Hoechst 33342染色液
产品编号: C1026
产品包装:50ml
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Hoechst 33342染色液(C1026)
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价格: ¥ 341.00
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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| C1025 | Hoechst 33342染色液 | 10ml | 101.00元 |
| C1026 | Hoechst 33342染色液 | 50ml | 341.00元 |
Hoechst 33342，也称bisBenzimide H 33342或HOE 33342。分子式为C27H28N6O·3HCl·3H2O，分子量为615.99，CAS Number 23491-52-3。
Hoechst 33342是一种可以穿透细胞膜的蓝色荧光染料，对细胞的毒性较低。
Hoechst 33342染色常用于细胞凋亡检测，染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33342也常用于普通的细胞核染色，或常规的DNA染色。
Hoechst 33342的最大激发波长为346nm，最大发射波长为460nm；Hoechst 33342和双链DNA结合后，最大激发波长为350nm，最大发射波长为461nm。
本Hoechst 33342染色液可直接用于固定细胞或组织的细胞核染色，也可直接用于活细胞或组织的细胞核染色。
包装清单：
| 产品编号 | 产品名称 | 包装 |
| C1026 | Hoechst 33342染色液 | 50ml |
| — | 说明书 | 1份 |
保存条件：
-20℃避光保存，一年有效。
注意事项：
本Hoechst 33342 染色液的浓度经过碧云天的优化，确保可以满足各种常规染色的需要。如需使用特定浓度的Hoechst 33342，请选购碧云天的Hoechst 33342(C1022)。如需染色活细胞或培养的组织，请选购碧云天的Hoechst 33342活细胞染色液(100X) (C1027、C1028或C1029)，效果更佳。
荧光染料都存在淬灭的问题，建议染色后尽量当天完成检测。活细胞或组织染色后宜立即观察。
为减缓荧光淬灭可以使用抗荧光淬灭封片液。抗荧光淬灭封片液(P0126)可以向碧云天订购。
Hoechst 33342对人体有害，请注意适当防护。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用说明：
1. 对于固定的细胞或组织：
a.对于细胞或组织样品，固定后，适当洗涤去除固定剂。随后如果需要进行免疫荧光染色，则先进行免疫荧光染色，染色完毕后再按后续步骤进行Hoechst 33342染色。如果不需要进行其它染色，则直接进行后续的Hoechst 33342染色。
b.对于贴壁细胞或组织切片，加入少量Hoechst 33342染色液，覆盖住样品即可。对于悬浮细胞，至少加入待染色样品体积3倍的染色液，混匀。室温放置3-5分钟。
c. 吸除Hoechst 33342染色液，用TBST、PBS或生理盐水洗涤2-3次，每次3-5分钟。
d.直接在荧光显微镜下观察或封片后荧光显微镜下观察。细胞发生凋亡时，会看到凋亡细胞的细胞核呈致密浓染，或呈碎块状致密浓染。
2. 对于活细胞或培养的组织：
a. 加入适当量Hoechst 33342染色液，必须充分覆盖住待染色的样品，通常对于六孔板一个孔需加入1ml染色液，对于96孔板一个孔需加入100微升染色液。
b. 在适宜于细胞培养的温度培养20-30分钟。弃染色液，用PBS或培养液洗涤2-3次即可进行荧光检测。细胞发生凋亡时，在荧光显微镜下观察会看到凋亡细胞的细胞核呈致密浓染，或呈碎块状致密浓染。
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| C1028 | Hoechst 33342活细胞染色液(100X) | 0.5ml |
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相关产品请点击如下按钮：
荧光染色
细胞凋亡
细胞凋亡荧光探针
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PLoS One . 2015 Jul 13;10(7):e0132829. (IF 2.74)
75. Hu XL, Guo LP, Song Q, Zhang Q, Chen Y, Wang J, Meng WH, Zhao QC.
Kukoamine B, an amide alkaloid, protects against NMDA-induced neurotoxicity and potential mechanisms in vitro.
Neurochem Int . 2015 Aug;87:66-76. (IF 3.881)
76. Wang DF, Yang HJ, Gu JQ, Cao YL, Meng X, Wang XL, Lin YC, Gao M.
Suppression of phosphatase and tensin homolog protects insulin-resistant cells from apoptosis.
Mol Med Rep . 2015 Aug;12(2):2695-700. (IF 2.1)
77. Jiao Y, Ma S, Li J, Shan L, Wang Y, Tian M, Yang Y, Sun J, Ban J, Chen J.
N-Acetyl Cysteine (NAC)-Directed Detoxification of Methacryloxylethyl Cetyl Ammonium Chloride (DMAE-CB).
PLoS One . 2015 Aug 14;10(8):e0135815. (IF 2.74)
78. Chen H, Liao K, Cui-Zhao L, Qiang-Wen F, Feng-Zeng X, Ping-Wu F, Liang-Guo S, Juan-Chen Y.
Cigarette smoke extract induces apoptosis of rat alveolar Type II cells via the PLTP/TGF-β1/Smad2 pathway.
Int Immunopharmacol . 2015 Sep;28(1):707-14. (IF 3.943)
79. Chen JJ, Hong G, Gao LJ, Liu TJ, Cao WJ.
In vitro and in vivo antitumor activity of a novel porphyrin-based photosensitizer for photodynamic therapy.
J CANCER RES CLIN . 2015 Sep;141(9):1553-61. (IF 3.656)
80. Ma NT, Zhou R, Chang RY, Hao YJ, Ma L, Jin SJ, Du J, Zheng J, Zhao CJ, Niu Y, Sun T, Li W, Koike K, Yu JQ, Li YX.
Protective effects of aloperine on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion.
J NAT MED-TOKYO . 2015 Oct;69(4):575-83. (IF 2.055)
81. Cai XY, Xia Y, Yang SH, Liu XZ, Shao ZW, Liu YL, Yang W, Xiong LM.
Ropivacaine- and bupivacaine-induced death of rabbit annulus fibrosus cells in vitro: involvement of the mitochondrial apoptotic pathway.
OSTEOARTHR CARTILAGE . 2015 Oct;23(10):1763-75. (IF 4.793)
82. Yan F, Wang X, Shao L, Ge M, Hu X.
Analysis of UHRF1 expression in human ovarian cancer tissues and its regulation in cancer cell growth.
TUMOR BIOL . 2015 Nov;36(11):8887-93. (IF 3.65)
83. Zhao Q, Peng Y, Huang K, Lei Y, Liu HL, Tao YY, Liu CH.
Salvianolate Protects Hepatocytes from Oxidative Stress by Attenuating Mitochondrial Injury.
EVID-BASED COMPL ALT . 2016;2016:5408705. (IF 1.813)
84. Zhen N, Yang Q, Wu Q, Zhu X, Wang Y, Sun F, Mei W, Yu Y.
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
CANCER CHEMOTH PHARM . 2016 Jan;77(1):169-80. (IF 2.967)
85. Zhang Q, Fan K, Wang P, Yu J, Liu R, Qi H, Sun H, Cao Y.
Carvacrol induces the apoptosis of pulmonary artery smooth muscle cells under hypoxia.
Eur J Pharmacol . 2016 Jan;770(5):134-6. (IF 3.263)
86. Yu X, Wang J, Liu J, Shen S, Cao Z, Pan J, Zhou S, Pang Z, Geng D, Zhang J.
A multimodal Pepstatin A peptide-based nanoagent for the molecular imaging of P-glycoprotein in the brains of epilepsy rats.
Biomaterials . 2016 Jan;76:173-86. (IF 10.317)
87. Zhen N, Yang Q, Wu Q, Zhu X, Wang Y, Sun F, Mei W, Yu Y .
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agentinhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
CANCER CHEMOTH PHARM . 2016 Jan;77(1):169-80. (IF 2.967)
88. He X, Yu H, Bao X, Cao H, Yin Q, Zhang Z, Li Y.
pH-Responsive Wormlike Micelles with Sequential Metastasis Targeting Inhibit Lung Metastasis of Breast Cancer.
Adv Healthc Mater . 2016 Feb 18;5(4):439-48. (IF 7.367)
89. Shi M, Ren X, Wang X, Wang H, Liu G, Yuan X, Zheng S, Yu L, Pan S, Song G, Guo Q, Li L, Zhang X, Zhang Z, Ding H, Jiang G.
A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells.
Int J Oncol . 2016 Feb;48(2):734-46. (IF 3.899)
90. Dan J, Sun X, Li W, Zhang Y, Li X, Xu H, Li Z, Tian Z, Guo S, Yao J, Gao W, Tian Y.
5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells.
Ultrasound Med Biol .2016 Feb;5(4):439–48. (IF 2.514)
91. Wang W, Luo J, Liang Y, Li X .
Echinacoside suppresses pancreatic adenocarcinoma cell growth by inducing apoptosis via themitogen-activated protein kinase pathway.
Mol Med Rep . 2016 Mar;13(3):2613-8. (IF 2.1)
92. Zhang LJ, Yan YJ, Liao PY, Margetic D, Wang L, Chen ZL.
Synthesis and antitumor activity evaluation of a novel porphyrin derivative for photodynamic therapy in vitro and in vivo.
TUMOR BIOL .2016 May;37(5):6923–33. (IF 3.65)
93. Wang Y, Tu L, Li Y, Chen D, Wang S .
Notoginsenoside R1 Protects against Neonatal Cerebral Hypoxic-Ischemic Injury through EstrogenReceptor-Dependent Activation of Endoplasmic Reticulum Stress Pathways.
J Pharmacol Exp Ther . 2016 Jun;357(3):591-605. (IF 3.561)
94. Yang X, Lv Y, Huang K, Luo Y, Xu W .
Zinc inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in human hepatocytes (HepG2 cells).
Food Chem Toxicol . 2016 Jun;92:17-25. (IF 4.679)
95. Gu LL, Zhang XY, Xing WM, Xu JD, Lu H .
Andrographolide-induced apoptosis in human renal tubular epithelial cells: Roles of endoplasmicreticulum stress and inflammatory response.
ENVIRON TOXICOL CHEM . 2016 Jul;45:257-64. (IF 3.152)
96. Zhang XH, Zhang LJ, Sun JJ, Yan YJ, Zhang LX, Chen N, Chen ZL .
Photodynamic efficiency of a chlorophyll-a derivative in vitro and in vivo.
Biomed Pharmacother . 2016 Jul;81:265-72. (IF 4.545)
97. Sun M, Zhou C, Zeng H, Yin F, Wang Z, Yao J, Hua Y, Cai Z.
Benzochloroporphyrin derivative photosensitizer-mediated photodynamic therapy for Ewing sarcoma.
J PHOTOCH PHOTOBIO B . 2016 Jul;160:178-84. (IF 4.383)
98. Zhang LJ, Zhang XH, Liao PY, Sun JJ, Wang L, Yan YJ, Chen ZL .
Antitumor activity evaluation of meso-tetra (pyrrolidine substituted) pentylporphin-mediatedphotodynamic therapy in vitro and in vivo.
J PHOTOCH PHOTOBIO B . 2016 Oct;163:224-31. (IF 4.383)
99. Zhang C, Yu L, Zhou Y, Zhao Q, Liu SQ.
Chitosan oligosaccharides inhibit IL-1β-induced chondrocyte apoptosis via the P38 MAPK signalingpathway.
GLYCOCONJUGATE J . 2016 Oct;33(5):735-44. (IF 2.197)
100. Wang Y, Liu Q, Xu Y, Zhang Y, Lv Y, Tan Y, Jiang N, Cao G, Ma X, Wang J, Cao Z, Yu B, Kou J.
Ginsenoside Rg1 Protects against Oxidative Stress-induced Neuronal Apoptosis through Myosin IIA-actin Related Cytoskeletal Reorganization.
Int J Biol Sci . 2016 Oct 25;12(11):1341-1356. (IF 4.858)
101. Liu Y, Li F, Gao F, Xing L, Qin P, Liang X, Zhang J, Qiao X, Lin L, Zhao Q, Du L .
Periostin promotes the chemotherapy resistance to gemcitabine in pancreatic cancer.
TUMOR BIOL . 2016 Nov;37(11):15283-15291. (IF 3.65)
102. Bai JA, Jie H, Wei S, Wang S, Guo H, Tang Q .
GART mediates the renewal of intestinal epithelial barrier via p38/p53/PUMA cascade in colitis.
Apoptosis . 2016 Dec;21(12):1386-1397. (IF 4.543)
103. Fan Y, Liu J, Liu D, Zhou Z, Bao Y, Wang J, Zhao Q, Xu Y.
NSCA-1-a novel N-substituted coumalamide derivative-increases Adriamycin sensitivity inHepG2/adriamycin cells through modulating Akt/GSK-3β signaling and p53-dependant apoptotic pathway.
ENVIRON TOXICOL CHEM . 2017 Jan;49:1-7. (IF 3.152)
104. Hu Y, Xiong LL, Zhang P, Wang TH .
Microarray expression profiles of genes in lung tissues of rats subjected to focal cerebral ischemia-induced lung injury following bone marrow-derived mesenchymal stem cell transplantation.
Int J Mol Med . 2017 Jan;39(1):57-70. (IF 3.098)
105. Zhang Y, Wu JY, Weng LH, Li XX, Yu LJ, Xu Y.
Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy.
Neurosci Lett . 2017 Jan 18;638:60-68. (IF 2.274)
106. You F, Li Q, Jin G, Zheng Y, Chen J, Yang H.
Genistein protects against Aβ25-35 induced apoptosis of PC12cells through JNK signaling and modulation of Bcl-2 family messengers.
BMC Neurosci . 2017 Jan 12;18(1):12. (IF 2.811)
107. Wang Z, Liao K, Zuo W, Liu X, Qiu Z, Gong Z, Liu C, Zeng Q, Qian Y, Jiang L, Bu Y, Hong S, Hu G.
Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53-ROS-Mitochondrial Pathway.
Oncol Res . 2017 Jan 2;25(1):123-136. (IF 4.949)
108. Hu Y, Xiong LL, Zhang P, Wang TH.
Microarray expression profiles of genes in lung tissues of rats subjected to focal cerebralischemia-induced lung injury following bone marrow-derived mesenchymal stem cell transplantation.
Int J Mol Med . 2017 Jan;39(1):57-70. (IF 3.098)
109. Fan Y, Liu J, Liu D, Zhou Z, Bao Y, Wang J, Zhao Q, Xu Y.
NSCA-1-a novel N-substituted coumalamide derivative-increases Adriamycin sensitivity in HepG2/adriamycin cells through modulating Akt/GSK-3β signaling and p53-dependant apoptotic pathway.
ENVIRON TOXICOL CHEM . 2017 Jan;49:1-7. (IF 3.152)
110. Chang S, Ruan WC, Xu YZ, Wang YJ, Pang J, Zhang LY, Liao H, Pang T.
The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway.
Acta Pharmacol Sin . 2017 Jan;38(1):29-40. (IF 5.064)
111. Wang Y1, Qiu Y1, Yin S1, Zhang L1, Shi K1, Gao H1, Zhang Z1, He Q1.
A functional nanocarrier that copenetrates extracellular matrix and multiple layers of tumor cells for sequential and deep tumor autophagy inhibitor and chemotherapeutic delivery.
Autophagy . 2017 Feb;13(2):359-370. (IF 9.77)
112. Wen Y, He W, Jiang M, Zeng M, Cai L.
Deriving cells expressing markers of female germ cells from premature ovarian failure patient-specific induced pluripotent stem cells.
Regen Med . 2017 Mar;12(2):143-152. (IF 2.598)
113. Zhai Y1, Li Y2, Wang Y3, Cui J2, Feng K4, Kong X2, Chen L5.
Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance boneformation of osteoblasts and decrease bone resorption of osteoclasts.
Eur J Pharmacol . 2017 Apr 15;801:62-71. (IF 3.263)
114. Wu J, Yang X, Lu H, Liu L, Xu B, Zheng S, Yu B, Jie K, Wan F.
Inhibitory effect and mechanism of exogenous mammalian sterile 20-like kinase 1 on the growth of human colorectal cancer.
Oncol Lett . 2017 Apr;13(4):2656-2664. (IF 2.311)
115. Guo Y, Song Z, Zhou M, Yang Y, Zhao Y, Liu B, Zhang X.
Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway.
ONCOTARGET . 2017 Jun 7;8(32):53276-53287. (IF 5.168)
116. Sun L, Li Y, Jia X, Wang Q, Li Y, Hu M, Tian L, Yang J, Xing W, Zhang W, Wang J, Xu H, Wang L, Zhang D, Ren H.
Neuroprotection byIFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation.
ONCOTARGET . 2017 Jun 20;8(25):40065-40078. (IF 5.168)
117. Xiong LL, Liu F, Lu BT, Zhao WL, Dong XJ, Liu J, Zhang RP, Zhang P, Wang TH.
Bone Marrow Mesenchymal Stem-Cell Transplantation Promotes Functional ImprovementAssociated with CNTF-STAT3 Activation after Hemi-Sectioned Spinal Cord Injury in Tree Shrews.
Front Cell Neurosci . 2017 Jun 28;11:172. (IF 3.921)
118. Wu X, Gao H, Sun W, Yu J, Hu H, Xu Q, Chen X.
Nepetoidin B,a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways.
Phytother Res . 2017 Jul;31(7):1072-1077. (IF 4.087)
119. Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J.
Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Srcdependent NADPH oxidase/ROS pathway.
Exp Cell Res . 2017 Aug 15;357(2):243-251. (IF 3.383)
120. Liu JC, Lai FN, Li L, Sun XF, Cheng SF, Ge W, Wang YF, Li L, Zhang XF, De Felici M, Dyce PW, Shen W.
Di (2-ethylhexyl) phthalate exposure impairs meiotic progression and DNA damage repair in fetalmouse oocytes in vitro.
Cell Death Dis . 2017 Aug 3;8(8):e2966. (IF 6.304)
121. Liu XY, Zhang LJ, Chen Z, Liu LB.
The PTEN inhibitor bpV(pic) promotes neuroprotection against amyloid β-peptide(25-35)-inducedoxidative stress and neurotoxicity.
Neurol Res . 2017 Aug;39(8):758-765. (IF 2.401)
122. Shan ZL, Zhong L, Xiao CL, Gan LG, Xu T, Song H, Yang R, Li L, Liu BZ.
Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells through modulation of MAPKs and c Myc.
Mol Med Rep . 2017 Sep;16(3):3055-3060. (IF 2.1)
123. Hao J, Yang Z, Wang L, Zhang Y, Shu Y, Jiang L, Hu Y, Lv W, Dong P, Liu Y.
Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and inducesapoptosis via PI3K/AKT pathway.
Int J Oncol . 2017 Sep;51(3):823-831. (IF 3.899)
124. Liu X, Qiu Z, Wang Z, Zuo W, Gong Z, Liu C, Zeng Q, Qian Y, Jiang L, Li Y, Bu Y, Hu G.
NFBD1/MDC1 participates inthe regulation of proliferation and apoptosis in human laryngealsquamous cell carcinoma.
Clin Transl Oncol . 2017 Sep 18. (IF 2.737)
125. Ying C, Xiao BD, Qin Y, Wang BR, Liu XY, Wang RW, Fang L, Yan H, Zhou XM, Wang YG.
GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostatecancer stem-like cells in vitro and in vivo.
Acta Pharmacol Sin . 2017 Sep 7. (IF 5.064)
126. Liang J, Wang WF, Xie S, Zhang XL, Qi WF, Zhou XP, Hu JX, Shi Q, Yu RT.
β-transducin repeat-containing E3 ubiquitin protein ligase inhibits migration, invasion and proliferation of glioma cells.
Oncol Lett . 2017 Sep;14(3):3131-3135. (IF 2.311)
127. Geng YD, Zhang C, Lei JL, Yu P, Xia YZ, Zhang H, Yang L, Kong LY.
Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
Biochem Pharmacol . 2017 Oct 15;142:71-86. (IF 4.96)
128. Chen GH, Xu CS, Zhang J, Li Q, Cui HH, Li XD, Chang LP, Tang RJ, Xu JY, Tian XQ, Huang PS, Xu J, Jin C, Yang YJ.
Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1.
Front Pharmacol . 2017 Oct 30;8:775. (IF 4.225)
129. Liu W, Wang X, Liu Z, Wang Y, Yin B, Yu P, Duan X, Liao Z, Chen Y, Liu C, Li X, Dai Y, Tao Z.
SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.
BRIT J CANCER . 2017 Oct 10;117(8):1139-1153. (IF 5.791)
130. Li Y, Sun Y, Cao T, Su Q, Li Z, Huang M, Ouyang R, Chang H, Zhang S, Miao Y.
A cation-exchange controlled core-shell MnS@Bi2S3 theranostic platform for multimodal imaging guided radiation therapy with hyperthermia boost.
Nanoscale . 2017 Oct 5;9(38):14364-14375. (IF 6.895)
131. Qian L, Li X, Ye P, Wang G, Dai W, Liu Y, Gao Q, Shen G.
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKTpathway.
Cytotechnology . 2017 Nov 23. (IF 1.777)
132. Zhao C, Yao X, Chen X, Wu W, Xi F, Yang G, Yu T.
Knockdown of ubiquitin D inhibits adipogenesis duringthe differentiation of porcineintramuscular and subcutaneous preadipocytes.
CELL PROLIFERAT . 2017 Nov 23. (IF 5.753)
133. Yang LL1, Zhao Y1, Luo SM1, Ma JY1, Ge ZJ1, Shen W1, Yin S2.
Toxic Effects and Possible Mechanisms of HydrogenSulfide and/or Ammonia on Porcine OocyteMaturation in vitro.
Toxicol Lett . 2017 Dec 29. pii: S0378-4274(17)31529-1. (IF 3.569)
134. Xiao B, Qin Y, Ying C, Ma B, Wang B, Long F, Wang R, Fang L, Wang Y.
Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model.
Mol Med Rep . 2017 Dec;16(6):9375-9382. (IF 2.1)
135. Li X, Yan X, Wang Y, Wang J, Zhou F, Wang H, Xie W, Kong H.
NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells.
Exp Cell Res . 2017 Dec 16. pii: S0014-4827(17)30668-7. (IF 3.383)
136. Xu Z, Zheng M, Zhang L, Zhang X, Zhang Y, Cui X, Gong X, Xi R, Bai R.
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BMC Vet Res . 2017 Dec 28;13(1):399. (IF 1.835)
137. Liu W,Meng Q,Sun Y,Wang C,Huo X,Liu Z,Sun P,Sun H,Ma X,Liu K
Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells.
CELL PHYSIOL BIOCHEM . 2018;51(4):1616-1631. (IF 5.5)
138. Sun J,Guo Y,Zhang Q,Bu S,Li B,Wang Q,Lai D
Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes.
Cell Cycle . 2018;17(13):1591-1601. (IF 3.699)
139. Wang Y,Qin Y,Guo T,Tang C,Liu L,Gao D
High Concentration of Glial Cell Line-Derived Neurotrophic Factor Protects Primary Astrocytes from Apoptosis.
DEV NEUROSCI-BASEL . 2018;40(2):134-144. (IF 3.041)
140. Qian L,Li X,Ye P,Wang G,Dai W,Liu Y,Gao Q,Shen G
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
Cytotechnology . 2018 Feb;70(1):83-94. (IF 1.777)
141. Miao X,Gu Z,Liu Y,Jin M,Lu Y,Gong Y,Li L,Li C
The glucagon-like peptide-1 analogue liraglutide promotes autophagy through the modulation of 5′-AMP-activated protein kinase in INS-1 β-cells under high glucose conditions.
Peptides . 2018 Feb;100:127-139. (IF 2.843)
142. Ouyang G,Xiong L,Liu Z,Lam B,Bui B,Ma L,Chen X,Zhou P,Wang K,Zhang Z,Huang H,Miao X,Chen W,Wen Y
Inhibition of autophagy potentiates the apoptosis-inducing effects of photodynamic therapy on human colon cancer cells.
PHOTODIAGN PHOTODYN . 2018 Mar;21:396-403. (IF 2.894)
143. Ying C,Xiao BD,Qin Y,Wang BR,Liu XY,Wang RW,Fang L,Yan H,Zhou XM,Wang YG
GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostate cancer stem-like cells in vitro and in vivo.
Acta Pharmacol Sin . 2018 Mar;39(3):405-414. (IF 5.064)
144. Sun Y, Wang C, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Peng J, Liu K.
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+-mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
J Cell Physiol . 2018 Apr;233(4):3066-3079. (IF 5.546)
145. Sun Y,Wang C,Meng Q,Liu Z,Huo X,Sun P,Sun H,Ma X,Peng J,Liu K
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
J Cell Physiol . 2018 Apr;233(4):3066-3079. (IF 5.546)
146. Hu YP,Wu ZB,Jiang L,Jin YP,Li HF,Zhang YJ,Ma Q,Ye YY,Wang Z,Liu YC,Chen HZ,Liu YB
STYK1 promotes cancer cell proliferation and malignant transformation by activating PI3K-AKT pathway in gallbladder carcinoma.
INT J BIOCHEM CELL B . 2018 Apr;97:16-27. (IF 3.673)
147. Liu X,Qiu Z,Wang Z,Zuo W,Gong Z,Liu C,Zeng Q,Qian Y,Jiang L,Li Y,Bu Y,Hu G
NFBD1/MDC1 participates in the regulation of proliferation and apoptosis in human laryngeal squamous cell carcinoma.
Clin Transl Oncol . 2018 Apr;20(4):534-541. (IF 2.737)
148. Zhao C,Yao X,Chen X,Wu W,Xi F,Yang G,Yu T
Knockdown of ubiquitin D inhibits adipogenesis during the differentiation of porcine intramuscular and subcutaneous preadipocytes.
CELL PROLIFERAT . 2018 Apr;51(2):e12401. (IF 5.753)
149. Wang S,Cheng Y,Gao Y,He Z,Zhou W,Chang R,Peng Z,Zheng Y,Duan C,Zhang C
SH2B1 promotes epithelial-mesenchymal transition through the IRS1/β-catenin signaling axis in lung adenocarcinoma.
MOL CARCINOGEN . 2018 May;57(5):640-652. (IF 3.825)
150. Feng S,Liu J,Cheng B,Deng A,Zhang H
(-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway.
Exp Ther Med . 2018 May;15(5):4284-4290. (IF 1.785)
151. Gao Y,Han K,Wang Q,Hu Z,Liu Q,Liu L,Zeng K
Development of podophyllotoxin‑loaded nanostructured lipid carriers for the treatment of condyloma acuminatum.
Mol Med Rep . 2018 May;17(5):6506-6514. (IF 2.1)
152. Chu P,He L,Xiong L,Luo L,Huang R,Liao L,Li Y,Zhu Z,Wang Y
Molecular cloning, expression analysis and localization pattern of the MST family in grass carp (Ctenopharyngodon idella).
FISH SHELLFISH IMMUN . 2018 May;76:316-323. (IF 3.298)
153. Han B,Zhang YY,Xu K,Bai Y,Wan LH,Miao SK,Zhang KX,Zhang HW,Liu Y,Zhou LM
NUDCD1 promotes metastasis through inducing EMT and inhibiting apoptosis in colorectal cancer.
Am J Cancer Res. 2018 May 1;8(5):810-823. eCollection 2018. (IF 5.177)
154. Gu LL,Shen ZL,Li YL,Bao YQ,Lu H
Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells.
Mol Cells . 2018 May 31;41(5):401-412. (IF 4.081)
155. Yang B,Bai Y,Yin C,Qian H,Xing G,Wang S,Li F,Bian J,Aschner M,Lu R
Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes.
Arch Toxicol . 2018 Jun;92(6):2093-2108. (IF 5.059)
156. Zhang H,Feng QQ,Gong JH,Ma JP
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Mol Med Rep . 2018 Jul;18(1):407-414. (IF 2.1)
157. Liu Y,Jiang P,Wang G,Liu X,Luo S
Downregulation of RFX1 predicts poor prognosis of patients with small hepatocellular carcinoma.
EJSO-EUR J SURG ONC . 2018 Jul;44(7):1087-1093. (IF 3.959)
158. Yu J,Chen Z,Li Y,Du M,Yan F,Zheng H
Echogenic Chitosan Nanodroplets for Spatiotemporally Controlled Gene Delivery.
J BIOMED NANOTECHNOL . 2018 Jul 1;14(7):1287-1297. (IF 5.068)
159. Zhang GL,Song JL,Zhou Y,Zhang RQ,Cheng SF,Sun XF,Qin GQ,Shen W,Li L
Differentiation of sow and mouse ovarian granulosa cells exposed to zearalenone in vitro using RNA-seq gene expression.
TOXICOL APPL PHARM . 2018 Jul 1;350:78-90. (IF 3.616)
160. Kang X,Yang MY,Shi YX,Xie MM,Zhu M,Zheng XL,Zhang CK,Ge ZL,Bian XT,Lv JT,Wang YJ,Zhou BH,Tang KL
Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors.
Cell Commun Signal . 2018 Jul 20;16(1):42. (IF 4.344)
161. Zhang GL,Song JL,Ji CL,Feng YL,Yu J,Nyachoti CM,Yang GS
Zearalenone Exposure Enhanced the Expression of Tumorigenesis Genes in Donkey Granulosa Cells via the PTEN/PI3K/AKT Signaling Pathway.
Front Genet . 2018 Jul 31;9:293. (IF 3.258)
162. Chen Z,Ma Y,Pan Y,Zhu H,Yu C,Sun C
MiR-1297 suppresses pancreatic cancer cell proliferation and metastasis by targeting MTDH.
MOL CELL PROBE . 2018 Aug;40:19-26. (IF 1.951)
163. Chen H,Cao J,Zhu Z,Zhang G,Shan L,Yu P,Wang Y,Sun Y,Zhang Z
A Novel Tetramethylpyrazine Derivative Protects Against Glutamate-Induced Cytotoxicity Through PGC1α/Nrf2 and PI3K/Akt Signaling Pathways.
FRONT NEUROSCI-SWITZ . 2018 Aug 15;12:567. (IF 3.707)
164. Zhai QY,Ge W,Wang JJ,Sun XF,Ma JM,Liu JC,Zhao Y,Feng YZ,Dyce PW,De Felici M,Shen W
Exposure to Zinc oxide nanoparticles during pregnancy induces oocyte DNA damage and affects ovarian reserve of mouse offspring.
AGING-US . 2018 Aug 28;10(8):2170-2189. (IF 4.831)
165. Zhang Z,Wei Y,Liu B,Wu Y,Wang H,Xie X,Feng Z,Shao G,Xiong Q
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Mol Immunol . 2018 Sep;101:130-139. (IF 3.641)
166. Teng F,Xu Z,Chen J,Zheng G,Zheng G,Lv H,Wang Y,Wang L,Cheng X
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167. Sun L,Hu L,Zhang P,Li H,Sun J,Wang H,Xie X,Hu J
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168. Zhao Z,Zhang Y,Tian C,Yin T,Zhang C
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BIOMATER SCI-UK . 2018 Sep 25;6(10):2605-2618. (IF 6.183)
169. Liu CX,Tan YR,Xiang Y,Liu C,Liu XA,Qin XQ
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170. Wei YL,Hua J,Liu XY,Hua XM,Sun C,Bai JA,Tang QY
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Cancer Sci . 2018 Oct;109(10):3139-3148. (IF 4.966)
171. Fang SY,Hu CQ,Liu MN,Tao L,Wang Y,Gong MJ,He Y,He TC,Bi Y
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Int J Mol Med . 2018 Oct;42(4):1977-1986. (IF 3.098)
172. Chu P,He L,Li Y,Huang R,Liao L,Li Y,Zhu Z,Wang Y
Molecular cloning and functional characterisation of NLRX1 in grass carp (Ctenopharyngodon idella).
FISH SHELLFISH IMMUN . 2018 Oct;81:276-283. (IF 3.298)
173. Liu X,Li P,Hirayama R,Niu Y,Liu X,Chen W,Jin X,Zhang P,Ye F,Zhao T,Liu B,Li Q
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways.
Radiother Oncol . 2018 Oct;129(1):84-94. (IF 4.856)
174. Shen J,Zhou T,Li H,Li W,Wang S,Song Y,Ke K,Cao M
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175. Zhang RQ,Sun XF,Wu RY,Cheng SF,Zhang GL,Zhai QY,Liu XL,Zhao Y,Shen W,Li L
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176. Zhao X,Qi T,Kong C,Hao M,Wang Y,Li J,Liu B,Gao Y,Jiang J
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177. Ma YS,Lv ZW,Yu F,Chang ZY,Cong XL,Zhong XM,Lu GX,Zhu J,Fu D
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178. Huang H,Li H,Shi K,Wang L,Zhang X,Zhu X
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179. Zhu HZ,Hou J,Guo Y,Liu X,Jiang FL,Chen GP,Pang XF,Sun JG,Chen ZT
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180. Zhong L,Jin J,Zheng D,Guan W,Guo Y,Chen A,Peng Y,Gao Q,Zheng Y,Huang H
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184. Shi R,Xiang W,Kang X,Zhang L,Wang J,Miao H,He F
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186. Jiang Y,Zhang T,Vallesi A,Yang X,Gao F
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187. Tian J,Rui K,Hong Y,Wang X,Xiao F,Lin X,Ma J,Guo H,Xu H,Ma K,Xu D,Liu D,Zhao Y,Lu L,Wang S
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188. Su W,Tang J,Wang Y,Sun S,Shen Y,Yang H
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189. Liu G,Wang Y,Zheng W,Cheng H,Zhou R
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190. Liu H,Chen J,Li X,Deng Z,Gao P,Li J,Ren T,Huang L,Yang Y,Zhong S
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191. Zeng Z,Liu Y,Zheng W,Liu L,Yin H,Zhang S,Bai H,Hua L,Wang S,Wang Z,Li X,Xiao J,Yuan Q,Wang Y
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Cell Cycle. 2019 Nov;18(22):3095-3110. (IF 3.699)
192. Li X,Liu H,Li J,Deng Z,Li L,Liu J,Yuan J,Gao P,Yang Y,Zhong S
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203. Long Fan,Leng Li,Xuhua Yu,Ziyao Liang,Tiantian Cai,Yuanbin Chen,Yinji Xu,Tao Hu,Lei Wu,Lin Lin
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206. Mengxue Sun,Jie Hua,Gaoshuang Liu,Peiyun Huang,Ningsheng Liu,Xiaopu He
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215. Fidelis Chibhabha,Yaqi Yang,Kuang Ying,Fujie Jia,Qin Zhang,Shahid Ullah,Zibin Liang,Muke Xie,Feng Li
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216. Shihai Liu,Jing Qiu,Guifang He,Chao Geng,Weitai He,Changchang Liu,Duo Cai,Huazheng Pan,Qingwu Tian
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218. Hai-Zhen Zhu,Chun-Ju Fang,Yi Guo,Qi Zhang,Li-Min Huang,Dong Qiu,Guang-Peng Chen,Xiu-Feng Pang,Jian-Jun Hu,Jian-Guo Sun,Zheng-Tang Chen
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221. Jiajia Hao,Yafen Song,Bin Tian,Changxi Qi,Liping Li,Lumei Wang,Yuxiao Xing,Xiaona Zhao,Jianzhu Liu
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ECOTOX ENVIRON SAFE. 2020 Oct 1;202:110901.;doi: 10.1016/j.ecoenv.2020.110901. (IF 4.872)
222. Xiaodan Qu,Peipei Guan,Li Han,Zhanyou Wang,Xueshi Huang
Levistolide A Attenuates Alzheimer’s Pathology Through Activation of the PPARγ Pathway
Neurotherapeutics. 2020 Oct 9.;doi: 10.1007/s13311-020-00943-1. (IF 6.035)
223. Dejun Xu,Huanshan He,Dingbang Liu,Guoxia Geng,Qingwang Li
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224. Yang Liu,Peng Qin,Rong Wu,Lianfang Du,Fan Li
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225. Yangbiao He,Xujun Lang,Dong Cheng,Ting Zhang,Zhihao Yang,Rongbing Xiong
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Gene. 2020 Nov 30;761:144971.;doi: 10.1016/j.gene.2020.144971. (IF 2.984)
227. Yiqun Ji,Jialu Yao,Yang He
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228. Yi Shen,Xiaoyi Zhang,Chenguang Li,Xiang Wang,Yong Ye,Jie Yuan,Hui Gong,Yunzeng Zou,Junbo Ge
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Ann Transl Med. 2020 Nov;8(22):1514.;doi: 10.21037/atm-20-7041. (IF 3.297)
229. Nan Wang,Yanping Feng,Jinye Xie,Hui Han,Qian Dong,Weijia Wang
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Cancer Manag Res. 2020 Dec 23;12:13285-13300.;doi: 10.2147/CMAR.S269258. (IF 2.886)
230. Ya Li,Qiuju Han,Huajun Zhao,Quanjuan Guo,Jian Zhang
Napabucasin Reduces Cancer Stem Cell Characteristics in Hepatocellular Carcinoma
Front Pharmacol. 2020 Dec 3;11:597520.;doi: 10.3389/fphar.2020.597520. (IF 4.225)
231. Yu Gu,Songtao Lai,Yang Dong,Hao Fu,Liwei Song,Tianxiang Chen,Yourong Duan,Zhen Zhang
AZD9291 Resistance Reversal Activity of a pH-Sensitive Nanocarrier Dual-Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC
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BBA-MOL CELL RES. 2020 Dec;1867(12):118826.;doi: 10.1016/j.bbamcr.2020.118826. (IF 4.105)
233. Xiangwa Chen,Tao Deng,Tingting Huo,Faqin Dong,Jianjun Deng
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234. Guanting Li,Xianwei Wu,Peng Sun,Zhiyang Zhang,Enxian Shao,Jianping Mao,Hua Cao,Hongliang Huang
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235. Yanjiao Hou,Hengmin Jia,Yanhong Cao,Shuang Zhang,Xiaolei Zhang,Pingping Wei,Jun Xie,Wenqian Dong,Baolong Wang
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236. Jing Luo,Weian Zhao,Yi Gan,Bo Pan,Lingjuan Liu,Zhenguo Liu,Jie Tian
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237. Jin Hou,Ling Zhao,Huaqiao Tang,Xiaoli He,Gang Ye,Fei Shi,Min Kang,Helin Chen,Yinglun Li
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239. Lin Chen,Jinying Xu,Shuang Lv,Yan Zhao,Dongjie Sun,Yangyang Zheng,Xianglan Li,Lihong Zhang,Guangfan Chi,Yulin Li
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The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection
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