis in cultured mammalian cells.
WORLD J GASTROENTERO . 2004 Oct 15;10(20):2972-8. (IF 3.665)

5. Meishu Shen and Wangxi Li.
Effect of angelica on apoptosis in brain cell and thymus index of aging mice.
Journal of Mudanjiang Medical College . 2004 Oct;25(6):9-10.

6. Wang J, Miao J, Sheng W, Yang J.
Construction of pcDNA3.0-ING4 eukaryotic expression vector and study on its function.
《解剖学杂志》 . 2005;28(4):383-6.

7. Ye J, Li A, Liu Q, Wang X, Zhou J.
Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells.
CLIN EXP PHARMACOL P  . 2005 Dec;32(12):1042-8. (IF 2.092)

8. Jiang P, Yan PK, Chen JX, Zhu BY, Lei XY, Yin WD, Liao DF.
High density lipoprotein 3 inhibits oxidized low density lipoprotein-induced apoptosis via promoting cholesterol efflux in RAW264.7 cells.
Acta Pharmacol Sin . 2006 Feb;27(2):151-7. (IF 5.064)

9. Yao G, Yang L, Hu Y, Liang J, Liang J, Hou Y.
Nonylphenol-induced thymocyte apoptosis involved caspase-3 activation and mitochondrial depolarization
Mol Immunol .2006 Mar;43(7):915-26. (IF 3.641)

10. Tang W, Jiang MD, Li XA.
Effects of sp600125 on acetaldehydeinduced apoptosis of hepatic stellate cells and expression of Caspase-3 protein in rats.
《世界华人消化杂志》 . 2006 Mar;116(1-2):129-35.

11. Yingchao Nie, Qian Wang, Changyong Liang, Minggang Fang, Zehua Yu, Xinwen Chen.
Characterization of ORF2 and its encoded protein of the Helicoverpa armigera nucleopolyhedrovirus.
Virus Res . 2006 Mar;116(1-2):129-35. (IF 2.934)

12. Li HG, Liao AH, Ding XF, Zhou H, Xiong CL.
The expression and significance of CATSPER1 in human testis and ejaculated spermatozoa.
Asian J Androl . 2006 May;8(3):301-6. (IF 2.448)

13. Mao WG, Liu ZL, Chen R, Li AP, Zhou JW.
JWA is required for the antiproliferative and pro-apoptotic effects of all-trans retinoic acid in Hela cells.
CLIN EXP PHARMACOL P  . 2006 Sep;33(9):816-24. (IF 2.092)

14. Xiong XL, Jia RH, Yang DP, Ding GH.
Irbesartan attenuates contrast media-induced NRK-52E cells apoptosis.
Pharmacol Res . 2006 Oct;54(4):253-60. (IF 5.893)

15. Zhao Y, Shen S, Guo J, Chen H, Greenblatt DY, Kleeff J, Liao Q, Chen G, Friess H, Leung PS.
Mitogen-activated protein kinases and chemoresistance in pancreatic cancer cells.
J Surg Res . 2006 Dec;136(2):325-35. (IF 1.841)

16. Lin X, Chen X, Wei Y, Zhao J, Fan L, Wen Y, Wu H, Zhao X.
Efficient inhibition of intraperitoneal human ovarian cancer growth and prolonged survival by gene transfer of vesicular stomatitis virus matrix protein in nude mice.
Gynecol Oncol . 2007 Mar;104(3):540-546. (IF 4.623)

17. Yao G, Ling L, Luan J, Ye D, Zhu P.
Nonylphenol induces apoptosis of Jurkat cells by a caspase-8 dependent mechanism.
Int Immunopharmacol . 2007 Apr;7(4):444-53. (IF 3.943)

18. Zhang Y, Ba Y, Liu C, Sun G, Ding L, Gao S, Hao J, Yu Z, Zhang J, Zen K, Tong Z, Xiang Y, Zhang CY.
PGC-1alpha induces apoptosis in human epithelial ovarian cancer cells through a PPARgamma-dependent pathway.
Cell Res . 2007 Apr;17(4):363-73. (IF 20.507)

19. Bao W, Pan H, Lu M, Ni Y, Zhang R, Gong X.
The apoptotic effect of Sarsasapogenin from Anemarrhena asphodeloides on HepG2 human hepatoma cells
Cell Biology International .2007 Sep;31(9):887-92. (IF 2.127)

20. Li X, Peng C, Li L, Ming M, Yang D, Le W.
Glial cell-derived neurotrophic factor protects against proteasome inhibition-induced dopamine neuron degeneration by suppression of endoplasmic reticulum stress and caspase-3 activation.
J GERONTOL A-BIOL . 2007 Sep;62(9):943-50. (IF 5.236)

21. Yan XB, Yang DS, Gao X, Feng J, Shi ZL, Ye Z.
Caspase-8 dependent osteosarcoma cell apoptosis induced by proteasome inhibitor MG132.
Cell Biol Int . 2007 Oct;31(10):1136-43. (IF 2.571)

22. Lin YF, Zhang N, Guo HS, Kong DS, Jiang T, Liang W, Zhao ZH, Tang QQ, Ma D.
Recombinant tissue factor pathway inhibitor induces apoptosis in cultured rat mesangial cells via its Kunitz-3 domain and C-terminal through inhibiting PI3-kinase/Akt pathway.
Apoptosis . 2007 Dec;12(12):2163-73. (IF 4.543)

23. Zhao X, Bai XJ, Feng JW, Dong YJ.
Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells into Neurocytes and Adipocytes Induced in vitro.
《中国农业科学》 . 2008;41(1):229-236.

24. Wu G, Liu ZS, Qian Q, Jiang CQ.
Effects of Berberine on the Growth of Hepatocellular Carcinoma Cell lines.
武汉大学学报 .2008 Jan;29(1):102-105.

25. Xing C, Zhu B, Liu H, Yao H, Zhang L.
Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901.
ACTA BIOCH BIOPH SIN . 2008 Mar;40(3):194-201. (IF 2.836)

26. Wang Q, Wang Y, Liang C, Song J, Chen X.
Identification of a hydrophobic domain of HA2 essential to morphogenesis of Helicoverpa armigera nucleopolyhedrovirus.
J Virol . 2008 Apr;82(8):4072-81. (IF 4.501)

27. Xu HM, Jiang H, Wang J, Luo B, Xie JX.
Over-expressed human divalent metal transporter 1 is involved in iron accumulation in MES23.5 cells.
Neurochem Int . 2008 May;52(6):1044-51. (IF 3.881)

28. Chen P, Yang LL, Yang HS, Wang YS, Li G, Wu Y, Fang F, Liu K, Li J, Zhao X, Hu HZ, Wei YQ.
Synergistic antitumor effect of CXCL10 with hyperthermia.
J CANCER RES CLIN . 2008 Jun;134(6):679-87. (IF 3.656)

29. Shen H, Qin H, Guo J.
Cooperation of metallothionein and zinc transporters for regulating zinc homeostasis in human intestinal Caco-2 cells.
Nutr Res . 2008 Jun;28(6):406-13. (IF 2.767)

30. Qin L, Zhang X, Zhang L, Feng Y, Weng GX, Li MZ, Kong QL, Qian CN, Zeng YX, Zeng MS, Liao DF, Song LB.
Downregulation of BMI-1 enhances 5-fluorouracil-induced apoptosis in nasopharyngeal carcinoma cells.
BIOCHEM BIOPH RES CO . 2008 Jul 4;371(3):531-5. (IF 2.985)

31. Zhou J, Ye J, Zhao X, Li A, Zhou J.
JWA is required for arsenic trioxide induced apoptosis in HeLa and MCF-7 cells via reactive oxygen species and mitochondria linked signal pathway.
TOXICOL APPL PHARM  . 2008 Jul 1;230(1):33-40. (IF 3.616)

32. Yao H, Tao Z, Ai M, Peng L, Wang G, He B, Li Y.
Raman spectroscopic analysis of apoptosis of single human gastric cancer cells.
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33. Yang X, Zhang Y, Zhang L, Zhang L, Mao J.
Silencing alpha-fetoprotein expression induces growth arrest and apoptosis in human hepatocellular cancer cell.
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34. Wang HQ, Xu YX, Zhao XY, Zhao H, Yan J, Sun XB, Guo JC, Zhu CQ.
Overexpression of F(0)F(1)-ATP synthase alpha suppresses mutant huntingtin aggregation and toxicity in vitro.
BIOCHEM BIOPH RES CO . 2009;390(4):1294-8. (IF 2.985)

35. Chen Y, Chen Q, Lu J, Li FH, Tao YY, Liu CH.
Effects of Danggui Buxue Decoction () on lipid peroxidation and MMP-2/9 activities of fibrotic liver in rats.
Chin J Integr Med . 2009 Jan;15(6):435-41. > (IF 1.545)

36. Liu X, Zhang Z, Li P, Zhu L, Wang Y, Wang C.
Polypeptide from Chlamys farreri modulates UVB-induced activation of NF-kappaB signaling pathway and protection HaCaT cells from apoptosis.
REGUL PEPTIDES . 2009 Feb 25;153(1-3):49-55. (IF 1.813)

37. Hu Z, Pan Y, Wang J, Chen J, Li J, Ren L.
Meso-tetra (carboxyphenyl) porphyrin (TCPP) nanoparticles were internalized by SW480 cells by a clathrin-mediated endocytosis pathway to induce high photocytotoxicity.
Biomed Pharmacother . 2009 Feb;63(2):155-64. (IF 4.545)

38. Zhang PY, Zhang WG, He AL, Wang JL, Li WB.
Identification and functional characterization of the novel acute monocytic leukemia associated antigen MLAA-34.
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39. Li ZX, Ouyang KQ, Jiang X, Wang D, Hu Y.
Curcumin induces apoptosis and inhibits growth of human Burkitt’s lymphoma in xenograft mouse model.
Mol Cells . 2009 Mar;27(3):283-9. (IF 4.081)

40. Gong Y, Wu J, Huang Y, Shen S, Han X.
Nonylphenol induces apoptosis in rat testicular Sertoli cells via endoplasmic reticulum stress.
Toxicol Lett . 2009 Apr 25;186(2):84-95. (IF 3.569)

41. Zhang SP, Zhou YJ, Liu Y, Cai YQ.
Effect of liquiritigenin, a flavanone existed from Radix glycyrrhizae on pro-apoptotic in SMMC-7721 cells.
Food Chem Toxicol . 2009 Apr;47(4):693-701. (IF 4.679)

42. Hui L, Ji C, Hui B, Lv T, Ha X, Yang J, Cai W.
The oncoprotein LMO3 interacts with calcium- and integrin-binding protein CIB.
Brain Res . 2009 Apr 10;1265:24-9. (IF 2.733)

43. Guo CJ, Pan Q, Li DG, Sun H, Liu BW.
miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis.
J Hepatol . 2009 Apr;50(4):766-78. (IF 20.582)

44. Zhu C, Huang H, Hua R, Li G, Yang D, Luo J, Zhang C, Shi L, Benovic JL, Zhou N.
Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori.
FEBS Lett . 2009 May 6;583(9):1463-8. (IF 3.057)

45. Wang H, Xu Y, Yan J, Zhao X, Sun X, Zhang Y, Guo J, Zhu C.
Acteoside protects human neuroblastoma SH-SY5Y cells against beta-amyloid-induced cell injury.
Brain Res . 2009 Aug 4;1283:139-47. (IF 2.733)

46. Zeng X, Nan F, Liang C, Song J, Wang Q, Vlak JM, Chen X.
Functional analysis of the Autographa californica nucleopolyhedrovirus IAP1 and IAP2.
SCI CHINA LIFE SCI . 2009 Aug;52(8):761-70. (IF 4.611)

47. Zhang S, Wang J, Song N, Xie J, Jiang H.
Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells.
Neurobiol Aging . 2009 Sep; 30(9):1466-76. (IF 4.347)

48. Yu M, Cai L, Liang M, Huang Y, Gao H, Lu S, Fei J, Huang F.
Alteration of NRSF expression exacerbating 1-methyl-4-phenyl-pyridinium ion-induced cell death of SH-SY5Y cells.
Neurosci Res . 2009 Nov;65(3):236-44. (IF 2.645)

49. Liang W, Cheng J, Liu R, Wang JP, Mu JG, Wang QH, Wang HJ, Ma D.
Peptide corresponding to the C terminus of tissue factor pathway inhibitor inhibits mesangial cell proliferation and activation in vivo.
Peptides . 2009 Dec;30(12):2330-6. (IF 2.843)

50. Qian J, Jiang F, Wang B, Yu Y, Zhang X, Yin Z, Liu C.
Ophiopogonin D prevents H2O2-induced injury in primary human umbilical vein endothelial cells.
J Ethnopharmacol . 2010 Mar 24;128(2):438-45. (IF 3.69)

51. Wang X,Xu J,Ju S,Ni H,Zhu J,Wang H.
Livin gene plays a role in drug resistance of colon cancer cells.
Clinical Biochemistry .2010 May;43(7-8):655–60. (IF 2.43)

52. Li G,Shi H,Huang H,Zhang Y,Wu K,Luo J,Sun Y, Lu J, L. Benovic J and Zhou N.
Internalization of the human nicotinic acid receptor GPR109A is regulated by Gi, GRK2, and arrestin3.
J BIOL CHEM . 2010 Jul 16;285(29):22605-18. (IF 4.238)

53. Zhu W, Chang Y, Wu C, Han Q, Pei R, Lu M, Chen X.
The wild-type hepatitis C virus core inhibits initiation of antigen-specific T- and B-cell immuneresponses in BALB/c mice.
Clin Vaccine Immunol . 2010 Jul;17(7):1139-47. (IF 3.233)

54. Peng H,Zhou JL,Liu SQ,Hu QJ,Ming JH and Qiu B.
Hyaluronic acid inhibits nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes in vitro.
INFLAMMATION RESEARCH .2010 Jul;59(7):519-30. (IF 3.061)

55. Lou C, Yang G, Cai H, Zou M, Xu Z, Li Y, Zhao F, Li W, Tong L, Wang M, Cai B.
2′,4′-Dihydroxychalcone-induced apoptosis of human gastric cancer MGC-803 cells via down-regulation of survivin mRNA.
Toxicol In Vitro . 2010 Aug;24(5):1333-7. (IF 2.959)

56. Chen X, Tang W, Liu S, Yu L, Chen Z.
Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells.
Life Sci . 2010 Aug 14;87(7-8):254-60. (IF 3.647)

57. Xu H, Yan Y, Li L, Peng S, Qu T, Wang B.
Ultraviolet B-induced apoptosis of human skin fibroblasts involves activation of caspase-8 and -3 with increased expression of vimentin.
PHOTODERMATOL PHOTO . 2010 Aug;26(4):198-204. (IF 2.387)

58. Li K, Wang Y, Bai H, Wang Q, Song J, Zhou Y, Wu C, Chen X.
The putative pocket protein binding site of Autographa californica nucleopolyhedrovirus BV/ODV-C42 is required for virus-induced nuclear actin polymerization.
J Virol . 2010 Aug;84(15):7857-68. (IF 4.501)

59. Xiong GS, Sun HL, Wu SM, Mo JZ.
Small interfering RNA against the apurinic or apyrimidinic endonuclease enhances the sensitivityof human pancreatic cancer cells to gemcitabine in vitro.
J DIGEST DIS . 2010 Aug;11(4):224-30. (IF 1.736)

60. Yan YJ, Zheng MZ, Chen ZL, Yu XH, Yang XX, Ding ZL, Xu L.
Studies on preparation and photodynamic mechanism of chlorin P6-,15-N-(cyclohexyl)cycloimide (Chlorin-H) and its antitumor effect for photodynamic therapy in vitro and in vivo.
BIOORG MED CHEM LETT . 2010 Sep 1;18(17):6282-91. (IF 2.572)

61. Liu JT, Guo X, Ma WJ, Zhang YG, Xu P, Yao JF, Bai YD.
Mitochondrial function is altered in articular chondrocytes of an endemic osteoarthritis, Kashin-Beck disease.
OSTEOARTHR CARTILAGE . 2010 Sep;18(9):1218-26. (IF 4.793)

62. Yan YJ, Zheng MZ, Chen ZL, Yu XH, Yang XX, Ding ZL, Xu L.
Studies on preparation and photodynamic mechanism of chlorin P6-13,15-N-(cyclohexyl)cycloimide (Chlorin-H) and its antitumor effect for photodynamic
BIOORG MED CHEM LETT . 2010 Sep 1;18(17):6282-91. (IF 2.572)

63. Ma J, Lu HY, Xia YK, Dong HB, Gu AH, Li ZY, Li Z, Chen AM, Wang XR, Wang SL.
BCL2 Ala43Thr is a functional variant associated with protection against azoospermia in a Han-Chinese population.
Biol Reprod . 2010 Oct;83(4):656-62. (IF 3.322)

64. Wang J, Han X, Yang H, Lu L, Wu Y, Liu X, Guo R, Zhang Y, Zhang Y, Li Q.
A novel RGD-toxin protein, Lj-RGD3, from the buccal gland secretion of Lampetra japonica impactsdiverse biological activities.
Biochimie . 2010 Oct;92(10):1387-96. (IF 3.413)

65. Zheng J,Fang J, Yin YJ,Wang XC,Ren AJ,Bai J,Sun XJ,Yuan WJ,Lin L.
Leptin protects cardiomyocytes from serum‐deprivation‐induced apoptosis by increasing anti‐oxidant defence.
Clinical and Experimental Pharmacology and Physiology .2010 Oct;37(10):955–62. (IF 2.336)

66. Shen L, Lan Z, Sun X, Shi L, Liu Q, Ni J.
Proteomic analysis of lanthanum citrate-induced apoptosis in human cervical carcinoma SiHacells.
Biometals . 2010 Dec;23(6):1179-89. (IF 2.479)

67. Ren J, Zhu D, Liu M, Sun Y, Tian L.
Downregulation of miR-21 modulates Ras expression to promote apoptosis and suppress invasionof Laryngeal squamous cell carcinoma.
Eur J Cancer . 2010 Dec;46(18):3409-16. (IF 7.275)

68. Zhu MT, Wang Y, Feng WY, Wang B, Wang M, Ouyang H, Chai ZF.
Oxidative stress and apoptosis induced by iron oxide nanoparticles in cultured human umbilicalendothelial cells.
J NANOSCI NANOTECHNO . 2010 Dec;10(12):8584-90. (IF 1.134)

69. Du TT,Li L,Song N,Xie JX,Jiang H.
Rosmarinic Acid Antagonized 1-Methyl-4-Phenylpyridinium (MPP+)-Induced Neurotoxicity in MES23. 5 Dopaminergic Cells.
International Journal of Toxicology .2010 Dec;29(6):625-33. (IF 1.223)

70. Wang Y, Hong C, Zhou C, Xu D, Qu HB, Cheng Y.
Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds.
EVID-BASED COMPL ALT . 2011;2011:363052. (IF 1.813)

71. Wang Q, Jiang H, Fan Y, Huang X, Shen J, Qi H, Li Q, Lu X, Shao J.
Phosphorylation of the α-subunit of the eukaryotic initiation factor-2 (eIF2α) alleviates benzo[a]pyrene-7,8-diol-9,10-epoxide induced cell cycle arrest and apoptosis in human cells.
ENVIRON TOXICOL CHEM . 2011 Jan;31(1):18-24. (IF 3.152)

72. Li DL, Liu JJ, Liu BH, Hu H, Sun L, Miao Y, Xu HF, Yu XJ, Ma X, Ren J, Zang WJ.
Acetylcholine inhibits hypoxia-induced tumor necrosis factor-α production via regulation of MAPKsphosphorylation in cardiomyocytes.
J Cell Physiol . 2011 Apr;226(4):1052-9. (IF 5.546)

73. Xu XL, Huang YJ, Wang YQ, Chen XF, Zhang W.
2,3,4′,5-Tetrahydroxystilbene-2-O-β-d-glucoside inhibits platelet-derived growth factor-inducedproliferation of vascular smooth muscle cells by regulating the cell cycle.
CLIN EXP PHARMACOL P  . 2011 May;38(5):307-13. (IF 2.092)

74. Wang F, Ding W, Wang J, Jing R, Wang X, Cong H, Wang Y, Ju S, Wang H.
Identification of microRNA-target interaction in APRIL-knockdown colorectal cancer cells.
Cancer Gene Ther . 2011 Jul;18(7):500-9. (IF 4.534)

75. Li X, Li G, Yu M, Yang Z, Sun J.
The effect ofwhole body low dose radiation on apoptosis of mice leukemia cell.
《潍坊医学院学报》 . 2011 Oct;39(10):1018-29.

76. Muhammad Khan,Bin Zheng,Fei Yi,Azhar Rasul,Zhuyi Gu.
Pseudolaric Acid B Induces Caspase-Dependent and Caspase-Independent Apoptosis in U87 Glioblastoma Cells.
Evidence-Based Complementary and Alternative Medicine ,2012;2012:957568. (IF 1.984)

77. Yuan XH, Lu CL, Yao N, An LS, Yang BQ, Zhang CL, Ma X.
Arsenic induced progesterone production in a caspase-3-dependent manner and changed redoxstatus in preovulatory granulosa cells.
J Cell Physiol . 2012 Jan;227(1):194-203. (IF 5.546)

78. Wang JJ, Li YF, Jin YY, Wang X, Chen TX.
Effects of Epstein-Barr virus on the development of dendritic cells derived from cord bloodmonocytes: an essential role for apoptosis.
Braz J Infect Dis . 2012 Jan-Feb;16(1):19-26. (IF 1.971)

79. Wang PH, Wan DH, Pang LR, Gu ZH, Qiu W, Weng SP, Yu XQ, He JG.
Molecular cloning, characterization and expression analysis of the tumor necrosis factor (TNF) superfamily gene, TNF receptor superfamily gene and lipopolysaccharide-induced TNF-α factor (LITAF) gene from Litopenaeus vannamei.
Dev Comp Immunol .2012 Jan;36(1):39-50. (IF 3.192)

80. Song J, Wang M, Huang H, Luo X, Deng F, Wang H, Hu Z.
Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus.
J Gen Virol . 2012 Feb;93(Pt 2):374-82. (IF 3.376)

81. Li XJ, Zhu CD, Yu W, Wang P, Chen FF, Xia XY, Luo B.
Overexpression of Id3 induces apoptosis of A549 human lung adenocarcinoma cells.
CELL PROLIFERAT . 2012 Feb;45(1):1-8. (IF 5.753)

82. Zhou P, Li H, Wang H, Wang LF, Shi Z.
Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display differentinterferon antagonist activities.
J Gen Virol . 2012 Feb;93(Pt 2):275-81. (IF 3.376)

83. Wang PH, Liang JP, Gu ZH, Wan DH, Weng SP, Yu XQ, He JG.
Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spätzle-like Toll ligands (LvSpz1-3) from Litopenaeus vannamei.
Dev Comp Immunol . 2012 Feb;36(2):359-71. (IF 3.192)

84. Chen YH, Zhao L, Jia XT, Li XY, Li CZ, Yan H, Weng SP, He JG.
Isolation and characterization of cDNAs encoding Ars2 and Pasha homologues, two components of the RNAinterference pathway in Litopenaeus vannamei.
FISH SHELLFISH IMMUN . 2012 Feb;32(2):373-80. (IF 3.298)

85. Li SZ,Li YH,Li JL,Liu C,Yin W,Zhao QX,Lin Z,Ji H and Yang HM.
Construction of pECFP-C1-CIRP and its effect on cold-induced apoptosis in mouse NIH/3T3 cells.
AFR J BIOTECHNOL .2012 Mar;11(21):4938-48. (IF 0.573)

86. Zhang L, Ruan J, Yan L, Li W, Wu Y, Tao L, Zhang F, Zheng S, Wang A, Lu Y.
Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathwayin A549 non-small-cell lung cancer cells.
Molecules . 2012 Mar 26;17(4):3736-50. (IF 3.267)

87. Shi W, Nie D, Jin G, Chen W, Xia L, Wu X, Su X, Xu X, Ni L, Zhang X, Zhang X, Chen J.
BDNF blended chitosan scaffolds for human umbilical cord MSC transplants in traumatic braininjury therapy.
Biomaterials . 2012 Apr;33(11):3119-26. (IF 10.317)

88. Wu C, Deng W, Deng L, Cao L, Qin B, Li S, Wang Y, Pei R, Yang D, Lu M, Chen X.
Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg)determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance.
J Virol . 2012 Apr;86(8):4658-69. 1. (IF 4.501)

89. Tao L, Chen J, Zheng Z, Meng J, Zhang Z, Chen Y, Luo H, Li H, Chen Z, Hu Q, Wang H.
H5N1 influenza virus-like particles produced by transient expression in mammalian cells induce humoral andcellular immune responses in mice.
Can J Microbiol . 2012 Apr;58(4):391-401. (IF 1.793)

90. He D, Ma X, Chen Y, Cai Y, Ru X, Bruce IC, Xia Q, Shi G, Jin J.
Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinasesignaling pathway.
FEBS J . 2012 May;279(10):1834-43. (IF 4.392)

91. Liu M, Yang S, Jin L, Hu D, Wu Z, Yang S.
Chemical Constituents of the Ethyl Acetate Extract of Belamcanda chinensis (L.) DCRoots and Their Antitumor Activities.
Molecules . 2012 May 24;17(5):6156-69. (IF 3.267)

92. Yinghui Dong1, Hanhan Yao2, Zhihua Lin1,Dongli Zhu.
The effects of sperm–egg ratios on polyspermy in the blood clam,Tegillarca granosa.
Aquaculture Research .2012 Jun;43(1):44–52. (IF 1.502)

93. Zeng F, Ni E, Wang S, Lv S, Cao C, Zhang H, Lv H, Chen X, Yan J, Luo F.
A Monoclonal Antibody Against the Catalytic Domain of PTP1B.
HYBRIDOMA (Larchmt). 2012 Jun;31(3):209-13. (IF 0.244)

94. Jiang C, Zhang S, Liu H, Zeng Q, Xia T, Chen Y, Kuang G, Zhao G, Wu X, Zhang X, Wang A.
The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cellsin vitro.
Toxicol Lett . 2012 Jun 20;211(3):325-33. (IF 3.569)

95. Tang W, Zhang Y, Qian C, Yuan Z.
Induction and mechanism of apoptosis by hydroxycamptothecin in human Tenon’s capsulefibroblasts.
INVEST OPHTH VIS SCI . 2012 Jul 24;53(8):4874-80. (IF 3.47)

96. Yang S, Ma J, Xiao J, Lv X, Li X, Yang H, Liu Y, Feng S, Zhang Y.
Arctigenin Anti-Tumor Activity in Bladder Cancer T24 Cell Line Through Induction of Cell-CycleArrest and Apoptosis.
ANAT REC .2012 Aug;295(8):1260-6. (IF 1.634)

97. Liu GY, Yang J, Dai F, Yan WJ, Wang Q, Li XZ, Ding DJ, Cao XY, Zhou B.
CuII ions and the stilbene-chroman hybrid with a catechol moiety synergistically induced DNA damage, and cell cycle arrest and apoptosis of HepG2 cells: an interesting acid/base-promoted prooxidant reaction.
Chemistry . 2012 Aug 27;18(35):11100-6.

98. Zhong Q, Zhou Y, Ye W, Cai T, Zhang X, Deng DY.
Hypoxia-Inducible Factor 1-α-AA-Modified Bone Marrow Stem Cells Protect PC12 Cells fromHypoxia-Induced Apoptosis, Partially Through VEGF/PI3K/Akt/FoxO1 Pathway.
Stem Cells Dev .2012 Sep 20;21(14):2703-17. (IF 3.082)

99. Su W, Chen Y, Zeng W, Liu W, Sun H.
Involvement of Wnt signaling in the injury of murine mesenchymal stem cells exposed to X-radiation.
Int J Radiat Biol . 2012 Sep;88(9):635-41. (IF 2.368)

100. Jiang QH, Liu L, Shen JW, Peel S, Yang GL, Zhao SF, He FM.
Influence of multilayer rhBMP-2 DNA coating on the proliferation and differentiation of MC3T3-E1cells seeded on roughed titanium surface.
J Biomed Mater Res A . 2012 Oct;100(10):2766-74. (IF 3.525)

101. Zhao P, Han T, Guo JJ, Zhu SL, Wang J, Ao F, Jing MZ, She YL, Wu ZH, Ye LB.
HCV NS4B induces apoptosis through the mitochondrial death pathway.
Virus Res . 2012 Oct;169(1):1-7. (IF 2.934)

102. Di S, Tian Z, Qian A, Li J, Wu J, Wang Z, Zhang D, Yin D, Brandi ML, Shang P.
Large gradient high magnetic field affects FLG29.1 cells differentiation to form osteoclast-like cells.
Int J Radiat Biol . 2012 Nov;88(11):806-13. (IF 2.368)

103. Zhang S, Yan H, Li CZ, Chen YH, Yuan FH, Chen YG, Weng SP, He JG.
Identification and function of leucine-rich repeat flightless-I-interacting protein 2 (LRRFIP2) in Litopenaeusvannamei.
PLoS One . 2013;8(2):e57456. (IF 2.74)

104. Ye Y, Li Z, Xing D.
Nitric oxide promotes MPK6-mediated caspase-3-like activation in cadmium-induced Arabidopsisthaliana programmed cell death.
Plant Cell Environ .2013 Jan;36(1):1-15. (IF 6.362)

105. Yu W, Sheng M, Xu R, Yu J, Cui K, Tong J, Shi L, Ren H, Du H.
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibitingendoplasmic reticulum and mitochondrial stress pathways.
J Transl Med . 2013 Jan 29;11:24. (IF 4.124)

106. Zhou L, Huang J, Wang H, Luo J, Zeng L, Xiong K, Chen D.
Expression of Glutamate and GABA during the Process of Rat Retinal Synaptic Plasticity Induced by Acute HighIntraocular Pressure.
ACTA HISTOCHEM CYTOC . 2013 Feb 28;46(1):11-8. (IF 1.39)

107. Yang S, Zhao Q, Xiang H, Liu M, Zhang Q, Xue W, Song B, Yang S.
Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on humancancer cells.
CANCER CELL INT t. 2013 Feb 9;13(1):12. (IF 4.175)

108. Zhang JF, Zhang JG, Kuai XL, Zhang H, Jiang W, Ding WF, Li ZL, Zhu HJ, Mao ZB.
Reactivation of the homeotic tumor suppressor gene CDX2 by 5-aza-2′-deoxycytidine-induced demethylation inhibits cell proliferation and induces caspase-independent apoptosis in gastric cancer cells.
Exp Ther Med . 2013 Mar;5(3):735-741. (IF 1.785)

109. Tang XP, Tang GD, Fang CY, Liang ZH, Zhang LY.
Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells.
WORLD J GASTROENTERO . 2013 Mar 14;19(10):1582-92. (IF 3.665)

110. Huang J, Zhou L, Wang H, Luo J, Zeng L, Xiong K, Chen D.
Distribution of thrombospondins and their neuronal receptor α2δ1 in the rat retina.
Exp Eye Res . 2013 Jun;111:36-49. (IF 3.011)

111. Zhu D, Yu H, He H, Ding J, Tang J, Cao D, Hao L.
Spironolactone inhibits apoptosis in rat mesangial cells under hyperglycaemic conditions via the Wnt signallingpathway.
Mol Cell Biochem . 2013 Aug;380(1-2):185-93. (IF 2.795)

112. Yang YH, Chen K, Li B, Chen JW, Zheng XF, Wang YR, Jiang SD, Jiang LS.
Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway.
Apoptosis . 2013 Nov;18(11):1363-75. (IF 4.543)

113. Li W, Zhao XL, Shang SQ, Shen HQ, Chen X.>
Dual Inhibition of Cdc7 and Cdk9 by PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.
CURR CANCER DRUG TAR .2015;15(3):196-204. (IF 2.912)

114. Jia G, Wang Q, Wang R, Deng D, Xue L, Shao N, Zhang Y, Xia X, Zhi F, Yang Y.
Tubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway.
ONCOTARGETS THER . 2015 Jan 30;8:303-11. (IF 3.337)

115. Wu T, Wang S, Wu J, Lin Z, Sui X, Xu X, Shimizu N, Chen B, Wang X.
Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma.
J EXP CLIN CANC RES . 2015 Feb 15;34:17. (IF 7.068)

116. Jiang L, Wang L, Chen L, Cai GH, Ren QY, Chen JZ, Shi HJ, Xie YH.
As2O3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspases.
Int J Clin Exp Med . 2015 Feb 15;8(2):2190-6. (IF 0.166)

117. Li RL, Huang JJ, Shi YQ, Hu A, Lu ZY, Weng L, Wang SQ, Han YP, Zhang L, Hao CN, Duan JL.
Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia.
Am J Transl Res . 2015 Mar 15;7(3):430-44. (IF 3.375)

118. Zhang K, Wang X, Wang C, Zheng H, Li T, Xiao S, Wang M, Fei C, Zhang L, Xue F.
Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites.
ENVIRON TOXICOL CHEM .2015 Mar;39(2):555-67. (IF 3.152)

119. Wu D, Hu Q, Liu X, Pan L, Xiong Q, Zhu YZ.
Hydrogen sulfide protects against apoptosis under oxidative stress through SIRT1 pathway in H9c2 cardiomyocytes.
NITRIC OXIDE-BIOL CH . 2015 Apr 30;46:204-12. (IF 3.311)

120. Wang X, Jiang P, Wang P, Yang CS, Wang X, Feng Q.
EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer.
PLoS One . 2015 Apr 30;10(4):e0125402. (IF 2.74)

121. Peng X, Zhuang DD, Guo QS.
Induction of S phase arrest and apoptosis by ethyl acetate extract from Tetrastigma hemsleyanum in human hepatoma HepG2 cells.
TUMOR BIOL  . 2015 Apr;36(4):2541-50. (IF 3.65)

122. Xu L, Liu JH, Zhang J, Zhang N, Wang ZH.
Blockade of autophagy aggravates endoplasmic reticulum stress and improves Paclitaxel cytotoxicity in human cervical cancer cells.
Cancer Res Treat . 2015 Apr;47(2):313-21. (IF 3.761)

123. Fu X, Liu Y, Zhuang C, Liu L, Cai Z, Huang W.
Synthetic artificial microRNAs targeting UCA1-MALAT1 or c-Myc inhibit malignant phenotypes of bladder cancer cells T24 and 5637.
Mol Biosyst . 2015 May;11(5):1285-9. (IF 3.336)

124. Dai JQ, Huang YG, He AN.
Dihydromethysticin kavalactone induces apoptosis in osteosarcoma cells through modulation of PI3K/Akt pathway, disruption of mitochondrial membrane potential and inducing cell cycle arrest.
INT J CLIN EXP PATHO . 2015 May 1;8(5):4356-66. (IF 0.252)

125. Luo Q, Liu X, Zheng Y, Zhao Y, Zhu J, Zou L.
Ephrin-B2 mediates trophoblast-dependent maternal spiral artery remodeling in first trimester.
Placenta . 2015 May;36(5):567-74. (IF 3.177)

126. Lu J, Cao Y, Cheng K, Xu B, Wang T, Yang Q, Yang Q, Feng X, Xia Q.
Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status.
Exp Cell Res . 2015 Jun 10;334(2):194-206. (IF 3.383)

127. Yan L, Wang C, Lin B, Liu J, Liu D, Hou R, Wang Y, Gao L, Zhang S, Iwamori M.
Lewis y enhances CAM-DR in ovarian cancer cells by activating the FAK signaling pathway and upregulating Bcl-2/Bcl-XL expression.
Biochimie . 2015 Jun;113:17-25. (IF 3.413)

128. Yang JA, Li JQ, Shao LM, Yang Q, Liu BH, Wu TF, Wu P, Yi W, Chen QX.
Puerarin inhibits proliferation and induces apoptosis in human glioblastoma cell lines.
Int J Clin Exp Med . 2015 Jun 15;8(6):10132-42. (IF 0.166)

129. Wu L, Dai J, Zhao X, Chen Y, Wang G, Li K.
Chloroquine enhances replication of influenza A virus A/WSN/33 (H1N1) in dose-, time-, and MOI-dependent manners in human lung epithelial cells A549.
J Med Virol . 2015 Jul;87(7):1096-103. (IF 2.021)

130. Zhuang CL, Fu X, Liu L, Liu YC, Huang WR, Cai ZM.
Synthetic miRNA sponges driven by mutant hTERT promoter selectively inhibit the progression of bladder cancer.
TUMOR BIOL  . 2015 Jul;36(7):5157-63. (IF 3.65)

131. Zeng X, Tan X.
Epigallocatechin-3-gallate and zinc provide anti-apoptotic protection against hypoxia/reoxygenation injury in H9c2 rat cardiac myoblast cells.
Mol Med Rep . 2015 Aug;12(2):1850-6. (IF 2.1)

132. Zuo N, Zheng X, Liu H, Ma X.
Fenofibrate, a PPARα agonist, protect proximal tubular cells from albumin-bound fatty acids induced apoptosis via the activation of NF-kB.
INT J CLIN EXP PATHO . 2015 Sep 1;8(9):10653-61. (IF 0.252)

133. Wang LY, Li X, Han YZ.
Neuroprotection by epigallo catechin gallate against bupivacaine anesthesia induced toxicity involves modulation of PI3/Akt/PTEN signalling in N2a and SH-SY5Y cells.
Int J Clin Exp Med . 2015 Sep 15;8(9):15065-75. (IF 0.166)

134. Dong M, Lu Y, Zou Z, Yang H.
Monoacylglycerol lipase inhibitor protects primary cultured neurons against homocysteine-induced impairments in rat caudate nucleus through COX-2 signaling.
Life Sci . 2015 Oct 1;138:64-71. (IF 3.647)

135. Wang W, Yan M, Ji Q, Lu J, Ji Y, Ji J.
Suberoylanilide hydroxamic acid suppresses hepatic stellate cells activation by HMGB1 dependent reduction of NF-κB1.
PeerJ . 2015 Nov 3;3:e1362. (IF 2.379)

136. Peng PA, Wang L, Ma Q, Xin Y, Zhang O, Han HY, Liu XL, Ji QW, Zhou YJ, Zhao YX.
Valsartan protects HK-2 cells from contrast media-induced apoptosis by inhibiting endoplasmic reticulum stress.
Cell Biol Int .2015 Dec;39(12):1408–17. (IF 2.571)

137. Huang L, Du B, Gong Y, Xu H, Lu J, Si X.
Effects of Exogenous Interleukin-9 on the Growth, Proliferation and Activity of Interstitial Cells of CajalCultured in vitro.
Digestion . 2016;94(3):154-165. (IF 2.692)

138. Han H, Yang J, Fei S, Liu Z, Zhu S, Dong Q, Gao Z, Wang S, Zhang J.
Protective effect of carbachol postconditioning on hypoxia/reoxygenation-induced injury in human gastric epithelial cells.
Life Sci . 2016 Jan;144:234–42. (IF 3.647)

139. Zhao H, Ma T, Fan B, Yang L, Han C, Luo J, Kong L.
Protective effect of trans-δ-viniferin against high glucose-induced oxidative stress in human umbilical vein endothelial cells through the SIRT1 pathway.
FREE RADICAL RES . 2016 Jan;50(1):68-83. (IF 2.839)

140. Wu C, Hu Y, Fan L, Wang H, Sun Z, Deng S, Liu Y, Hu C.
Ctenopharyngodon idella PKZ facilitates cell apoptosis through phosphorylating eIF2α.
Mol Immunol . 2016 Jan;69:13-23. (IF 3.641)

141. Pan C, Hu YF, Song J, Yi HS, Wang L, Yang YY, Wang YP, Zhang M, Pan MH, Lu C.
Effects of 10-hydroxycamptothecin on intrinsic mitochondrial pathway in silkworm BmN-SWU1 cells.
PESTIC BIOCHEM PHYS . 2016 Feb;127:15-20. (IF 2.751)

142. Wang W, Long L, Wang L, Tan C, Fei X, Chen L, Huang Q, Liang Z.
Knockdown of Cathepsin L promotes radiosensitivity of glioma stem cells both in vivo and in vitro.
Cancer Lett . 2016 Feb 28;371(2):274-84. (IF 7.36)

143. Luo P, Zhang WF, Qian ZX, Xiao LF, Wang H, Zhu TT, Li F, Hu CP, Zhang Z.
MiR-590-5p-meidated LOX-1 upregulation promotes Angiotensin II-induced endothelial cell apoptosis.
BIOCHEM BIOPH RES CO . 2016 Mar 18;471(4):402-8. (IF 2.985)

144. Nie GH, Luo L, Duan HF, Li XQ, Yin MJ, Li Z, Zhang W.
GALNT7, a target of miR-494, participates in the oncogenesis of nasopharyngeal carcinoma.
TUMOR BIOL  .2016 Apr;37(4):4559–67. (IF 3.65)

145. Jiang Q, Liu Y, Duan D, Gou M, Wang H, Wang J, Li Q, Xiao R.
Anti-angiogenic activities of CRBGP from buccal glands of lampreys (Lampetra japonica).
Biochimie . April 2016 Apr;123:7–19. (IF 3.413)

146. Yu J, Xu H, Shen X, Jiang H.
Ghrelin protects MES23.5 cells against rotenone via inhibiting mitochondrial dysfunction and apoptosis.
Neuropeptides . 2016 Apr;56:69-74. (IF 2.411)

147. Xing SF, Jang M, Wang YR, Piao XL.
A new dammarane-type saponin from Gynostemma pentaphyllum induces apoptosis in A549 humanlung carcinoma cells.
Bioorg Med Chem Lett . 2016 Apr 1;26(7):1754-9. (IF 2.572)

148. Li J, Zhang Y, Luan H, Chen X, Han Y, Wang C.
l-carnitine protects human hepatocytes from oxidative stress-induced toxicity through Akt-mediatedactivation of Nrf2 signaling pathway.
CAN J PHYSIOL PHARM . 2016 May;94(5):517-25. (IF 1.946)

149. Liang Y, Ji J, Lin Y, He Y, Liu J.
The Ganglioside GM-1 Inhibits Bupivacaine-Induced Neurotoxicity in Mouse Neuroblastoma Neuro2aCells.
Cell Biochem Funct . 2016 Aug;34(6):455-62. (IF 2.632)

150. Jiang JM, Wang L, Gu HF, Wu K, Xiao F, Chen Y, Guo RM, Tang XQ.
Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance ofEndogenous H2S Generation.
Neurochem Res . 2016 Aug;41(8):2140-8. (IF 3.038)

151. Li J, Li J, Aipire A, Gao L, Huo S, Luo J, Zhang F.
Phenylethanoid Glycosides from Cistanche tubulosa Inhibits the Growth of B16-F10 Cells both in Vitroand in Vivo by Induction of Apoptosis via Mitochondria-dependent Pathway.
J Cancer .2016 Sep 12;7(13):1877-1887. (IF 3.565)

152. Liu X, Bi Y.
Y-27632 Increases Sensitivity of PANC-1 Cells to EGCG in Regulating Cell Proliferation and Migration.
MED SCI MONITOR . 2016 Oct 3;22:3529-3534. (IF 1.918)

153. Ji BL, Xia LP, Zhou FX, Mao GZ, Xu LX.
Aconitine induces cell apoptosis in human pancreatic cancer via NF-κB signaling pathway.
EUR REV MED PHARMACO . 2016 Dec;20(23):4955-4964. (IF 3.024)

154. Yu N, Xiong Y, Wang C.
Bu-Zhong-Yi-Qi Decoction,the Water Extract of Chinese Traditional Herbal Medicine, EnhancesCisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy.
Biomed Res Int . 2017;2017:3692797. (IF 2.276)

155. Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stemcells.
BIOCHEM BIOPH RES CO . 2017 Jan 1;482(1):15-21. (IF 2.985)

156. Chen L, Wang L, Yan J, Ma C, Lu J, Chen G, Chen S, Su F, Wang W, Su X.
131I-labeled monoclonal antibody targeting neuropilin receptor type-2 for tumor SPECT imaging.
Int J Oncol . 2017 Feb;50(2):649-659. (IF 3.899)

157. Jiang Q, Li Q, Han J, Gou M, Zheng Y, Li B, Xiao R, Wang J.
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migrationand invasion of human HeyA8 cells via FAK pathway.
J PATHOL . 2017 Mar;96:652-668. (IF 5.979)

158. Luo H, Yang S, Hong D, Xue W, Xie P.
Synthesis andin vitro antitumor activity of (1E,4E)-1-aryl-5-(2-((quinazolin-4-yl)oxy)phenyl)-1,4-pentadien-3-one derivatives.
Chem Cent J . 2017 Mar 15;11:23. (IF 2.493)

159. Liu F, Li X, Yue H, Ji J, You M, Ding L, Fan H, Hou Y.
TLR-Induced SMPD3 Defects Enhance Inflammatory Response of B Cell and Macrophage in the Pathogenesis of SLE.
Scand J Immunol . 2017 Nov;86(5):377-388. (IF 2.717)

160. Shangguan WJ, Zhang YH, Li ZC, Tang LM, Shao J, Li H.
Naringin inhibits vascularendothelialcell apoptosis viaendoplasmicreticulumstress andmitochondrial mediated pathways and promotes intraosseous angiogenesis in ovariectomized rats.
Int J Mol Med . 2017 Dec;40(6):1741-1749. (IF 3.098)

161. Liu D,You P,Luo Y,Yang M,Liu Y
Galangin Induces Apoptosis in MCF-7 Human Breast Cancer Cells Through Mitochondrial Pathway and Phosphatidylinositol 3-Kinase/Akt Inhibition.
Pharmacology . 2018;102(1-2):58-66. (IF 1.625)

162. Lu K,Rui G,Liu F,Yang L,Deng X,Shi S,Li Q
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Oncol Lett . 2018 Jan;15(1):338-346. (IF 2.311)

163. Huang L,Huang K,Ning H
Hispidulin prevents sevoflurane- Induced memory dysfunction in aged rats.
Biomed Pharmacother. 2018 Jan;97:412-422. (IF 4.545)

164. Li L,Li W,Wang C,Yan X,Wang Y,Niu C,Zhang X,Li M,Tian H,Yao C,Jin H,Han F,Xu D,Han W,Li D,Cui J
Adoptive transfer of natural killer cells in combination with chemotherapy improves outcomes of patients with locally advanced colon carcinoma.
Cytotherapy. 2018 Jan;20(1):134-148. (IF 4.218)

165. Zou WW,Xu SP
Galangin inhibits the cell progression and induces cell apoptosis through activating PTEN and Caspase-3 pathways in retinoblastoma.
Biomed Pharmacother. 2018 Jan;97:851-863. (IF 4.545)

166. Xu H,Wang Z,Sun Z,Ni Y,Zheng L
GATA4 protects against hyperglycemia‑induced endothelial dysfunction by regulating NOX4 transcription.
Mol Med Rep. 2018 Jan;17(1):1485-1492. (IF 2.1)

167. Yang X,Lu Z,Wu H,Li W,Zheng L,Zhao J
Collagen-alginate as bioink for three-dimensional (3D) cell printing based cartilage tissue engineering.
MAT SCI ENG C-MATER . 2018 Feb 1;83:195-201. (IF 5.88)

168. Duan D,Wang H,Zhou R,Jiang Q,Xiao R
The PR-1 domain accounts for the anti-angiogenic activity of a cysteine-rich secretory protein member from the buccal glands of Lampetra japonica.
Int J Biol Macromol. 2018 Feb;107(Pt B):2102-2112. (IF 5.162)

169. Meng PP,Li Z,Wang SY,Zhou WW,Samiullah M,Chen N,Luo FH,Wu T,Yan JH
Preparation, Purification, and Identification of a Monoclonal Antibody Against the C-Terminal Domain of Semaphorin3F.
Monoclon Antib Immunodiagn Immunother. 2018 Feb;37(1):52-58.

170. Zhou RP,Ni WL,Dai BB,Wu XS,Wang ZS,Xie YY,Wang ZQ,Yang WJ,Ge JF,Hu W,Chen FH
ASIC2a overexpression enhances the protective effect of PcTx1 and APETx2 against acidosis-induced articular chondrocyte apoptosis and cytotoxicity.
Gene. 2018 Feb 5;642:230-240. (IF 2.984)

171. Wang CG,Lou YT,Tong MJ,Zhang LL,Zhang ZJ,Feng YZ,Li S,Xu HZ,Mao C
Asperosaponin VI promotes angiogenesis and accelerates wound healing in rats via up-regulating HIF-1α/VEGF signaling.
Acta Pharmacol Sin . 2018 Mar;39(3):393-404. (IF 5.064)

172. Zhang J,Zhang Z,Shu B,Cui G,Zhong G
Cytotoxic and Apoptotic Activity of the Novel Harmine Derivative ZC-14 in Sf9 Cells.
Int J Mol Sci . 2018 Mar 11;19(3). pii: E811. (IF 4.556)

173. Wang C,Mao C,Lou Y,Xu J,Wang Q,Zhang Z,Tang Q,Zhang X,Xu H,Feng Y
Monotropein promotes angiogenesis and inhibits oxidative stress-induced autophagy in endothelial progenitor cells to accelerate wound healing.
J Cell Mol Med. 2018 Mar;22(3):1583-1600. (IF 4.486)

174. Chen W,Yu Y,Yang N,Zhu J,Li K,Li R,Su W,Luo L,Hu L,Chen G,Deng H
Effects of Yangzheng Sanjie Decoction-containing serum mediated by microRNA-7 on cell proliferation and apoptosis in gastric cancer.
Oncol Lett. 2018 Mar;15(3):3621-3629. (IF 2.311)

175. Zhang X,Zhang M,Xiao B,Jiao W,Zhang S,Zhang X
TTF1‑NP induces protective autophagy during apoptosis by inhibiting the Akt/mTOR pathway and activating JNK in human liver cancer cells.
Oncol Rep. 2018 Mar;39(3):1423-1431. (IF 3.417)

176. Zhang B,Cui Y,Wang L,Zhao L,Hou C,Zeng Q,Zhang Z,Yu J,Zhao Y,Nie J,Chen X,Wang A,Liu H
Autophagy regulates high concentrations of iodide-induced apoptosis in SH-SY5Y cells.
Toxicol Lett. 2018 Mar 1;284:129-135. (IF 3.569)

177. Huang RZ,Huang XC,Zhang B,Jia HY,Liao ZX,Wang HS
16-O-caffeoyl-16-hydroxylhexadecanoic acid, a medicinal plant-derived phenylpropanoid, induces apoptosis in human hepatocarcinoma cells through ROS-dependent endoplasmic reticulum stress.
Phytomedicine. 2018 Mar 1;41:33-44. (IF 4.268)

178. Wang W,Qing X,Wang B,Ma K,Wei Y,Shao Z
Tauroursodeoxycholic Acid Protects Nucleus Pulposus Cells from Compression-Induced Apoptosis and Necroptosis via Inhibiting Endoplasmic Reticulum Stress.
EVID-BASED COMPL ALT. 2018 Mar 12;2018:6719460. (IF 1.813)

179. Jiang W,Guo M,Gong M,Chen L,Bi Y,Zhang Y,Shi Y,Qu P,Liu Y,Chen J,Li T
Vitamin A bio-modulates apoptosis via the mitochondrial pathway after hypoxic-ischemic brain damage.
Mol Brain. 2018 Mar 13;11(1):14. (IF 4.686)

180. Li J,Chen Q,He X,Alam A,Ning J,Yi B,Lu K,Gu J
Dexmedetomidine attenuates lung apoptosis induced by renal ischemia-reperfusion injury through α2AR/PI3K/Akt pathway.
J Transl Med. 2018 Mar 23;16(1):78. (IF 4.124)

181. Guan YD,Jiang SL,Yu P,Wen M,Zhang Y,Xiao SS,Xu XJ,Cheng Y
Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of raddeanin A against human breast cancer cells in vitro.
Acta Pharmacol Sin . 2018 Apr;39(4):642-648. (IF 5.064)

182. Du X,Zhu Y,Peng Z,Cui Y,Zhang Q,Shi Z,Guan Y,Sha X,Shen T,Yang Y,Li X,Wang Z,Li X,Liu G
High concentrations of fatty acids and β-hydroxybutyrate impair the growth hormone-mediated hepatic JAK2-STAT5 pathway in clinically ketotic cows.
J Dairy Sci. 2018 Apr;101(4):3476-3487. (IF 3.333)

183. Li A,Gu Y,Li X,Sun H,Zha H,Xie J,Zhao J,Huang M,Chen L,Peng Q,Zhang Y,Weng Y,Zhou L
S100A6 promotes the proliferation and migration of cervical cancer cells via the PI3K/Akt signaling pathway.
Oncol Lett. 2018 Apr;15(4):5685-5693. (IF 2.311)

184. Zhang B,Zhang Y,Liu B,Fang L,Li Y,Meng S
Iso-Osmolar Iodixanol Induces Less Increase in Circulating Endothelial Microparticles In Vivo and Less Endothelial Apoptosis In Vitro Compared with Low-Osmolar Iohexol.
Contrast Media Mol Imaging. 2018 Apr 10;2018:8303609.

185. Wang C,Zhang Z,Xu T,Lou Y,Wang Q,Jin H,Zhang L,Feng Y,Xu H,Mao C
Upregulating mTOR/ERK signaling with leonurine for promoting angiogenesis and tissue regeneration in a full-thickness cutaneous wound model.
Food Funct. 2018 Apr 25;9(4):2374-2385. (IF 4.171)

186. Yuan M,Ning M,Wei P,Hao W,Jing Y,Gu W,Wang W,Meng Q
The function of serpin-2 from Eriocheir sinensis in Spiroplasma eriocheiris infection.
FISH SHELLFISH IMMUN. 2018 May;76:21-26. (IF 3.298)

187. Yang W,Wu F,Luo T,Zhang Y
CCAAT/enhancer binding protein homologous protein knockdown alleviates hypoxia-induced myocardial injury in rat cardiomyocytes exposed to high glucose.
Exp Ther Med. 2018 May;15(5):4213-4222. (IF 1.785)

188. Shi H,Yu F,Mao Y,Ju Q,Wu Y,Bai W,Wang P,Xu R,Jiang M,Shi J
EphA2 chimeric antigen receptor-modified T cells for the immunotherapy of esophageal squamous cell carcinoma.
J Thorac Dis. 2018 May;10(5):2779-2788. (IF 2.046)

189. Yang B,Yan P,Yang GZ,Cao HL,Wang F,Li B
Triptolide reduces ischemia/reperfusion injury in rats and H9C2 cells via inhibition of NF‑κB, ROS and the ERK1/2 pathway.
Int J Mol Med. 2018 Jun;41(6):3127-3136. (IF 3.098)

190. Dai S,Zhang T,Zhang Y,Wang H,Deng F
Zika Virus Baculovirus-Expressed Virus-Like Particles Induce Neutralizing Antibodies in Mice.
Virol Sin. 2018 Jun;33(3):213-226. (IF 3.242)

191. Zhang X,Zhang S,Sun Q,Jiao W,Yan Y,Zhang X
Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3.
Molecules. 2018 Jun 19;23(6). pii: E1482. (IF 3.267)

192. Zhu L,Zou J,Zhao Y,Jiang X,Wang Y,Wang X,Chen B
ER-α36 mediates cisplatin resistance in breast cancer cells through EGFR/HER-2/ERK signaling pathway.
J EXP CLIN CANC RES. 2018 Jun 25;37(1):123. (IF 7.068)

193. Aipire A,Chen Q,Cai S,Li J,Fu C,Ying T,Lu J,Li J
N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway.
Molecules. 2018 Jul 11;23(7). pii: E1687. (IF 3.267)

194. Zhou H,Liu Y,Wang C,Liu L,Wang H,Zhang Y,Long C,Sun X
Triptolide inhibits Epstein-Barr nuclear antigen 1 expression by increasing sensitivity of mitochondria apoptosis of nasopharyngeal carcinoma cells.
J EXP CLIN CANC RES. 2018 Aug 15;37(1):192. (IF 7.068)

195. Yang XJ,Zhao JJ,Chen WJ,Zhang GG,Wang W,Tao HC
Silencing long non-coding RNA, differentiation antagonizing non-protein coding RNA promotes apoptosis and inhibits tumor growth in colon cancer.
Oncol Lett . 2018 Sep;16(3):2865-2872. (IF 2.311)

196. Gao X,Han L,Ding N,Mu Y,Guan P,Hu C,Huang X
Bafilomycin C1 induces G0/G1 cell-cycle arrest and mitochondrial-mediated apoptosis in human hepatocellular cancer SMMC7721 cells.
J ANTIBIOT. 2018 Sep;71(9):808-817. (IF 2.668)

197. Ran X,Liu C,Weng P,Xu X,Lin G,Qi G,Yu N,Xu K,Wu Z,Hu C
Activated grass carp STAT6 up-regulates the transcriptional level and expression of CCL20 and Bcl-xl.
FISH SHELLFISH IMMUN. 2018 Sep;80:214-222. (IF 3.298)

198. Ning M,Yuan M,Liu M,Gao Q,Wei P,Gu W,Wang W,Meng Q
Characterization of cathepsin D from Eriocheir sinensis involved in Spiroplasma eriocheiris infection.
Dev Comp Immunol. 2018 Sep;86:1-8. (IF 3.192)

199. Yang X,Chen L,Liang Y,Si R,Jiang Z,Ma B,Gao P
Knockdown of alpha-fetoprotein expression inhibits HepG2 cell growth and induces apoptosis.
J Cancer Res Ther. 2018 Sep;14(Supplement):S634-S643. (IF 1.326)

200. Zheng J,Zhang M,Weng H
Induction of the mitochondrial NDUFA4L2 protein by HIF-1a regulates heart regeneration by promoting the survival of cardiac stem cell.
BIOCHEM BIOPH RES CO. 2018 Sep 18;503(4):2226-2233. (IF 2.985)

201. Li X,Huang F,Xu X,Hu S
Polyclonal Rabbit Anti-Cancer-Associated Fibroblasts Globulins Induce Cancer Cells Apoptosis and Inhibit Tumor Growth.
Int J Biol Sci. 2018 Sep 7;14(12):1621-1629. (IF 4.858)

202. Mo J,Lin D,Wang J,Li P,Liu W
Apoptosis in HepG2 cells induced by zinc pyrithione via mitochondrial dysfunction pathway: Involvement of zinc accumulation and oxidative stress.
ECOTOX ENVIRON SAFE. 2018 Oct;161:515-525. (IF 4.872)

203. Huang M,Geng Y,Deng Q,Li R,Shao X,Zhang Z,Xu W,Wu Y,Ma Q
Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway.
Int J Oncol. 2018 Oct;53(4):1481-1492. (IF 3.899)

204. Yan ZY,Chen JJ,Duan ZK,Yao GD,Lin B,Wang XB,Huang XX,Song SJ
Racemic phenylpropanoids from the root barks of Ailanthus altissima (Mill.) Swingle with cytotoxicity against hepatoma cells.
Fitoterapia. 2018 Oct;130:234-240. (IF 2.527)

205. Yuan P,Li J,Aipire A,Yang Y,Xia L,Wang X,Li Y,Li J
Cistanche tubulosa phenylethanoid glycosides induce apoptosis in H22 hepatocellular carcinoma cells through both extrinsic and intrinsic signaling pathways.
BMC COMPLEM ALTERN M. 2018 Oct 12;18(1):275. (IF 2.833)

206. Tan XY,Wang X,Liu QS,Xie XQ,Li Y,Li BQ,Li ZQ,Xia QY,Zhao P
Inhibition of silkworm vacuolar-type ATPase activity by its inhibitor Bafilomycin A1 induces caspase-dependent apoptosis in an embryonic cell line of silkworm.
ARCH INSECT BIOCHEM. 2018 Nov;99(3):e21507. (IF 1.536)

207. Wang J,Yan X,Nesengani LT,Ding H,Yang L,Lu W
LPS-induces IL-6 and IL-8 gene expression in bovine endometrial cells “through DNA methylation”.
Gene. 2018 Nov 30;677:266-272. (IF 2.984)

208. Huang RZ,Jin L,Wang CG,Xu XJ,Du Y,Liao N,Ji M,Liao ZX,Wang HS
A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway.
Eur J Pharmacol. 2018 Nov 5;838:157-169. (IF 3.263)

209. Yao GD,Wang J,Song XY,Zhou L,Lou LL,Zhao WY,Lin B,Huang XX,Song SJ
Stereoisomeric guaiacylglycerol-β-coniferyl aldehyde ether induces distinctive apoptosis by downregulation of MEK/ERK pathway in hepatocellular carcinoma cells.
Bioorg Chem. 2018 Dec;81:382-388. (IF 4.831)

210. Chen Q,Su Y,Ju Y,Ma K,Li W,Li W
Astragalosides IV protected the renal tubular epithelial cells from free fatty acids-induced injury by reducing oxidative stress and apoptosis.
Biomed Pharmacother. 2018 Dec;108:679-686. (IF 4.545)

211. Jiang P,Xu C,Chen L,Chen A,Wu X,Zhou M,Haq IU,Mariyam Z,Feng Q
EGCG inhibits CSC-like properties through targeting miR-485/CD44 axis in A549-cisplatin resistant cells.
MOL CARCINOGEN. 2018 Dec;57(12):1835-1844. (IF 3.825)

212. Feng J,Wang X,Li H,Wang L,Tang Z
Silencing of Annexin A1 suppressed the apoptosis and inflammatory response of preeclampsia rat trophoblasts.
Int J Mol Med. 2018 Dec;42(6):3125-3134. (IF 3.098)

213. Xu Z,Huang B,Liu J,Wu X,Luo N,Wang X,Zheng X,Pan X
Combinatorial anti-proliferative effects of tamoxifen and naringenin: The role of four estrogen receptor subtypes.
Toxicology. 2018 Dec 1;410:231-246. (IF 4.099)

214. Huang L,Xiao L,Jung Poudel A,Li J,Zhou P,Gauthier M,Liu H,Wu Z,Yang G
Porous chitosan microspheres as microcarriers for 3D cell culture.
CARBOHYD POLYM. 2018 Dec 15;202:611-620. (IF 7.182)

215. Dai X,Yin C,Zhang Y,Guo G,Zhao C,Wang O,Xiang Y,Zhang X,Liang G
Osthole inhibits triple negative breast cancer cells by suppressing STAT3.
J EXP CLIN CANC RES. 2018 Dec 22;37(1):322. (IF 7.068)

216. Li D,Li X,Li G,Meng Y,Jin Y,Shang S,Li Y
Alpinumisoflavone causes DNA damage in Colorectal Cancer Cells via blocking DNA repair mediated by RAD51.
Life Sci. 2019 Jan 1;216:259-270. (IF 3.647)

217. Wen Y,Chen Y,Li L,Xu M,Tan Y,Li Y,Wang C,Chen Q,Kuang X,Wu Y
Localization and characterization of a putative cysteine desulfurase in Chlamydia psittaci.
J Cell Biochem. 2019 Mar;120(3):4409-4422. (IF 4.237)

218. Shu B,Zhang J,Jiang Z,Cui G,Veeran S,Zhong G
Harmine induced apoptosis in Spodoptera frugiperda Sf9 cells by activating the endogenous apoptotic pathways and inhibiting DNA topoisomerase I activity.
PESTIC BIOCHEM PHYS. 2019 Mar;155:26-35. (IF 2.751)

219. Zhou B,Liu HY,Zhu BL
Protective Role of SOCS3 Modified Bone Marrow Mesenchymal Stem Cells in Hypoxia-Induced Injury of PC12 Cells.
J Mol Neurosci. 2019 Mar;67(3):400-410. (IF 2.678)

220. Pan Z,Qu C,Chen Y,Chen X,Liu X,Hao W,Xu W,Ye L,Lu P,Li D,Zheng Q
Bufotalin induces cell cycle arrest and cell apoptosis in human malignant melanoma A375 cells.
Oncol Rep. 2019 Apr;41(4):2409-2417. (IF 3.417)

221. Zhao C,Wang Y,Peng Z,Sun X,Sun G,Yuan X,Li X,Liu G
Subacute ruminal acidosis suppressed the expression of MCT1 in rumen of cows.
J Cell Physiol. 2019 Jul;234(7):11734-11745. (IF 5.546)

222. Wei DH,Deng JL,Shi RZ,Ma L,Shen JM,Hoffman R,Hu YH,Wang H,Gao JL
Epimedin C Protects H2O2-Induced Peroxidation Injury by Enhancing the Function of Endothelial Progenitor HUVEC Populations.
Biol Pharm Bull. 2019 Sep 1;42(9):1491-1499. (IF 1.863)

223. Pan Z,Zhang X,Yu P,Chen X,Lu P,Li M,Liu X,Li Z,Wei F,Wang K,Zheng Q,Li D
Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells.
Front Oncol. 2019 Sep 4;9:853. (IF 4.848)

224. Zhi L,Song D,Ma L,Feng T
Soyasapogenol B Attenuates Laryngeal Carcinoma Progression through Inducing Apoptotic and Autophagic Cell Death.
ANAT REC. 2019 Oct 3; (IF 1.634)

225. Xueying Zhou,Zhelong Li,Wenqi Sun,Guodong Yang,Changyang Xing,Lijun Yuan
Delivery Efficacy Differences of Intravenous and Intraperitoneal Injection of Exosomes: Perspectives from Tracking Dye Labeled and MiRNA Encapsulated Exosomes
Curr Drug Deliv. 2020;17(3):186-194.;doi: 10.2174/1567201817666200122163251. (IF 1.582)

226. Lili Deng,Jun Fan,Yuedi Ding,Xue Yang,Biao Huang,Zhigang Hu
Target Therapy With Vaccinia Virus Harboring IL-24 For Human Breast Cancer
J Cancer. 2020 Jan 1;11(5):1017-1026.;doi: 10.7150/jca.37590. (IF 3.565)

227. Qianzhu Shi,Yan Zhang,Wen Liu,Hua Xiao,Yifan Qi,Jun Li,Bing Luo
Latent membrane protein 2A inhibits expression level of Smad2 through regulating miR-155-5p in EBV-associated gastric cancer cell lines
J Med Virol. 2020 Jan;92(1):96-106.;doi: 10.1002/jmv.25579. (IF 2.021)

228. Peitao Zhou,Qianqin Li,Shuwen Su,Wenhui Dong,Suyu Zong,Qiong Ma,Xi Yang,Daming Zuo,Shaoyi Zheng,Xianzhong Meng,Dingli Xu,Qingchun Zeng
Interleukin 37 Suppresses M1 Macrophage Polarization Through Inhibition of the Notch1 and Nuclear Factor Kappa B Pathways
Front Cell Dev Biol. 2020 Feb 14;8:56.;doi: 10.3389/fcell.2020.00056. (IF 5.201)

229. Miao Sun,Zhenhui Lu,Peian Cai,Li Zheng,Jinmin Zhao
Salidroside enhances proliferation and maintains phenotype of articular chondrocytes for autologous chondrocyte implantation (ACI) via TGF-β/Smad3 Signal
Biomed Pharmacother. 2020 Feb;122:109388.;doi: 10.1016/j.biopha.2019.109388. (IF 4.545)

230. Yue Geng,Yeting Chen,Wei Sun,Yingmin Gu,Yongjie Zhang,Mei Li,Jiajun Xie,Xuesong Tian
Electroacupuncture Ameliorates Cerebral I/R-Induced Inflammation through DOR-BDNF/TrkB Pathway
EVID-BASED COMPL ALT. 2020 Mar 16;2020:3495836.;doi: 10.1155/2020/3495836. (IF 1.813)

231. Ke Xu,Jun Wang,Hongyu Liu,Jing Zhao,Wenfa Lu
Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway
Molecules. 2020 Mar 9;25(5):1230.;doi: 10.3390/molecules25051230. (IF 3.267)

232. Chengcheng Gai,Mengyu Yu,Zihaoran Li,Yonghong Wang,Dejun Ding,Jie Zheng,Shijun Lv,Weifen Zhang,Wentong Li
Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer
J Cell Physiol. 2020 Apr;235(4):3329-3339.;doi: 10.1002/jcp.29221. (IF 5.546)

233. Ya-Jie Xiong,Yun-Zhen Song,Ying Zhu,Wen-Qing Zuo,Yi-Fan Zhao,Xiao Shen,Wen-Juan Wang,Ya-Li Liu,Jun-Chao Wu,Zhong-Qin Liang
Neuroprotective effects of olanzapine against rotenone-induced toxicity in PC12 cells
Acta Pharmacol Sin. 2020 Apr;41(4):508-515.;doi: 10.1038/s41401-020-0378-6. (IF 5.064)

234. Wangkai Xie,Chao Chen,Zheng Han,Jingjing Huang,Xin Liu,Hongjun Chen,Teming Zhang,Sian Chen,Chenbin Chen,Mingdong Lu,Xian Shen,Xiangyang Xue
CD2AP inhibits metastasis in gastric cancer by promoting cellular adhesion and cytoskeleton assembly
MOL CARCINOGEN. 2020 Apr;59(4):339-352.;doi: 10.1002/mc.23158. (IF 3.825)

235. Xiao Zhu,Ziping Zhao,Canjun Zeng,Bo Chen,Haifeng Huang,Youming Chen,Quan Zhou,Li Yang,Jicheng Lv,Jing Zhang,Daoyan Pan,Jie Shen,Gustavo Duque,Daozhang Cai
HNGF6A Inhibits Oxidative Stress-Induced MC3T3-E1 Cell Apoptosis and Osteoblast Phenotype Inhibition by Targeting Circ_0001843/miR-214 Pathway
CALCIFIED TISSUE INT. 2020 May;106(5):518-532.;doi: 10.1007/s00223-020-00660-z. (IF 3.423)

236. Sunzhi Ye,Wei Wang,Xiaoyan Chen,Yingbin Deng
Sesamin promotes angiogenesis and accelerates wound healing in rats via alleviates TBHP-induced apoptosis in human umbilical vein endothelial cells
BIOSCI BIOTECH BIOCH. 2020 May;84(5):887-897.;doi: 10.1080/09168451.2020.1715200. (IF 1.516)

237. Shengdong Wang,Hengyuan Li,Shi Chen,Zenan Wang,Yuhong Yao,Tao Chen,Zhaoming Ye,Peng Lin
Andrographolide induces apoptosis in human osteosarcoma cells via the ROS/JNK pathway
Int J Oncol. 2020 Jun;56(6):1417-1428.;doi: 10.3892/ijo.2020.5032. (IF 3.899)

238. Chenxu Zhao,Gerd Bobe,Yazhou Wang,Xinyue Zhang,Zhibo Zhao,Shiqi Zhang,Guoquan Sun,Xue Yuan,Xinwei Li,Guowen Liu
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis
Front Vet Sci. 2020 Jul 30;7:394.;doi: 10.3389/fvets.2020.00394. (IF 2.245)

239. Xi Jiang,Yulin Huang
Curcumin Derivative C086 Combined with Cisplatin Inhibits Proliferation of Osteosarcoma Cells
MED SCI MONITOR. 2020 Jul 31;26:e924507.;doi: 10.12659/MSM.924507. (IF 1.918)

240. Yujing Zhang,Huanfeng Bian,Yu Ma,Yuanyuan Xiao,Fang Xiao
Cr(VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes
Biochem J. 2020 Jul 31;477(14):2607-2619.;doi: 10.1042/BCJ20200262. (IF 4.097)

241. Mei Yang,Qingyuan Gui,Jinlei Ma,Lei Qi,Bijun Bao,Yida Huang
Upconversion nanotubes with tunable fluorescence properties based on Gd 2 O 2 S:Ln 3+ (Ln 3+ = Yb 3+, Er 3+) and derivatives for photodynamic therapy
IET Nanobiotechnol. 2020 Jul;14(5):347-356.;doi: 10.1049/iet-nbt.2019.0376. (IF 1.859)

242. Yue-Min Ding,Jiang-Tao Lin,Lu-Mei Fang,Zhang-Qi Lou,Ge-Nan Liang,Xiao-Yue Zhang,Ai-Qing Li,Xiong Zhang
The neuroprotective effect of apigenin against OGD/R injury in rat hippocampal neurons
Pak J Pharm Sci. 2020 Jul;33(4):1527-1533.; (IF 0.562)

243. Qilan Fan,Jialin Li,Chunjuan Xu,Suzhen Wu
Effects of Rehmannia glutinosa polysaccharides on the proliferation and apoptosis of K562 cells
Pak J Pharm Sci. 2020 Jul;33(4):1555-1560.; (IF 0.562)

244. Yu Li,Rong Wang,Lian Xue,Yilin Yang,Feng Zhi
Astilbin protects against cerebral ischaemia/reperfusion injury by inhibiting cellular apoptosis and ROS-NLRP3 inflammasome axis activation
Int Immunopharmacol. 2020 Jul;84:106571.;doi: 10.1016/j.intimp.2020.106571. (IF 3.943)

245. Lina Lai,Yue Liu,Yuanyuan Liu,Ni Zhang,Shilu Cao,Xiaojing Zhang,Di Wu
Role of endoplasmic reticulum oxidase 1α in H9C2 cardiomyocytes following hypoxia/reoxygenation injury
Mol Med Rep. 2020 Aug;22(2):1420-1428.;doi: 10.3892/mmr.2020.11217. (IF 2.1)

246. Guizhi Jia,Zhijun Meng,Caihong Liu,Xinliang Ma,Jia Gao,Jing Liu,Rui Guo,Zheyi Yan,Theodore Christopher,Bernard Lopez,Wenxia Liu,Hongliang Dai,Wayne Bond Lau,Xiangying Jiao,Jianli Zhao,Zi-Xuan Wang,Jimin Cao,Yajing Wang
Nicotine induces cardiac toxicity through blocking mitophagic clearance in young adult rat
Life Sci. 2020 Sep 15;257:118084.;doi: 10.1016/j.lfs.2020.118084. (IF 3.647)

247. Minyi Tian,Xianghuan Wu,Tingya Lu,Xiaoge Zhao,Feng Wei,Guodong Deng,Ying Zhou
Phytochemical Analysis, Antioxidant, Antibacterial, Cytotoxic, and Enzyme Inhibitory Activities of Hedychium flavum Rhizome
Front Pharmacol. 2020 Sep 17;11:572659.;doi: 10.3389/fphar.2020.572659. (IF 4.225)

248. Israa Assani,Ying Du,Chun-Gu Wang,Lei Chen,Pei-Lei Hou,Shi-Feng Zhao,Yan Feng,Ling-Fei Liu,Bo Sun,Yan Li,Zhi-Xin Liao,Ri-Zhen Huang
Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway
Food Funct. 2020 Sep 23;11(9):7717-7726.;doi: 10.1039/d0fo00228c. (IF 4.171)

249. Patrick Wilson,Christopher Stamper,Haley Dugan,Lei Li,Nicholas Asby,Peter Halfmann,Jenna Guthmiller,Nai-Ying Zheng,Min Huang,Olivia Stovicek,Jiaolong Wang,Maria Lucia Madariaga,Kumaran Shanmugarajah,Maud Jansen,Fatima Amanat,Isabelle Stewart,Siriruk Changrob,Henry Utset,Jun Huang,Christopher Nelson,Ya-Nan Dai,Paige Hall,Robert Jedrzejczak,Andrzej Joachimiak,Florian Krammer,Daved Fremont,Yoshihiro Kawaoka
Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2
Res Sq. 2020 Sep 25;rs.3.rs-80476.;doi: 10.21203/rs.3.rs-80476/v1.

250. Ying Shi,Qing Li,Feng Sun,Chenyue Zhu,Sainan Ma,Di Qin,Qingwei Li,Tiesong Li
Lamprey PHB2 maintains mitochondrial stability by tanslocation to the mitochondria under oxidative stress
FISH SHELLFISH IMMUN. 2020 Sep;104:613-621.;doi: 10.1016/j.fsi.2020.06.037. (IF 3.298)

251. Juncheng Liu,Fang Wang,Zebin Weng,Xiaonan Sui,Yong Fang,Xiaozhi Tang,Xinchun Shen
Soybean-derived miRNAs specifically inhibit proliferation and stimulate apoptosis of human colonic Caco-2 cancer cells but not normal mucosal cells in culture
Genomics. 2020 Sep;112(5):2949-2958.;doi: 10.1016/j.ygeno.2020.05.011. (IF 6.205)

252. Rui-Rui Zhang,Na-Na Meng,Chao Liu,Kui-Lin Li,Mu-Xuan Wang,Zhi-Bo Lv,Shu-Ya Chen,Xu Guo,Xin-Kun Wang,Qing Wang,Jin-Yue Sun
PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells
Biomed Pharmacother. 2020 Sep;129:110378.;doi: 10.1016/j.biopha.2020.110378. (IF 4.545)

253. Li Mao,Mei-Ling Zuo,Ai-Ping Wang,Ying Tian,Li-Chen Dong,Tao-Ming Li,Da-Bin Kuang,Gui-Lin Song,Zhong-Bao Yang
Low expression of miR‑532‑3p contributes to cerebral ischemia/reperfusion oxidative stress injury by directly targeting NOX2
Mol Med Rep. 2020 Sep;22(3):2415-2423.;doi: 10.3892/mmr.2020.11325. (IF 2.1)

254. Xu Jia,Ziren Luo,Ying Gao,Hua Liu,Xinghai Liu,Wenli Mai,Hong Liu,Qian Zheng
EGCG Upregulates UCP 3 Levels to Protect MIN 6 Pancreatic Islet Cells from Interleukin-1β-Induced Apoptosis
DRUG DES DEV THER. 2020 Oct 13;14:4251-4261.;doi: 10.2147/DDDT.S270345. (IF 3.216)

255. Jingrui Li,Yuyang Li,Min Liu,Songbo Xie
Modified heptapeptide from tau binds both tubulin and microtubules
Thorac Cancer. 2020 Oct;11(10):2993-2997.;doi: 10.1111/1759-7714.13643. (IF 2.61)

256. Dan Luo,Yuanjiu Miao,Xianliang Ke,Zhongyuan Tan,Chun Hu,Penghui Li,Ting Wang,Yuan Zhang,Jianhong Sun,Yan Liu,Hanzhong Wang,Zhenhua Zheng
Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model
Virol Sin. 2020 Oct;35(5):637-650.;doi: 10.1007/s12250-020-00238-x. (IF 3.242)

257. Xing Fang,TingFei Tan,BeiBei Gao,YingLi Zhao,TingTing Liu,Quan Xia
Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells
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258. Xiangshang Xu,Li Li,Xiaolan Li,Deding Tao,Peng Zhang,Jianping Gong
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259. Bing Hao,Anjie Shi,Xiuhong Li,Jia Li,Zhibin Liu,Hongfeng Yuan
miR-4516 inhibits the apoptosis of RB tumor cells by targeting the PTEN/AKT signaling pathway
Exp Eye Res. 2020 Nov;200:108224.;doi: 10.1016/j.exer.2020.108224. (IF 3.011)

260. Yating Wen,Hongliang Chen,Fangzhen Luo,Lanhua Zhao,Mingyi Shu,Shengmei Su,Yuqi Zhao,Qiulin Huang,Zhongyu Li
Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway
Front Microbiol. 2020 Dec 17;11:593295.;doi: 10.3389/fmicb.2020.593295. (IF 4.235)

261. Shilai Li,Quanlin Qin,Daqing Luo,Wenhui Pan,Yuqing Wei,Yansong Xu,Jijin Zhu,Liming Shang
Hesperidin ameliorates liver ischemia/reperfusion injury via activation of the Akt pathway
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262. Xiaoyu Dong,Zili He,Guangheng Xiang,Leyi Cai,Zhenjiang Xu,Cong Mao,Yongzeng Feng
Paeoniflorin promotes angiogenesis and tissue regeneration in a full-thickness cutaneous wound model through the PI3K/AKT pathway
J Cell Physiol. 2020 Dec;235(12):9933-9945.;doi: 10.1002/jcp.29808. (IF 5.546)

263. Xiaobo Hu,Cong Hu,Jun Liu,Zhuan Wu,Tingting Duan,Zhaohui Cao
1,25-(OH)2D3 protects pancreatic beta cells against H2O2-induced apoptosis through inhibiting the PERK-ATF4-CHOP pathway
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264. Xiangxun Chen,Mengxi Zhou,Wenjie Fan,Mingwei Yang,Lin Yang
Combination of Sodium Cantharidinate with Cisplatin Synergistically Hampers Growth of Cervical Cancer
DRUG DES DEV THER. 2021 Jan 13;15:171-183.;doi: 10.2147/DDDT.S282777. (IF 3.216)

265. Xiujun Deng,Xinghuan Liang,Haiyan Yang,Zhenxing Huang,Xuemei Huang,Chunfeng Liang,Yaqi Kuang,Yingfen Qin,Faquan Lin,Zuojie Luo
Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H 2 O 2 -induced damage via NAMPT and the NF-κB p65 signalling pathway
FEBS Open Bio. 2021 Mar;11(3):866-879.;doi: 10.1002/2211-5463.13067. (IF 2.231)

266. Lili Hou,Xin Yuan,Guannan Le,Ziman Lin,Fang Gan,Haolei Li,Kehe Huang
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Food Chem Toxicol. 2021 Mar;149:112037.;doi: 10.1016/j.fct.2021.112037. (IF 4.679)

267. Chengqun Wei,Xiuzhi Xu,Hongyan Zhu,Xiuyan Zhang,Zhan Gao
Promotive role of microRNA‑150 in hippocampal neurons apoptosis in vascular dementia model rats
Mol Med Rep. 2021 Apr;23(4):257.;doi: 10.3892/mmr.2021.11896. (IF 2.1)

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