Hoechst 33342染色液(C1025)

Hoechst 33342染色液

产品编号: C1025

产品包装:10ml
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10ml 50ml

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101.00 10

价格: ¥ 101.00

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产品编号 产品名称 产品包装 产品价格
C1025 Hoechst 33342染色液 10ml 101.00元
C1026 Hoechst 33342染色液 50ml 341.00元

Hoechst 33342,也称bisBenzimide H 33342或HOE 33342。分子式为C27H28N6O·3HCl·3H2O,分子量为615.99,CAS Number 23491-52-3。
Hoechst 33342是一种可以穿透细胞膜的蓝色荧光染料,对细胞的毒性较低。
Hoechst 33342染色常用于细胞凋亡检测,染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33342也常用于普通的细胞核染色,或常规的DNA染色。
Hoechst 33342的最大激发波长为346nm,最大发射波长为460nm;Hoechst 33342和双链DNA结合后,最大激发波长为350nm,最大发射波长为461nm。
本Hoechst 33342染色液可直接用于固定细胞或组织的细胞核染色,也可直接用于活细胞或组织的细胞核染色。
包装清单:

产品编号 产品名称 包装
C1025 Hoechst 33342染色液 10ml
说明书 1份

保存条件:
-20℃避光保存,一年有效。
注意事项:
本Hoechst 33342 染色液的浓度经过碧云天的优化,确保可以满足各种常规染色的需要。如需使用特定浓度的Hoechst 33342,请选购碧云天的Hoechst 33342(C1022)。如需染色活细胞或培养的组织,请选购碧云天的Hoechst 33342活细胞染色液(100X) (C1027、C1028或C1029),效果更佳。
荧光染料都存在淬灭的问题,建议染色后尽量当天完成检测。活细胞或组织染色后宜立即观察。
为减缓荧光淬灭可以使用抗荧光淬灭封片液。抗荧光淬灭封片液(P0126)可以向碧云天订购。
Hoechst 33342对人体有害,请注意适当防护。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
1. 对于固定的细胞或组织:
a.对于细胞或组织样品,固定后,适当洗涤去除固定剂。随后如果需要进行免疫荧光染色,则先进行免疫荧光染色,染色完毕后再按后续步骤进行Hoechst 33342染色。如果不需要进行其它染色,则直接进行后续的Hoechst 33342染色。
b.对于贴壁细胞或组织切片,加入少量Hoechst 33342染色液,覆盖住样品即可。对于悬浮细胞,至少加入待染色样品体积3倍的染色液,混匀。室温放置3-5分钟。
c. 吸除Hoechst 33342染色液,用TBST、PBS或生理盐水洗涤2-3次,每次3-5分钟。
d.直接在荧光显微镜下观察或封片后荧光显微镜下观察。细胞发生凋亡时,会看到凋亡细胞的细胞核呈致密浓染,或呈碎块状致密浓染。
2. 对于活细胞或培养的组织:
a. 加入适当量Hoechst 33342染色液,必须充分覆盖住待染色的样品,通常对于六孔板一个孔需加入1ml染色液,对于96孔板一个孔需加入100微升染色液。
b. 在适宜于细胞培养的温度培养20-30分钟。弃染色液,用PBS或培养液洗涤2-3次即可进行荧光检测。细胞发生凋亡时,在荧光显微镜下观察会看到凋亡细胞的细胞核呈致密浓染,或呈碎块状致密浓染。

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Hoechst 33342染色液(C1025)

相关产品请点击如下按钮:
荧光染色
细胞凋亡
细胞凋亡荧光探针

使用本产品的文献:

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PLoS One . 2015 Jul 13;10(7):e0132829. (IF 2.74)

75. Hu XL, Guo LP, Song Q, Zhang Q, Chen Y, Wang J, Meng WH, Zhao QC.
Kukoamine B, an amide alkaloid, protects against NMDA-induced neurotoxicity and potential mechanisms in vitro.
Neurochem Int . 2015 Aug;87:66-76. (IF 3.881)

76. Wang DF, Yang HJ, Gu JQ, Cao YL, Meng X, Wang XL, Lin YC, Gao M.
Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis.
Mol Med Rep . 2015 Aug;12(2):2695-700. (IF 2.1)

77. Jiao Y, Ma S, Li J, Shan L, Wang Y, Tian M, Yang Y, Sun J, Ban J, Chen J.
N-Acetyl Cysteine (NAC)-Directed Detoxification of Methacryloxylethyl Cetyl Ammonium Chloride (DMAE-CB).
PLoS One . 2015 Aug 14;10(8):e0135815. (IF 2.74)

78. Chen H, Liao K, Cui-Zhao L, Qiang-Wen F, Feng-Zeng X, Ping-Wu F, Liang-Guo S, Juan-Chen Y.
Cigarette smoke extract induces apoptosis of rat alveolar Type II cells via the PLTP/TGF-β1/Smad2 pathway.
Int Immunopharmacol . 2015 Sep;28(1):707-14. (IF 3.943)

79. Chen JJ, Hong G, Gao LJ, Liu TJ, Cao WJ.
In vitro and in vivo antitumor activity of a novel porphyrin-based photosensitizer for photodynamic therapy.
J CANCER RES CLIN . 2015 Sep;141(9):1553-61. (IF 3.656)

80. Ma NT, Zhou R, Chang RY, Hao YJ, Ma L, Jin SJ, Du J, Zheng J, Zhao CJ, Niu Y, Sun T, Li W, Koike K, Yu JQ, Li YX.
Protective effects of aloperine on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion.
J NAT MED-TOKYO . 2015 Oct;69(4):575-83. (IF 2.055)

81. Cai XY, Xia Y, Yang SH, Liu XZ, Shao ZW, Liu YL, Yang W, Xiong LM.
Ropivacaine- and bupivacaine-induced death of rabbit annulus fibrosus cells in vitro: involvement of the mitochondrial apoptotic pathway.
OSTEOARTHR CARTILAGE . 2015 Oct;23(10):1763-75. (IF 4.793)

82. Yan F, Wang X, Shao L, Ge M, Hu X.
Analysis of UHRF1 expression in human ovarian cancer tissues and its regulation in cancer cell growth.
TUMOR BIOL  . 2015 Nov;36(11):8887-93. (IF 3.65)

83. Zhao Q, Peng Y, Huang K, Lei Y, Liu HL, Tao YY, Liu CH.
Salvianolate Protects Hepatocytes from Oxidative Stress by Attenuating Mitochondrial Injury.
EVID-BASED COMPL ALT . 2016;2016:5408705. (IF 1.813)

84. Zhen N, Yang Q, Wu Q, Zhu X, Wang Y, Sun F, Mei W, Yu Y.
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
CANCER CHEMOTH PHARM . 2016 Jan;77(1):169-80. (IF 2.967)

85. Zhang Q, Fan K, Wang P, Yu J, Liu R, Qi H, Sun H, Cao Y.
Carvacrol induces the apoptosis of pulmonary artery smooth muscle cells under hypoxia.
Eur J Pharmacol . 2016 Jan;770(5):134-6. (IF 3.263)

86. Yu X, Wang J, Liu J, Shen S, Cao Z, Pan J, Zhou S, Pang Z, Geng D, Zhang J.
A multimodal Pepstatin A peptide-based nanoagent for the molecular imaging of P-glycoprotein in the brains of epilepsy rats.
Biomaterials . 2016 Jan;76:173-86. (IF 10.317)

87. Zhen N, Yang Q, Wu Q, Zhu X, Wang Y, Sun F, Mei W, Yu Y .
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agentinhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
CANCER CHEMOTH PHARM . 2016 Jan;77(1):169-80. (IF 2.967)

88. He X, Yu H, Bao X, Cao H, Yin Q, Zhang Z, Li Y.
pH-Responsive Wormlike Micelles with Sequential Metastasis Targeting Inhibit Lung Metastasis of Breast Cancer.
Adv Healthc Mater . 2016 Feb 18;5(4):439-48. (IF 7.367)

89. Shi M, Ren X, Wang X, Wang H, Liu G, Yuan X, Zheng S, Yu L, Pan S, Song G, Guo Q, Li L, Zhang X, Zhang Z, Ding H, Jiang G.
A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
Int J Oncol . 2016 Feb;48(2):734-46. (IF 3.899)

90. Dan J, Sun X, Li W, Zhang Y, Li X, Xu H, Li Z, Tian Z, Guo S, Yao J, Gao W, Tian Y.
5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells.
Ultrasound Med Biol .2016 Feb;5(4):439–48. (IF 2.514)

91. Wang W, Luo J, Liang Y, Li X .
Echinacoside suppresses pancreatic adenocarcinoma cell growth by inducing apoptosis via themitogen-activated protein kinase pathway.
Mol Med Rep . 2016 Mar;13(3):2613-8. (IF 2.1)

92. Zhang LJ, Yan YJ, Liao PY, Margetic D, Wang L, Chen ZL.
Synthesis and antitumor activity evaluation of a novel porphyrin derivative for photodynamic therapy in vitro and in vivo.
TUMOR BIOL  .2016 May;37(5):6923–33. (IF 3.65)

93. Wang Y, Tu L, Li Y, Chen D, Wang S .
Notoginsenoside R1 Protects against Neonatal Cerebral Hypoxic-Ischemic Injury through EstrogenReceptor-Dependent Activation of Endoplasmic Reticulum Stress Pathways.
J Pharmacol Exp Ther . 2016 Jun;357(3):591-605. (IF 3.561)

94. Yang X, Lv Y, Huang K, Luo Y, Xu W .
Zinc inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in human hepatocytes (HepG2 cells).
Food Chem Toxicol . 2016 Jun;92:17-25. (IF 4.679)

95. Gu LL, Zhang XY, Xing WM, Xu JD, Lu H .
Andrographolide-induced apoptosis in human renal tubular epithelial cells: Roles of endoplasmicreticulum stress and inflammatory response.
ENVIRON TOXICOL CHEM . 2016 Jul;45:257-64. (IF 3.152)

96. Zhang XH, Zhang LJ, Sun JJ, Yan YJ, Zhang LX, Chen N, Chen ZL .
Photodynamic efficiency of a chlorophyll-a derivative in vitro and in vivo.
Biomed Pharmacother . 2016 Jul;81:265-72. (IF 4.545)

97. Sun M, Zhou C, Zeng H, Yin F, Wang Z, Yao J, Hua Y, Cai Z.
Benzochloroporphyrin derivative photosensitizer-mediated photodynamic therapy for Ewing sarcoma.
J PHOTOCH PHOTOBIO B . 2016 Jul;160:178-84. (IF 4.383)

98. Zhang LJ, Zhang XH, Liao PY, Sun JJ, Wang L, Yan YJ, Chen ZL .
Antitumor activity evaluation of meso-tetra (pyrrolidine substituted) pentylporphin-mediatedphotodynamic therapy in vitro and in vivo.
J PHOTOCH PHOTOBIO B . 2016 Oct;163:224-31. (IF 4.383)

99. Zhang C, Yu L, Zhou Y, Zhao Q, Liu SQ.
Chitosan oligosaccharides inhibit IL-1β-induced chondrocyte apoptosis via the P38 MAPK signalingpathway.
GLYCOCONJUGATE J . 2016 Oct;33(5):735-44. (IF 2.197)

100. Wang Y, Liu Q, Xu Y, Zhang Y, Lv Y, Tan Y, Jiang N, Cao G, Ma X, Wang J, Cao Z, Yu B, Kou J.
Ginsenoside Rg1 Protects against Oxidative Stress-induced Neuronal Apoptosis through Myosin IIA-actin Related Cytoskeletal Reorganization.
Int J Biol Sci . 2016 Oct 25;12(11):1341-1356. (IF 4.858)

101. Liu Y, Li F, Gao F, Xing L, Qin P, Liang X, Zhang J, Qiao X, Lin L, Zhao Q, Du L .
Periostin promotes the chemotherapy resistance to gemcitabine in pancreatic cancer.
TUMOR BIOL  . 2016 Nov;37(11):15283-15291. (IF 3.65)

102. Bai JA, Jie H, Wei S, Wang S, Guo H, Tang Q .
GART mediates the renewal of intestinal epithelial barrier via p38/p53/PUMA cascade in colitis.
Apoptosis . 2016 Dec;21(12):1386-1397. (IF 4.543)

103. Fan Y, Liu J, Liu D, Zhou Z, Bao Y, Wang J, Zhao Q, Xu Y.
NSCA-1-a novel N-substituted coumalamide derivative-increases Adriamycin sensitivity inHepG2/adriamycin cells through modulating Akt/GSK-3β signaling and p53-dependant apoptotic pathway.
ENVIRON TOXICOL CHEM . 2017 Jan;49:1-7. (IF 3.152)

104. Hu Y, Xiong LL, Zhang P, Wang TH .
Microarray expression profiles of genes in lung tissues of rats subjected to focal cerebral ischemia-induced lung injury following bone marrow-derived mesenchymal stem cell transplantation.
Int J Mol Med . 2017 Jan;39(1):57-70. (IF 3.098)

105. Zhang Y, Wu JY, Weng LH, Li XX, Yu LJ, Xu Y.
Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy.
Neurosci Lett . 2017 Jan 18;638:60-68. (IF 2.274)

106. You F, Li Q, Jin G, Zheng Y, Chen J, Yang H.
Genistein protects against Aβ25-35 induced apoptosis of PC12cells through JNK signaling and modulation of Bcl-2 family messengers.
BMC Neurosci . 2017 Jan 12;18(1):12. (IF 2.811)

107. Wang Z, Liao K, Zuo W, Liu X, Qiu Z, Gong Z, Liu C, Zeng Q, Qian Y, Jiang L, Bu Y, Hong S, Hu G.
Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53-ROS-Mitochondrial Pathway.
Oncol Res . 2017 Jan 2;25(1):123-136. (IF 4.949)

108. Hu Y, Xiong LL, Zhang P, Wang TH.
Microarray expression profiles of genes in lung tissues of rats subjected to focal cerebralischemia-induced lung injury following bone marrow-derived mesenchymal stem cell transplantation.
Int J Mol Med . 2017 Jan;39(1):57-70. (IF 3.098)

109. Fan Y, Liu J, Liu D, Zhou Z, Bao Y, Wang J, Zhao Q, Xu Y.
NSCA-1-a novel N-substituted coumalamide derivative-increases Adriamycin sensitivity in HepG2/adriamycin cells through modulating Akt/GSK-3β signaling and p53-dependant apoptotic pathway.
ENVIRON TOXICOL CHEM . 2017 Jan;49:1-7. (IF 3.152)

110. Chang S, Ruan WC, Xu YZ, Wang YJ, Pang J, Zhang LY, Liao H, Pang T.
The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway.
Acta Pharmacol Sin . 2017 Jan;38(1):29-40. (IF 5.064)

111. Wang Y1, Qiu Y1, Yin S1, Zhang L1, Shi K1, Gao H1, Zhang Z1, He Q1.
A functional nanocarrier that copenetrates extracellular matrix and multiple layers of tumor cells for sequential and deep tumor autophagy inhibitor and chemotherapeutic delivery.
Autophagy . 2017 Feb;13(2):359-370. (IF 9.77)

112. Wen Y, He W, Jiang M, Zeng M, Cai L.
Deriving cells expressing markers of female germ cells from premature ovarian failure patient-specific induced pluripotent stem cells.
Regen Med . 2017 Mar;12(2):143-152. (IF 2.598)

113. Zhai Y1, Li Y2, Wang Y3, Cui J2, Feng K4, Kong X2, Chen L5.
Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance boneformation of osteoblasts and decrease bone resorption of osteoclasts.
Eur J Pharmacol . 2017 Apr 15;801:62-71. (IF 3.263)

114. Wu J, Yang X, Lu H, Liu L, Xu B, Zheng S, Yu B, Jie K, Wan F.
Inhibitory effect and mechanism of exogenous mammalian sterile 20-like kinase 1 on the growth of human colorectal cancer.
Oncol Lett . 2017 Apr;13(4):2656-2664. (IF 2.311)

115. Guo Y, Song Z, Zhou M, Yang Y, Zhao Y, Liu B, Zhang X.
Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway.
ONCOTARGET . 2017 Jun 7;8(32):53276-53287. (IF 5.168)

116. Sun L, Li Y, Jia X, Wang Q, Li Y, Hu M, Tian L, Yang J, Xing W, Zhang W, Wang J, Xu H, Wang L, Zhang D, Ren H.
Neuroprotection byIFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation.
ONCOTARGET . 2017 Jun 20;8(25):40065-40078. (IF 5.168)

117. Xiong LL, Liu F, Lu BT, Zhao WL, Dong XJ, Liu J, Zhang RP, Zhang P, Wang TH.
Bone Marrow Mesenchymal Stem-Cell Transplantation Promotes Functional ImprovementAssociated with CNTF-STAT3 Activation after Hemi-Sectioned Spinal Cord Injury in Tree Shrews.
Front Cell Neurosci . 2017 Jun 28;11:172. (IF 3.921)

118. Wu X, Gao H, Sun W, Yu J, Hu H, Xu Q, Chen X.
Nepetoidin B,a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways.
Phytother Res . 2017 Jul;31(7):1072-1077. (IF 4.087)

119. Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J.
Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Srcdependent NADPH oxidase/ROS pathway.
Exp Cell Res . 2017 Aug 15;357(2):243-251. (IF 3.383)

120. Liu JC, Lai FN, Li L, Sun XF, Cheng SF, Ge W, Wang YF, Li L, Zhang XF, De Felici M, Dyce PW, Shen W.
Di (2-ethylhexyl) phthalate exposure impairs meiotic progression and DNA damage repair in fetalmouse oocytes in vitro.
Cell Death Dis . 2017 Aug 3;8(8):e2966. (IF 6.304)

121. Liu XY, Zhang LJ, Chen Z, Liu LB.
The PTEN inhibitor bpV(pic) promotes neuroprotection against amyloid β-peptide(25-35)-inducedoxidative stress and neurotoxicity.
Neurol Res . 2017 Aug;39(8):758-765. (IF 2.401)

122. Shan ZL, Zhong L, Xiao CL, Gan LG, Xu T, Song H, Yang R, Li L, Liu BZ.
Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells through modulation of MAPKs and c Myc.
Mol Med Rep . 2017 Sep;16(3):3055-3060. (IF 2.1)

123. Hao J, Yang Z, Wang L, Zhang Y, Shu Y, Jiang L, Hu Y, Lv W, Dong P, Liu Y.
Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and inducesapoptosis via PI3K/AKT pathway.
Int J Oncol . 2017 Sep;51(3):823-831. (IF 3.899)

124. Liu X, Qiu Z, Wang Z, Zuo W, Gong Z, Liu C, Zeng Q, Qian Y, Jiang L, Li Y, Bu Y, Hu G.
NFBD1/MDC1 participates inthe regulation of proliferation and apoptosis in human laryngealsquamous cell carcinoma.
Clin Transl Oncol . 2017 Sep 18. (IF 2.737)

125. Ying C, Xiao BD, Qin Y, Wang BR, Liu XY, Wang RW, Fang L, Yan H, Zhou XM, Wang YG.
GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostatecancer stem-like cells in vitro and in vivo.
Acta Pharmacol Sin . 2017 Sep 7. (IF 5.064)

126. Liang J, Wang WF, Xie S, Zhang XL, Qi WF, Zhou XP, Hu JX, Shi Q, Yu RT.
β-transducin repeat-containing E3 ubiquitin protein ligase inhibits migration, invasion and proliferation of glioma cells.
Oncol Lett . 2017 Sep;14(3):3131-3135. (IF 2.311)

127. Geng YD, Zhang C, Lei JL, Yu P, Xia YZ, Zhang H, Yang L, Kong LY.
Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
Biochem Pharmacol . 2017 Oct 15;142:71-86. (IF 4.96)

128. Chen GH, Xu CS, Zhang J, Li Q, Cui HH, Li XD, Chang LP, Tang RJ, Xu JY, Tian XQ, Huang PS, Xu J, Jin C, Yang YJ.
Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1.
Front Pharmacol . 2017 Oct 30;8:775. (IF 4.225)

129. Liu W, Wang X, Liu Z, Wang Y, Yin B, Yu P, Duan X, Liao Z, Chen Y, Liu C, Li X, Dai Y, Tao Z.
SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.
BRIT J CANCER . 2017 Oct 10;117(8):1139-1153. (IF 5.791)

130. Li Y, Sun Y, Cao T, Su Q, Li Z, Huang M, Ouyang R, Chang H, Zhang S, Miao Y.
A cation-exchange controlled core-shell MnS@Bi2S3 theranostic platform for multimodal imaging guided radiation therapy with hyperthermia boost.
Nanoscale . 2017 Oct 5;9(38):14364-14375. (IF 6.895)

131. Qian L, Li X, Ye P, Wang G, Dai W, Liu Y, Gao Q, Shen G.
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKTpathway.
Cytotechnology . 2017 Nov 23. (IF 1.777)

132. Zhao C, Yao X, Chen X, Wu W, Xi F, Yang G, Yu T.
Knockdown of ubiquitin D inhibits adipogenesis duringthe differentiation of porcineintramuscular and subcutaneous preadipocytes.
CELL PROLIFERAT . 2017 Nov 23. (IF 5.753)

133. Yang LL1, Zhao Y1, Luo SM1, Ma JY1, Ge ZJ1, Shen W1, Yin S2.
Toxic Effects and Possible Mechanisms of HydrogenSulfide and/or Ammonia on Porcine OocyteMaturation in vitro.
Toxicol Lett . 2017 Dec 29. pii: S0378-4274(17)31529-1. (IF 3.569)

134. Xiao B, Qin Y, Ying C, Ma B, Wang B, Long F, Wang R, Fang L, Wang Y.
Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model.
Mol Med Rep . 2017 Dec;16(6):9375-9382. (IF 2.1)

135. Li X, Yan X, Wang Y, Wang J, Zhou F, Wang H, Xie W, Kong H.
NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells.
Exp Cell Res . 2017 Dec 16. pii: S0014-4827(17)30668-7. (IF 3.383)

136. Xu Z, Zheng M, Zhang L, Zhang X, Zhang Y, Cui X, Gong X, Xi R, Bai R.
Effect of ATP and Bax onthe apoptosis of Eimeria tenella host cells.
BMC Vet Res . 2017 Dec 28;13(1):399. (IF 1.835)

137. Liu W,Meng Q,Sun Y,Wang C,Huo X,Liu Z,Sun P,Sun H,Ma X,Liu K
Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells.
CELL PHYSIOL BIOCHEM . 2018;51(4):1616-1631. (IF 5.5)

138. Sun J,Guo Y,Zhang Q,Bu S,Li B,Wang Q,Lai D
Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes.
Cell Cycle . 2018;17(13):1591-1601. (IF 3.699)

139. Wang Y,Qin Y,Guo T,Tang C,Liu L,Gao D
High Concentration of Glial Cell Line-Derived Neurotrophic Factor Protects Primary Astrocytes from Apoptosis.
DEV NEUROSCI-BASEL . 2018;40(2):134-144. (IF 3.041)

140. Qian L,Li X,Ye P,Wang G,Dai W,Liu Y,Gao Q,Shen G
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
Cytotechnology . 2018 Feb;70(1):83-94. (IF 1.777)

141. Miao X,Gu Z,Liu Y,Jin M,Lu Y,Gong Y,Li L,Li C
The glucagon-like peptide-1 analogue liraglutide promotes autophagy through the modulation of 5′-AMP-activated protein kinase in INS-1 β-cells under high glucose conditions.
Peptides . 2018 Feb;100:127-139. (IF 2.843)

142. Ouyang G,Xiong L,Liu Z,Lam B,Bui B,Ma L,Chen X,Zhou P,Wang K,Zhang Z,Huang H,Miao X,Chen W,Wen Y
Inhibition of autophagy potentiates the apoptosis-inducing effects of photodynamic therapy on human colon cancer cells.
PHOTODIAGN PHOTODYN . 2018 Mar;21:396-403. (IF 2.894)

143. Ying C,Xiao BD,Qin Y,Wang BR,Liu XY,Wang RW,Fang L,Yan H,Zhou XM,Wang YG
GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostate cancer stem-like cells in vitro and in vivo.
Acta Pharmacol Sin . 2018 Mar;39(3):405-414. (IF 5.064)

144. Sun Y, Wang C, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Peng J, Liu K.
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+-mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
J Cell Physiol . 2018 Apr;233(4):3066-3079. (IF 5.546)

145. Sun Y,Wang C,Meng Q,Liu Z,Huo X,Sun P,Sun H,Ma X,Peng J,Liu K
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
J Cell Physiol . 2018 Apr;233(4):3066-3079. (IF 5.546)

146. Hu YP,Wu ZB,Jiang L,Jin YP,Li HF,Zhang YJ,Ma Q,Ye YY,Wang Z,Liu YC,Chen HZ,Liu YB
STYK1 promotes cancer cell proliferation and malignant transformation by activating PI3K-AKT pathway in gallbladder carcinoma.
INT J BIOCHEM CELL B . 2018 Apr;97:16-27. (IF 3.673)

147. Liu X,Qiu Z,Wang Z,Zuo W,Gong Z,Liu C,Zeng Q,Qian Y,Jiang L,Li Y,Bu Y,Hu G
NFBD1/MDC1 participates in the regulation of proliferation and apoptosis in human laryngeal squamous cell carcinoma.
Clin Transl Oncol . 2018 Apr;20(4):534-541. (IF 2.737)

148. Zhao C,Yao X,Chen X,Wu W,Xi F,Yang G,Yu T
Knockdown of ubiquitin D inhibits adipogenesis during the differentiation of porcine intramuscular and subcutaneous preadipocytes.
CELL PROLIFERAT . 2018 Apr;51(2):e12401. (IF 5.753)

149. Wang S,Cheng Y,Gao Y,He Z,Zhou W,Chang R,Peng Z,Zheng Y,Duan C,Zhang C
SH2B1 promotes epithelial-mesenchymal transition through the IRS1/β-catenin signaling axis in lung adenocarcinoma.
MOL CARCINOGEN . 2018 May;57(5):640-652. (IF 3.825)

150. Feng S,Liu J,Cheng B,Deng A,Zhang H
(-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway.
Exp Ther Med . 2018 May;15(5):4284-4290. (IF 1.785)

151. Gao Y,Han K,Wang Q,Hu Z,Liu Q,Liu L,Zeng K
Development of podophyllotoxin‑loaded nanostructured lipid carriers for the treatment of condyloma acuminatum.
Mol Med Rep . 2018 May;17(5):6506-6514. (IF 2.1)

152. Chu P,He L,Xiong L,Luo L,Huang R,Liao L,Li Y,Zhu Z,Wang Y
Molecular cloning, expression analysis and localization pattern of the MST family in grass carp (Ctenopharyngodon idella).
FISH SHELLFISH IMMUN . 2018 May;76:316-323. (IF 3.298)

153. Han B,Zhang YY,Xu K,Bai Y,Wan LH,Miao SK,Zhang KX,Zhang HW,Liu Y,Zhou LM
NUDCD1 promotes metastasis through inducing EMT and inhibiting apoptosis in colorectal cancer.
Am J Cancer Res. 2018 May 1;8(5):810-823. eCollection 2018. (IF 5.177)

154. Gu LL,Shen ZL,Li YL,Bao YQ,Lu H
Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells.
Mol Cells . 2018 May 31;41(5):401-412. (IF 4.081)

155. Yang B,Bai Y,Yin C,Qian H,Xing G,Wang S,Li F,Bian J,Aschner M,Lu R
Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes.
Arch Toxicol . 2018 Jun;92(6):2093-2108. (IF 5.059)

156. Zhang H,Feng QQ,Gong JH,Ma JP
Anticancer effects of isofraxidin against A549 human lung cancer cells via the EGFR signaling pathway.
Mol Med Rep . 2018 Jul;18(1):407-414. (IF 2.1)

157. Liu Y,Jiang P,Wang G,Liu X,Luo S
Downregulation of RFX1 predicts poor prognosis of patients with small hepatocellular carcinoma.
EJSO-EUR J SURG ONC . 2018 Jul;44(7):1087-1093. (IF 3.959)

158. Yu J,Chen Z,Li Y,Du M,Yan F,Zheng H
Echogenic Chitosan Nanodroplets for Spatiotemporally Controlled Gene Delivery.
J BIOMED NANOTECHNOL . 2018 Jul 1;14(7):1287-1297. (IF 5.068)

159. Zhang GL,Song JL,Zhou Y,Zhang RQ,Cheng SF,Sun XF,Qin GQ,Shen W,Li L
Differentiation of sow and mouse ovarian granulosa cells exposed to zearalenone in vitro using RNA-seq gene expression.
TOXICOL APPL PHARM  . 2018 Jul 1;350:78-90. (IF 3.616)

160. Kang X,Yang MY,Shi YX,Xie MM,Zhu M,Zheng XL,Zhang CK,Ge ZL,Bian XT,Lv JT,Wang YJ,Zhou BH,Tang KL
Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors.
Cell Commun Signal . 2018 Jul 20;16(1):42. (IF 4.344)

161. Zhang GL,Song JL,Ji CL,Feng YL,Yu J,Nyachoti CM,Yang GS
Zearalenone Exposure Enhanced the Expression of Tumorigenesis Genes in Donkey Granulosa Cells via the PTEN/PI3K/AKT Signaling Pathway.
Front Genet . 2018 Jul 31;9:293. (IF 3.258)

162. Chen Z,Ma Y,Pan Y,Zhu H,Yu C,Sun C
MiR-1297 suppresses pancreatic cancer cell proliferation and metastasis by targeting MTDH.
MOL CELL PROBE . 2018 Aug;40:19-26. (IF 1.951)

163. Chen H,Cao J,Zhu Z,Zhang G,Shan L,Yu P,Wang Y,Sun Y,Zhang Z
A Novel Tetramethylpyrazine Derivative Protects Against Glutamate-Induced Cytotoxicity Through PGC1α/Nrf2 and PI3K/Akt Signaling Pathways.
FRONT NEUROSCI-SWITZ . 2018 Aug 15;12:567. (IF 3.707)

164. Zhai QY,Ge W,Wang JJ,Sun XF,Ma JM,Liu JC,Zhao Y,Feng YZ,Dyce PW,De Felici M,Shen W
Exposure to Zinc oxide nanoparticles during pregnancy induces oocyte DNA damage and affects ovarian reserve of mouse offspring.
AGING-US . 2018 Aug 28;10(8):2170-2189. (IF 4.831)

165. Zhang Z,Wei Y,Liu B,Wu Y,Wang H,Xie X,Feng Z,Shao G,Xiong Q
Hsp90/Sec22b promotes unconventional secretion of mature-IL-1β through an autophagosomal carrier in porcine alveolar macrophages during Mycoplasma hyopneumoniae infection.
Mol Immunol . 2018 Sep;101:130-139. (IF 3.641)

166. Teng F,Xu Z,Chen J,Zheng G,Zheng G,Lv H,Wang Y,Wang L,Cheng X
DUSP1 induces apatinib resistance by activating the MAPK pathway in gastric cancer.
Oncol Rep . 2018 Sep;40(3):1203-1222. (IF 3.417)

167. Sun L,Hu L,Zhang P,Li H,Sun J,Wang H,Xie X,Hu J
Silencing of PMEL attenuates melanization via activating lysosomes and degradation of tyrosinase by lysosomes.
BIOCHEM BIOPH RES CO . 2018 Sep 18;503(4):2536-2542. (IF 2.985)

168. Zhao Z,Zhang Y,Tian C,Yin T,Zhang C
Facile dynamic one-step modular assembly based on boronic acid-diol for construction of a micellar drug delivery system.
BIOMATER SCI-UK . 2018 Sep 25;6(10):2605-2618. (IF 6.183)

169. Liu CX,Tan YR,Xiang Y,Liu C,Liu XA,Qin XQ
Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Injury via Attenuation of ROS-Mediated Ca2+ Overload and Mitochondrial Dysfunction in Human Bronchial Epithelial Cells.
Biomed Res Int . 2018 Sep 30;2018:2070971. (IF 2.276)

170. Wei YL,Hua J,Liu XY,Hua XM,Sun C,Bai JA,Tang QY
LncNEN885 inhibits epithelial-mesenchymal transition by partially regulation of Wnt/β-catenin signalling in gastroenteropancreatic neuroendocrine neoplasms.
Cancer Sci . 2018 Oct;109(10):3139-3148. (IF 4.966)

171. Fang SY,Hu CQ,Liu MN,Tao L,Wang Y,Gong MJ,He Y,He TC,Bi Y
Reversibly immortalized hepatic progenitor cell line containing double suicide genes.
Int J Mol Med . 2018 Oct;42(4):1977-1986. (IF 3.098)

172. Chu P,He L,Li Y,Huang R,Liao L,Li Y,Zhu Z,Wang Y
Molecular cloning and functional characterisation of NLRX1 in grass carp (Ctenopharyngodon idella).
FISH SHELLFISH IMMUN . 2018 Oct;81:276-283. (IF 3.298)

173. Liu X,Li P,Hirayama R,Niu Y,Liu X,Chen W,Jin X,Zhang P,Ye F,Zhao T,Liu B,Li Q
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways.
Radiother Oncol . 2018 Oct;129(1):84-94. (IF 4.856)

174. Shen J,Zhou T,Li H,Li W,Wang S,Song Y,Ke K,Cao M
Cab45s inhibits neuronal apoptosis following intracerebral hemorrhage in adult rats.
Brain Res Bull . 2018 Oct;143:36-44. (IF 3.37)

175. Zhang RQ,Sun XF,Wu RY,Cheng SF,Zhang GL,Zhai QY,Liu XL,Zhao Y,Shen W,Li L
Zearalenone exposure elevated the expression of tumorigenesis genes in mouse ovarian granulosa cells.
TOXICOL APPL PHARM  . 2018 Oct 1;356:191-203. (IF 3.616)

176. Zhao X,Qi T,Kong C,Hao M,Wang Y,Li J,Liu B,Gao Y,Jiang J
Photothermal exposure of polydopamine-coated branched Au-Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells.
INT J NANOMED . 2018 Oct 12;13:6413-6428. (IF 5.115)

177. Ma YS,Lv ZW,Yu F,Chang ZY,Cong XL,Zhong XM,Lu GX,Zhu J,Fu D
MicroRNA-302a/d inhibits the self-renewal capability and cell cycle entry of liver cancer stem cells by targeting the E2F7/AKT axis.
J EXP CLIN CANC RES . 2018 Oct 16;37(1):252. (IF 7.068)

178. Huang H,Li H,Shi K,Wang L,Zhang X,Zhu X
TREK‑TRAAK two‑pore domain potassium channels protect human retinal pigment epithelium cells from oxidative stress.
Int J Mol Med . 2018 Nov;42(5):2584-2594. (IF 3.098)

179. Zhu HZ,Hou J,Guo Y,Liu X,Jiang FL,Chen GP,Pang XF,Sun JG,Chen ZT
Identification and imaging of miR-155 in the early screening of lung cancer by targeted delivery of octreotide-conjugated chitosan-molecular beacon nanoparticles.
Drug Deliv . 2018 Nov;25(1):1974-1983. (IF 4.902)

180. Zhong L,Jin J,Zheng D,Guan W,Guo Y,Chen A,Peng Y,Gao Q,Zheng Y,Huang H
Influence of super-hydrophobic silicone rubber substrate on the growth and differentiation of human lens epithelial cells.
J MATER SCI-MATER M . 2018 Nov 13;29(11):176. (IF 2.489)

181. Liu Y,Guan X,Li C,Ni F,Luo S,Wang J,Zhang D,Zhang M,Hu Q
HSV-2 glycoprotein J promotes viral protein expression and virus spread.
Virology . 2018 Dec;525:83-95. (IF 2.819)

182. Yang Y,Fu C,Zhou F,Luo X,Li J,Zhao J,He J,Li X,Li J
Chemical composition, antioxidant and antitumor activities of sub-fractions of wild and cultivated Pleurotus ferulae ethanol extracts.
PeerJ . 2018 Dec 20;6:e6097. (IF 2.379)

183. Sun ZY,Zhang P,Wang JJ,Liu JC,Li L,Shen W,Zhai QY
Melatonin alleviates meiotic defects in fetal mouse oocytes induced by Di (2-ethylhexyl) phthalate in vitro.
AGING-US . 2018 Dec 26;10(12):4175-4187. (IF 4.831)

184. Shi R,Xiang W,Kang X,Zhang L,Wang J,Miao H,He F
Alteration of Adaptive Immunity in a Colorectal Peritoneal Carcinomatosis Model.
J Cancer. 2019 Jan 1;10(2):367-377. (IF 3.565)

185. Chen X,Lv C,Zhu X,Lin W,Wang L,Huang Z,Yang S,Sun J
MicroRNA-504 modulates osteosarcoma cell chemoresistance to cisplatin by targeting p53.
Oncol Lett. 2019 Feb;17(2):1664-1674. (IF 2.311)

186. Jiang Y,Zhang T,Vallesi A,Yang X,Gao F
Time-course analysis of nuclear events during conjugation in the marine ciliate Euplotes vannus and comparison with other ciliates (Protozoa, Ciliophora).
Cell Cycle . 2019 Feb;18(3):288-298. (IF 3.699)

187. Tian J,Rui K,Hong Y,Wang X,Xiao F,Lin X,Ma J,Guo H,Xu H,Ma K,Xu D,Liu D,Zhao Y,Lu L,Wang S
Increased GITRL Impairs the Function of Myeloid-Derived Suppressor Cells and Exacerbates Primary Sjögren Syndrome.
J Immunol . 2019 Mar 15;202(6):1693-1703. (IF 4.886)

188. Su W,Tang J,Wang Y,Sun S,Shen Y,Yang H
Long non-coding RNA highly up-regulated in liver cancer promotes epithelial-to-mesenchymal transition process in oral squamous cell carcinoma.
J Cell Mol Med. 2019 Apr;23(4):2645-2655. (IF 4.486)

189. Liu G,Wang Y,Zheng W,Cheng H,Zhou R
P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice.
Int J Biol Sci. 2019 May 20;15(7):1383-1395. (IF 4.858)

190. Liu H,Chen J,Li X,Deng Z,Gao P,Li J,Ren T,Huang L,Yang Y,Zhong S
Amphipathic β-cyclodextrin nanocarriers serve as intelligent delivery platform for anticancer drug.
COLLOID SURFACE B. 2019 Aug 1;180:429-440. (IF 4.389)

191. Zeng Z,Liu Y,Zheng W,Liu L,Yin H,Zhang S,Bai H,Hua L,Wang S,Wang Z,Li X,Xiao J,Yuan Q,Wang Y
MicroRNA-129-5p alleviates nerve injury and inflammatory response of Alzheimer’s disease via downregulating SOX6.
Cell Cycle. 2019 Nov;18(22):3095-3110. (IF 3.699)

192. Li X,Liu H,Li J,Deng Z,Li L,Liu J,Yuan J,Gao P,Yang Y,Zhong S
Micelles via self-assembly of amphiphilic beta-cyclodextrin block copolymers as drug carrier for cancer therapy.
COLLOID SURFACE B. 2019 Nov 1;183:110425. (IF 4.389)

193. Song-Yun Chu,Fen Peng,Jie Wang,Lin Liu,Lei Meng,Jing Zhao,Xiao-Ning Han,Wen-Hui Ding
Catestatin in defense of oxidative-stress-induced apoptosis: A novel mechanism by activating the beta2 adrenergic receptor and PKB/Akt pathway in ischemic-reperfused myocardium
Peptides. 2020 Jan;123:170200.;doi: 10.1016/j.peptides.2019.170200. (IF 2.843)

194. Yong Qiao,Zhongjuan Xu,Yanzhen Yu,Shulan Hou,Junsa Geng,Tongqian Xiao,Yu Liang,Qun Dong,Yan Mei,Bin Wang,Hong Qiao,Jianwu Dai,Guangli Suo
Single cell derived spheres of umbilical cord mesenchymal stem cells enhance cell stemness properties, survival ability and therapeutic potential on liver failure
Biomaterials. 2020 Jan;227:119573.;doi: 10.1016/j.biomaterials.2019.119573. (IF 10.317)

195. Jun Li,Xuemei Yang,Fang Liu,Yaman Song,Yuanke Liu
Activated PI3K/AKT Signaling Pathway Associates with Oxidative Stress and Impaired Developmental Potential of Vitrified-Thawed Oocytes
Reprod Sci. 2020 Jan;27(1):404-410.;doi: 10.1007/s43032-019-00036-1. (IF 2.616)

196. Kailin Jiao,Jing Zhen,Maoxuan Wu,Mengying Teng,Keke Yang,Qian Zhou,Chunyan Hu,Ming Zhou,Yuan Li,Zhong Li
27-Hydroxycholesterol-induced EndMT acts via STAT3 signaling to promote breast cancer cell migration by altering the tumor microenvironment
Cancer Biol Med. 2020 Feb 15;17(1):88-100.;doi: 10.20892/j.issn.2095-3941.2019.0262. (IF 5.432)

197. Yu Wang,Hongjing Zhao,Menghao Guo,Dongxue Fei,Lina Zhang,Mingwei Xing
Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress
J Hazard Mater. 2020 Feb 5;383:121217.;doi: 10.1016/j.jhazmat.2019.121217. (IF 9.038)

198. Xiaoteng Fan,Tingting Hou,Shuai Zhang,Yongjing Guan,Jia Jia,Zaizhao Wang
The cellular responses of autophagy, apoptosis, and 5-methylcytosine level in zebrafish cells upon nutrient deprivation stress
Chemosphere. 2020 Feb;241:124989.;doi: 10.1016/j.chemosphere.2019.124989. (IF 5.778)

199. Yuan Zhang,Wei-Jian Huang,Qiu-Rui Yang,Hong-Dan Zhang,Xue-Jing Zhu,Min Zeng,Xu Zhou,Zhen-Yu Wang,Wei-Jian Li,Hong-Shu Jing,Xue-Bin Zhang,Yao-Ping Shi,Hao Hu,He-Xin Yan,Zong-Hai Li,Bo Zhai
Cryopreserved biopsy tissues of rectal cancer liver metastasis for assessment of anticancer drug response in vitro and in vivo
Oncol Rep. 2020 Feb;43(2):405-414.;doi: 10.3892/or.2019.7450. (IF 3.417)

200. Chaogang Tang,Jianying Ou,Li Kou,Jinfeng Deng,Shijian Luo
Circ_016719 plays a critical role in neuron cell apoptosis induced by I/R via targeting miR-29c/Map2k6
MOL CELL PROBE. 2020 Feb;49:101478.;doi: 10.1016/j.mcp.2019.101478. (IF 1.951)

201. Liqiang Qian,Haoyuan Su,Gang Wang,Bin Li,Genhai Shen,Quangen Gao
Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated MEK/ERK and PI3K/AKT Signaling Pathways in Gallbladder Cancer
J Cancer. 2020 Mar 4;11(11):3114-3123.;doi: 10.7150/jca.38393. (IF 3.565)

202. Denghui Zhu,Rong Huang,Pengfei Chu,Liangming Chen,Yangyu Li,Libo He,Yongming Li,Lanjie Liao,Zuoyan Zhu,Yaping Wang
Characterization and expression of galectin-3 in grass carp (Ctenopharyngodon idella)
Dev Comp Immunol. 2020 Mar;104:103567.;doi: 10.1016/j.dci.2019.103567. (IF 3.192)

203. Long Fan,Leng Li,Xuhua Yu,Ziyao Liang,Tiantian Cai,Yuanbin Chen,Yinji Xu,Tao Hu,Lei Wu,Lin Lin
Jianpiyifei II Granules Suppress Apoptosis of Bronchial Epithelial Cells in Chronic Obstructive Pulmonary Disease via Inhibition of the Reactive Oxygen Species-Endoplasmic Reticulum Stress-Ca 2+ Signa
Front Pharmacol. 2020 Apr 30;11:581.;doi: 10.3389/fphar.2020.00581. (IF 4.225)

204. Jialiang Lin,Jinru Zhuge,Xuanqi Zheng,Yuhao Wu,Zengjie Zhang,Tianzhen Xu,Zaher Meftah,Hongming Xu,Yaosen Wu,Naifeng Tian,Weiyang Gao,Yifei Zhou,Xiaolei Zhang,Xiangyang Wang
Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration via the AMPK signaling pathway
FREE RADICAL BIO MED. 2020 Apr;150:109-119.;doi: 10.1016/j.freeradbiomed.2020.02.024. (IF 6.17)

205. Chengcheng Gao,Xin Sun,Zhipan Wu,Huahua Yuan,Haote Han,Hongliang Huang,Yuhan Shu,Mengting Xu,Ruilan Gao,Shouxin Li,Jianbin Zhang,Jingkui Tian
A Novel Benzofuran Derivative Moracin N Induces Autophagy and Apoptosis Through ROS Generation in Lung Cancer
Front Pharmacol. 2020 May 12;11:391.;doi: 10.3389/fphar.2020.00391. (IF 4.225)

206. Mengxue Sun,Jie Hua,Gaoshuang Liu,Peiyun Huang,Ningsheng Liu,Xiaopu He
Myrrh induces the apoptosis and inhibits the proliferation and migration of gastric cancer cells through down-regulating cyclooxygenase-2 expression
BIOSCIENCE REP. 2020 May 29;40(5):BSR20192372.;doi: 10.1042/BSR20192372. (IF 2.942)

207. Boya Zhang,Shiyu Wan,Xinyu Peng,Mingying Zhao,Sai Li,Yuji Pu,Bin He
Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity
J Mater Chem B. 2020 May 6;8(17):3939-3948.;doi: 10.1039/d0tb00327a. (IF 5.344)

208. Hengwei Deng,Lei Hu,Jingjing Li,Wenyan Yan,Enhui Song,Mingqing Kuang,Shanshan Liu,Jianguo He,Shaoping Weng
The NF-κB family member dorsal plays a role in immune response against Gram-positive bacterial infection in mud crab (Scylla paramamosain)
Dev Comp Immunol. 2020 May;106:103581.;doi: 10.1016/j.dci.2019.103581. (IF 3.192)

209. Zhihui Liu,Chao Wu,Xinliang Zou,Weiming Shen,Jiacai Yang,Xiaorong Zhang,Xiaohong Hu,Haidong Wang,Yi Liao,Tao Jing
Exosomes derived from mesenchymal stem cells inhibit neointimal hyperplasia by activating the Erk1/2 signalling pathway in rats
Stem Cell Res Ther. 2020 Jun 8;11(1):220.;doi: 10.1186/s13287-020-01676-w. (IF 5.116)

210. Zhijun Li,Yifei Yu,Juanjuan Kang,Yangyang Zheng,Jinying Xu,Kan Xu,Kun Hou,Yi Hou,Guangfan Chi
MicroRNA-124 Overexpression in Schwann Cells Promotes Schwann Cell-Astrocyte Integration and Inhibits Glial Scar Formation Ability
Front Cell Neurosci. 2020 Jul 2;14:144.;doi: 10.3389/fncel.2020.00144. (IF 3.921)

211. Bo Zhang,Xinhai Mo,Fei Yu,Yuqin Ma,Fei Yan
Ultrasound monitoring of magnet-guided delivery of mesenchymal stem cells labeled with magnetic lipid-polymer hybrid nanobubbles
BIOMATER SCI-UK. 2020 Jul 7;8(13):3628-3639.;doi: 10.1039/d0bm00473a. (IF 6.183)

212. Yingjie Zhang,Lishu Zhou,Zhaoqiang Zhang,Fei Ren,Liangjiao Chen,Zedong Lan
miR‑10a‑5p inhibits osteogenic differentiation of bone marrow‑derived mesenchymal stem cells
Mol Med Rep. 2020 Jul;22(1):135-144.;doi: 10.3892/mmr.2020.11110. (IF 2.1)

213. Ruofeng Yin,Jiajia Jiang,Huimin Deng,Zhaobin Wang,Rui Gu,Fei Wang
miR-140-3p aggregates osteoporosis by targeting PTEN and activating PTEN/PI3K/AKT signaling pathway
Hum Cell. 2020 Jul;33(3):569-581.;doi: 10.1007/s13577-020-00352-8. (IF 3.463)

214. Chen Zhao,Ye Wang,Zhonglan Su,Wenyuan Pu,Mengyuan Niu,Shiyu Song,Lulu Wei,Yibing Ding,Lizhi Xu,Man Tian,Hongwei Wang
Respiratory exposure to PM2.5 soluble extract disrupts mucosal barrier function and promotes the development of experimental asthma
Sci Total Environ. 2020 Aug 15;730:139145.;doi: 10.1016/j.scitotenv.2020.139145. (IF 6.551)

215. Fidelis Chibhabha,Yaqi Yang,Kuang Ying,Fujie Jia,Qin Zhang,Shahid Ullah,Zibin Liang,Muke Xie,Feng Li
Non-invasive optical imaging of retinal Aβ plaques using curcumin loaded polymeric micelles in APP swe/PS1 ΔE9 transgenic mice for the diagnosis of Alzheimer’s disease
J Mater Chem B. 2020 Aug 26;8(33):7438-7452.;doi: 10.1039/d0tb01101k. (IF 5.344)

216. Shihai Liu,Jing Qiu,Guifang He,Chao Geng,Weitai He,Changchang Liu,Duo Cai,Huazheng Pan,Qingwu Tian
Dermatopontin inhibits WNT signaling pathway via CXXC finger protein 4 in hepatocellular carcinoma
J Cancer. 2020 Aug 29;11(21):6288-6298.;doi: 10.7150/jca.47157. (IF 3.565)

217. Liu De,Tang Yuan,Zheng Yong
ST1926 inhibits glioma progression through regulating mitochondrial complex II
Biomed Pharmacother. 2020 Aug;128:110291.;doi: 10.1016/j.biopha.2020.110291. (IF 4.545)

218. Hai-Zhen Zhu,Chun-Ju Fang,Yi Guo,Qi Zhang,Li-Min Huang,Dong Qiu,Guang-Peng Chen,Xiu-Feng Pang,Jian-Jun Hu,Jian-Guo Sun,Zheng-Tang Chen
Detection of miR-155-5p and imaging lung cancer for early diagnosis: in vitro and in vivo study
J CANCER RES CLIN. 2020 Aug;146(8):1941-1951.;doi: 10.1007/s00432-020-03246-2. (IF 3.656)

219. Shuo Wu,Hui-Qiang Wang,Ting-Ting Guo,Yu-Huan Li
Luteolin inhibits CVB3 replication through inhibiting inflammation
J Asian Nat Prod Res. 2020 Aug;22(8):762-773.;doi: 10.1080/10286020.2019.1642329. (IF 1.345)

220. Ying Long,Xianjin Wu,Zhen Li,Jialong Fan,Xing Hu,Bin Liu
PEGylated WS 2 nanodrug system with erythrocyte membrane coating for chemo/photothermal therapy of cervical cancer
BIOMATER SCI-UK. 2020 Sep 21;8(18):5088-5105.;doi: 10.1039/d0bm00972e. (IF 6.183)

221. Jiajia Hao,Yafen Song,Bin Tian,Changxi Qi,Liping Li,Lumei Wang,Yuxiao Xing,Xiaona Zhao,Jianzhu Liu
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells
ECOTOX ENVIRON SAFE. 2020 Oct 1;202:110901.;doi: 10.1016/j.ecoenv.2020.110901. (IF 4.872)

222. Xiaodan Qu,Peipei Guan,Li Han,Zhanyou Wang,Xueshi Huang
Levistolide A Attenuates Alzheimer’s Pathology Through Activation of the PPARγ Pathway
Neurotherapeutics. 2020 Oct 9.;doi: 10.1007/s13311-020-00943-1. (IF 6.035)

223. Dejun Xu,Huanshan He,Dingbang Liu,Guoxia Geng,Qingwang Li
A novel role of SIRT2 in regulating gap junction communications via connexin-43 in bovine cumulus-oocyte complexes
J Cell Physiol. 2020 Oct;235(10):7332-7343.;doi: 10.1002/jcp.29634. (IF 5.546)

224. Yang Liu,Peng Qin,Rong Wu,Lianfang Du,Fan Li
ERas regulates cell proliferation and epithelial-mesenchymal transition by affecting Erk/Akt signaling pathway in pancreatic cancer
Hum Cell. 2020 Oct;33(4):1186-1196.;doi: 10.1007/s13577-020-00401-2. (IF 3.463)

225. Yangbiao He,Xujun Lang,Dong Cheng,Ting Zhang,Zhihao Yang,Rongbing Xiong
miR‑30a‑5p inhibits hypoxia/reoxygenation‑induced oxidative stress and apoptosis in HK‑2 renal tubular epithelial cells by targeting glutamate dehydrogenase 1 (GLUD1)
Oncol Rep. 2020 Oct;44(4):1539-1549.;doi: 10.3892/or.2020.7718. (IF 3.417)

226. Wenjin Wang,Jingfang Feng,Hongying Zhou,Qi Li
Circ_0123996 promotes cell proliferation and fibrosisin mouse mesangial cells through sponging miR-149-5p and inducing Bach1 expression
Gene. 2020 Nov 30;761:144971.;doi: 10.1016/j.gene.2020.144971. (IF 2.984)

227. Yiqun Ji,Jialu Yao,Yang He
Extracellular ubiquitin protects cardiomyocytes during ischemia/hypoxia by inhibiting mitochondrial apoptosis pathway through CXCR4
Biomed Pharmacother. 2020 Nov;131:110787.;doi: 10.1016/j.biopha.2020.110787. (IF 4.545)

228. Yi Shen,Xiaoyi Zhang,Chenguang Li,Xiang Wang,Yong Ye,Jie Yuan,Hui Gong,Yunzeng Zou,Junbo Ge
Pressure overload promotes cystatin C secretion of cardiomyocytes to regulate the MAPK signaling pathway and mediate cardiac hypertrophy
Ann Transl Med. 2020 Nov;8(22):1514.;doi: 10.21037/atm-20-7041. (IF 3.297)

229. Nan Wang,Yanping Feng,Jinye Xie,Hui Han,Qian Dong,Weijia Wang
Long Non-Coding RNA ZNF667-AS1 Knockdown Curbs Liver Metastasis in Acute Myeloid Leukemia by Regulating the microRNA-206/AKAP13 Axis
Cancer Manag Res. 2020 Dec 23;12:13285-13300.;doi: 10.2147/CMAR.S269258. (IF 2.886)

230. Ya Li,Qiuju Han,Huajun Zhao,Quanjuan Guo,Jian Zhang
Napabucasin Reduces Cancer Stem Cell Characteristics in Hepatocellular Carcinoma
Front Pharmacol. 2020 Dec 3;11:597520.;doi: 10.3389/fphar.2020.597520. (IF 4.225)

231. Yu Gu,Songtao Lai,Yang Dong,Hao Fu,Liwei Song,Tianxiang Chen,Yourong Duan,Zhen Zhang
AZD9291 Resistance Reversal Activity of a pH-Sensitive Nanocarrier Dual-Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC
Adv Sci (Weinh). 2020 Dec 4;8(2):2002922.;doi: 10.1002/advs.202002922.

232. Lin Yang,Delin Kong,Mei He,Jiawei Gong,Yuzhe Nie,Sheng Tai,Chun-Bo Teng
MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma
BBA-MOL CELL RES. 2020 Dec;1867(12):118826.;doi: 10.1016/j.bbamcr.2020.118826. (IF 4.105)

233. Xiangwa Chen,Tao Deng,Tingting Huo,Faqin Dong,Jianjun Deng
MiR-140-5p/TLR4 /NF-κB signaling pathway: Crucial role in inflammatory response in 16HBE cells induced by dust fall PM 2.5
ECOTOX ENVIRON SAFE. 2021 Jan 15;208:111414.;doi: 10.1016/j.ecoenv.2020.111414. (IF 4.872)

234. Guanting Li,Xianwei Wu,Peng Sun,Zhiyang Zhang,Enxian Shao,Jianping Mao,Hua Cao,Hongliang Huang
Dithiolation indolizine exerts viability suppression effects on A549 cells via triggering intrinsic apoptotic pathways and inducing G2/M phase arrest
Biomed Pharmacother. 2021 Jan;133:110961.;doi: 10.1016/j.biopha.2020.110961. (IF 4.545)

235. Yanjiao Hou,Hengmin Jia,Yanhong Cao,Shuang Zhang,Xiaolei Zhang,Pingping Wei,Jun Xie,Wenqian Dong,Baolong Wang
LncRNA EPIC1 promotes tumor angiogenesis via activating the Ang2/Tie2 axis in non-small cell lung cancer
Life Sci. 2021 Feb 15;267:118933.;doi: 10.1016/j.lfs.2020.118933. (IF 3.647)

236. Jing Luo,Weian Zhao,Yi Gan,Bo Pan,Lingjuan Liu,Zhenguo Liu,Jie Tian
Cardiac Troponin I R193H Mutation Is Associated with Mitochondrial Damage in Cardiomyocytes
DNA Cell Biol. 2021 Feb;40(2):184-191.;doi: 10.1089/dna.2020.5828. (IF 3.191)

237. Jin Hou,Ling Zhao,Huaqiao Tang,Xiaoli He,Gang Ye,Fei Shi,Min Kang,Helin Chen,Yinglun Li
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway
Biol Trace Elem Res. 2021 Mar;199(3):1062-1073.;doi: 10.1007/s12011-020-02212-w. (IF 2.639)

238. Chong Yuan,Meng-Heng Wang,Fei Wang,Peng-Yu Chen,Xin-Ge Ke,Bing Yu,Yan-Fang Yang,Peng-Tao You,He-Zhen Wu
Network pharmacology and molecular docking reveal the mechanism of Scopoletin against non-small cell lung cancer
Life Sci. 2021 Apr 1;270:119105.;doi: 10.1016/j.lfs.2021.119105. (IF 3.647)

239. Lin Chen,Jinying Xu,Shuang Lv,Yan Zhao,Dongjie Sun,Yangyang Zheng,Xianglan Li,Lihong Zhang,Guangfan Chi,Yulin Li
Overexpression of long non-coding RNA AP001505.9 inhibits human hyaline chondrocyte dedifferentiation
AGING-US. 2021 Apr 4;13(8):11433-11454.;doi: 10.18632/aging.202833. (IF 4.831)

240. Shuo Zhang,Xiaona Zhao,Jiajia Hao,Yiran Zhu,Yue Wang,Lumei Wang,Shuhua Guo,Hui Yi,Yongxia Liu,Jianzhu Liu
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells
J Hazard Mater. 2021 May 15;410:124607.;doi: 10.1016/j.jhazmat.2020.124607. (IF 9.038)

241. Xiao-Feng Yue,Chong-Xing Shen,Jian-Wu Wang,Lin-Yong Dai,Qiang Fang,Lei Long,Yi Zhi,Xue-Ru Li,Ya-Wei Wang,Gu-Fang Shen,Zu-Juan Liu,Chun-Meng Shi,Wei-Bing Li
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection
Asian J Androl. May-Jun 2021;23(3):249-258.;doi: 10.4103/aja.aja_69_20. (IF 2.448)

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